ID A0A3B4VG38_SERDU Unreviewed; 3450 AA.
AC A0A3B4VG38;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=CUB and sushi domain-containing protein 1-like {ECO:0000313|Ensembl:ENSSDUP00000029537.1};
GN Name=CSMD1 {ECO:0000313|Ensembl:ENSSDUP00000029537.1};
OS Seriola dumerili (Greater amberjack) (Caranx dumerili).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Carangiformes; Carangidae; Seriola.
OX NCBI_TaxID=41447 {ECO:0000313|Ensembl:ENSSDUP00000029537.1, ECO:0000313|Proteomes:UP000261420};
RN [1] {ECO:0000313|Ensembl:ENSSDUP00000029537.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00302}.
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DR Ensembl; ENSSDUT00000030036.1; ENSSDUP00000029537.1; ENSSDUG00000021170.1.
DR GeneTree; ENSGT00940000155701; -.
DR Proteomes; UP000261420; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00033; CCP; 28.
DR CDD; cd00041; CUB; 13.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 28.
DR Gene3D; 2.60.120.290; Spermadhesin, CUB domain; 13.
DR InterPro; IPR000859; CUB_dom.
DR InterPro; IPR035914; Sperma_CUB_dom_sf.
DR InterPro; IPR035976; Sushi/SCR/CCP_sf.
DR InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR PANTHER; PTHR45656:SF3; CUB AND SUSHI DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR45656; PROTEIN CBR-CLEC-78; 1.
DR Pfam; PF00431; CUB; 13.
DR Pfam; PF00084; Sushi; 28.
DR SMART; SM00032; CCP; 28.
DR SMART; SM00042; CUB; 13.
DR SUPFAM; SSF57535; Complement control module/SCR domain; 28.
DR SUPFAM; SSF49854; Spermadhesin, CUB domain; 14.
DR PROSITE; PS01180; CUB; 13.
DR PROSITE; PS50923; SUSHI; 28.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00302}; Membrane {ECO:0000256|SAM:Phobius};
KW Sushi {ECO:0000256|PROSITE-ProRule:PRU00302};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 3374..3395
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 44..105
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 109..213
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 246..307
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 310..421
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 424..481
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 483..591
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 594..655
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 657..717
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 745..802
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 804..914
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 917..976
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 978..1086
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 1089..1149
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1151..1263
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 1266..1326
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1328..1436
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 1439..1500
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1502..1610
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 1616..1677
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1679..1787
