ID   A0A3B4V963_SERDU        Unreviewed;       348 AA.
AC   A0A3B4V963;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=tRNA wybutosine-synthesizing protein 2 homolog {ECO:0000256|ARBA:ARBA00017179};
DE            EC=2.5.1.114 {ECO:0000256|ARBA:ARBA00012265};
OS   Seriola dumerili (Greater amberjack) (Caranx dumerili).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Carangaria; Carangiformes; Carangidae; Seriola.
OX   NCBI_TaxID=41447 {ECO:0000313|Ensembl:ENSSDUP00000027331.1, ECO:0000313|Proteomes:UP000261420};
RN   [1] {ECO:0000313|Ensembl:ENSSDUP00000027331.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3B4V963; -.
DR   Ensembl; ENSSDUT00000027815.1; ENSSDUP00000027331.1; ENSSDUG00000019588.1.
DR   GeneTree; ENSGT01000000221234; -.
DR   Proteomes; UP000261420; Unplaced.
DR   GO; GO:0102522; F:tRNA 4-demethylwyosine alpha-amino-alpha-carboxypropyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006400; P:tRNA modification; IEA:UniProt.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR030382; MeTrfase_TRM5/TYW2.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR23245:SF36; TRNA (GUANINE(37)-N1)-METHYLTRANSFERASE; 1.
DR   PANTHER; PTHR23245; TRNA METHYLTRANSFERASE; 1.
DR   Pfam; PF02475; Met_10; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          107..229
FT                   /note="SAM-dependent methyltransferase TRM5/TYW2-type"
FT                   /evidence="ECO:0000259|Pfam:PF02475"
SQ   SEQUENCE   348 AA;  39119 MW;  6C6950373FB09A59 CRC64;
     RGLPHRPLQS KLYAVPLAVL KQSDEKPEKV ELSQRPRVPR VVQAYRGEAV TFVSSEALRS
     LPVSLRSCQY YELQLTYNNL KSEEVRGPVL PPGQDTDIFT ATNLSVASTV GQVIIGQNPP
     RITCVVNKTN IIDSTYRNFK MEVLAGEENM VTKVKHPEFR EDSNVDFSCV LEPPLSTEHQ
     RVWSSSNVVD TVLDVCCGVG PFAIRCWPAR VPMCWPNDSE PRSYRWLHKV RTFKPGRQRV
     VIPGTCEQEL PALMKEKANV HVGDGTCLPG FRVPGCIQRL LHRSLPVMRT YPQCTCYSFF
     KDKTMDADVV KESVAASSGS PWRQMLCAFC AFTLPKEVLS AAMMKTDR
//