ID A0A3B4V901_SERDU Unreviewed; 515 AA.
AC A0A3B4V901;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Centrosomal protein 57kDa-like protein 1 {ECO:0000256|ARBA:ARBA00041218};
DE AltName: Full=Cep57-related protein {ECO:0000256|ARBA:ARBA00042578};
OS Seriola dumerili (Greater amberjack) (Caranx dumerili).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Carangiformes; Carangidae; Seriola.
OX NCBI_TaxID=41447 {ECO:0000313|Ensembl:ENSSDUP00000027119.1, ECO:0000313|Proteomes:UP000261420};
RN [1] {ECO:0000313|Ensembl:ENSSDUP00000027119.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC center, centrosome {ECO:0000256|ARBA:ARBA00004300}.
CC -!- SIMILARITY: Belongs to the translokin family.
CC {ECO:0000256|ARBA:ARBA00008179}.
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DR AlphaFoldDB; A0A3B4V901; -.
DR STRING; 41447.ENSSDUP00000027119; -.
DR Ensembl; ENSSDUT00000027599.1; ENSSDUP00000027119.1; ENSSDUG00000019647.1.
DR GeneTree; ENSGT00530000063695; -.
DR OMA; TRMEDKG; -.
DR Proteomes; UP000261420; Unplaced.
DR GO; GO:0005813; C:centrosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0043015; F:gamma-tubulin binding; IEA:InterPro.
DR GO; GO:0042802; F:identical protein binding; IEA:InterPro.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR Gene3D; 1.20.58.90; -; 1.
DR InterPro; IPR025913; Cep57_CLD.
DR InterPro; IPR024957; Cep57_MT-bd_dom.
DR PANTHER; PTHR19336:SF10; CENTROSOMAL PROTEIN CEP57L1; 1.
DR PANTHER; PTHR19336; UNCHARACTERIZED DUF1167; 1.
DR Pfam; PF14073; Cep57_CLD; 1.
DR Pfam; PF06657; Cep57_MT_bd; 1.
DR SUPFAM; SSF57997; Tropomyosin; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701}.
FT DOMAIN 65..243
FT /note="Cep57 centrosome localisation"
FT /evidence="ECO:0000259|Pfam:PF14073"
FT DOMAIN 357..420
FT /note="Cep57 centrosome microtubule-binding"
FT /evidence="ECO:0000259|Pfam:PF06657"
FT REGION 92..133
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 248..277
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 326..349
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 422..450
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 209..236
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 386..413
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 96..124
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 332..349
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 515 AA; 58374 MW; 9E49409C51E9B005 CRC64;
MEMYHDQILD SPSKNSYIGS YYQPPDRIIP IPRQLEFFAP ASINTDPKIN SLRESQAKPN
IDSKAVVDAL KTLQEKIRRL ELERKQAEKS FQQFSHDIQK HQQVTASNVM PSQSAASLPE
TNNSSREELD SKLQSAEARC KVLEKQLDYM RKMVENAKKE RNALMENQAS LQNEQPSSSN
TQIQREKLDK LESDCLKLSR TQTVAEMKLA ILEQKLVKEE YERKLVQEKA DELQRELDIN
LQLSMQTAEE IKPKKKTKKT SKKTSKKNEL ASASSPRHIK MPFVAGTSIS PSHSVHANVQ
SILHMMKHHQ PQLCERVSSL HRPGCGAKKS LQKDFSPSST AFKKPDNLPE QVDRSLSSLS
DLLLALQDEL GQMSFEHQEL VRQIDAAPHR EQKQDLQREL ERLVARMEEK GVHITKLRKH
QQTVHKLTQS QPGAEEDTTK KLSGIKPPVP SLVKAKQKGR KDYRARLDTA IRLAEASQDP
SMPTYTTAPA TPVCSPDRAT LIPCDCTPLF LSSVE
//