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 1790..1849
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1851..1959
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 1962..2021
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2023..2134
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 2133..2194
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2196..2307
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 2307..2369
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2370..2431
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2432..2497
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2498..2555
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2556..2613
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2614..2671
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2672..2734
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2735..2793
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2797..2855
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2856..2914
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2915..2976
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 2977..3034
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 3035..3092
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 3096..3154
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 3155..3214
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DISULFID 452..479
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 773..800
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 1151..1178
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00059"
FT DISULFID 2526..2553
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 2584..2611
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 2642..2669
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 2705..2732
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 2764..2791
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 2826..2853
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 2885..2912
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 3005..3032
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 3063..3090
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 3125..3152
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
SQ SEQUENCE 3450 AA; 376512 MW; 4EF8993641837C75 CRC64;
MRLSGFMLPS PIVSSGSILA LWFTTDFAVS AQGFKAVYEV LPSHTCGTPG LIPNGVIHGS
RYNMGDKIRY SCESGFVLEG HSILTCIVSP GSGAQWDFPS PFCRAEGACG GTLRGTAGSI
TSPGYPAEYD NNLDCTWSIL AEPGDTIALV FNDFLLEDKY DFLEISGTEA PSIWLTGTTL
PSPVISNKNW LRIHFTSDSN HRRKGFSAQY QVKKAIELKS RGVKMMPSKD SSHKNAVLSQ
SGLAGDVCPD PGVPENGKRM GSAFQVGSSV QFSCDDSYVL QGSKSITCQR VTDTLAAWSD
HRPICRTRTC GSNLRGPRGV ITSPNYPVQY ENNAHCVWVI TAMDSGKVIK LSFEEFDLER
GYDTLTVGDG GKIGDTRRVL YVLTGSSVPD LIVSLSNQMW LHLQSDDTIG SAGFKAVYEE
IERGGCGDPG VPAFGRRSGD RFQHGDVLTF FCQSAFELVG ERTITCQHNN QWSGNKPSCV
FSCFFNFTAP SGTVLSPNYP EEYGNNLNCV WLIISEPGSR IHLLFSDFDL EPQFDWLVVK
DEGLSEPTTF GTFSGKDVPS QIASNGHIMR LEFQSDHSNT GKGFNISYTT FGQNECHDPG
VPVNGQRYGD QFQLGSSVAF RCDQGFIRTQ GSDQVTCIIQ DGNVVWSAAV PRCEAPCGGH
LTAPTGVLLS PGWPSFYKDS LNCQWVIEAQ TDHAVKIHFD RFQTEVNYDT LEIRDGPSTS
SPLIDNSRSA AGFSIRYESV KMESDSCLDP GIPVNGRRHG SSFSIGSRVS FTCDPGYTLS
DQEPIVCEQN HQWSHALPSC DALCGGYVYG KTGTILSPGF PDFYPNSLNC TWTIEVSHGK
GVHLVFHTFH LEENHDYLSI TEDGNFQVPV ARLTGSVLPP SVKAGLYGNF SAQLRFISDF
SMSYEGFNIT FSEYDLEPCE DPGVPAFSRR MGFRFRVGDS LAFSCFHGYR LEGDSKITCL
GGGRRVWSNT LPRCIAECGA SSLGPEGVLL SPNFPSNYDN NHECIYRITT EKGKGIRLKA
ESFLLQDGDY LKVYDGENTS SRLLGNFTHD AMVGHVINST SNHLWLEFNS NASGTNQGFR
LTYTSFDLVR CEEPGVPSYG YKIQDDGHYA NTFVLYSCNP GYSLHGSSTL TCLSGDRRVW
DKPLPSCIAE CGGHITGAVS GRILSPGYPA PYDNNLHCTW TIEADTGKTI SLHFIVFDTE
IGHDILRVWD GPSGPSDGGI LLKEWSGPAL PEDIHSTFNI LTLQFDSDYF ISKQGFSIQF
STTTATTCND PGIPVNGSRY GDSKEPGDSM TFQCDPGYQL EGQDTITCVR MDNRFYWQPD
PPTCVATCGG NISGPSGVIL SPNYPQPYPP GKECDWRIRV NPDFVIALIF KSFNMEPSYD
FLHIYEGEDS NGPLLASLQG NQAPERIESS GNSLFLAFRS DASLGMSGFA IEYREKPREA
CFDPGNIMNG SRTGYDYKLG SQVSYNCHHG YTTVGGDTIT CVMGHDGKPV WDRALPSCKA
PCGGQYGGSE GVVLSPNYPL NYTTRQTCSY YITVSPQFVV FGQFAVFQTA MNDSVELFDG
ANENARLLSS LAGSHSGETL PLATSNQIML RFNAKSGQSA KGFHFVYQAV PRTSDSQCSS
VPEPRYGRRI GSEFSAGSVV RFECSPGYLL KGSSAIRCQA VPGALAQWNA TTPTCIVPCS
GNVTERRGTI LSPGYPEPYP NSLNCLWRIH VSEGAGIQIQ VMTFATEHNW DSLEIYDGGD
MTAPKLGSFS GTTAPALLNS TSNQLLLHFQ SDISVVAAGF HLEYKTVGLT TCPEPMIPAN
GIKTGDRYMV NEVVAFTCEP GYTLQGHSHI SCMPGTVRRW NYPPPLCIAR CGGVLSEMSG
VILSPGFPGN YPGNLDCTWQ ITLPTGYGAH IQFQNFSSED NHDFLEVRAG AQHSSALIGQ
FTGSQIPPPL LSTTHLTIIH FYSDHSENRP GFKLTYQAYQ LQNCQDPFPF SNGDIINSDY
SAGQSVTFQC YPGYVLIGHP VLTCLHGTNR KWNHPFPRCE APCGYNVTAE NGTIYSPQYP
NEYPNSQDCI WLITVPHGHG VYINFTLLQT EPVTDYIAVW DGPDTSSPQL GVFSGNTALE
SAYSTSPKVL IRFHSDFSTG GFFILNFHAY RLKKCPPPPV VENAEVIFED EDFQIGDIVK
YRCLPGYTLT GKAELMCKLN SHLLFEDPPP TCQAQCPANE ERSASSGVIL SPGFPSNYPN
SQTCSWLLRM VPGYTINIYV EMFHSEKQFD ELEIFDGSSG QSPLLVALSG NHSSQLNFTS
KTNQLYLRWS TDHATNKRGF KIRYSAAYCS INDPPVNGGV VNRTKLRPGS RLQFFCNRGY
RLVGTTNATC KLHSNGLFQW DTLPPFCQAI SCGIPQSPGN GSFHAYQYTV GSQVTYQCNH
GYHLDPDVSV TAVCLEDGSW SNAASAPRCL PVHCPSIDSI LSDHMTYHLL YGRLGEFGSM
MMLECSSGYY LGVGHRTLRC LANGTWEGSD DPATCKIISC GELPSPPFGT KLGTLTTFGA
TAIFMCNHGY TLVGSHVREC GANGLWSGAE TRCLAGHCDS PDRIVNGHIS GDGSSYRDTV
VYQCMLGYRL IGTSVRICQQ DHRWSGTTPV CVPITCGHPG NPANGRTNGS EFNLNDVVNF
TCNRGYILSG NARAQCRLNG QWSSPLPVCK VVNCSDPGHV ENGVRQSGLR YPEVFSYGVS
VAIHCKRGFY LLGSALLTCQ HDGRWDRPIP RCQAISCGDP GVPPNAVVSG THSWTYSSVL
QYSCLPGGVL IGNATRHCQE DGTWSGAPPY CTGVSPGVCG DPGIPPHGAR LGGQEFKTKS
LLRFSCEAGY SLTGSAERTC LHNGTWSGTQ PVCQAVSCGN PGTPAHGRIV FSDGITFGNS
VAYACWEGFK TSGLTTRHCT TNGTWTGQPP DCTVISCGDP GPVANGIYLG NEFTFNHTVT
YRCNPGHLME PPGPGRSVLR CTKDGTWNQT KPNCKVIQCG PPPQVHHGKV EGTDHSWGSS
VSYSCFHGYQ LSTPAVLTCE GNGTWTGDVP QCLPVLCGDP GSPGGGFREG NIFSYRSEVR
FYCHAPYLLV GSASRVCEAD GIWSGQQPAC IDPAFNNCRD PGTPAYGIPV IAQGFQVGSK
ISFKCRKNYH ILGSTTRTCL ENLTWSGTQP ECIAHSCRQP ETPSNVDIRS MDLPTLGYTL
IYTCQDGFYL AGGSEHRTCK SDGRWSGKPP LCKVGVKVNP KGRGESDVQK NKIRVPVDVF
SPNSEWSGFY EYLGKRQPTT FTVTGFNATS GRVNVTLLET SGVSIRLSGT YKSEENQLLL
KVYQVKGPTE HYYSKFKNDN WAMDGYVTAE SDQKTFVYQG HIHSKDFGKF HLTRQGPVTI
AMDPSNPYTN SSSVAAAILV PFFALILSGF AFYLYKHRTR PKVQFNGYVG HESSNGQASF
ENPMYDTNMK PTEAKAVRFD TTLNTVCTVV
//
