ID A0A3B4VIF5_SERDU Unreviewed; 1732 AA.
AC A0A3B4VIF5;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Rapamycin-insensitive companion of mTOR-like {ECO:0000313|Ensembl:ENSSDUP00000030736.1};
GN Name=RICTOR {ECO:0000313|Ensembl:ENSSDUP00000030736.1};
OS Seriola dumerili (Greater amberjack) (Caranx dumerili).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Carangiformes; Carangidae; Seriola.
OX NCBI_TaxID=41447 {ECO:0000313|Ensembl:ENSSDUP00000030736.1, ECO:0000313|Proteomes:UP000261420};
RN [1] {ECO:0000313|Ensembl:ENSSDUP00000030736.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the RICTOR family.
CC {ECO:0000256|ARBA:ARBA00008878}.
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DR STRING; 41447.ENSSDUP00000030736; -.
DR Ensembl; ENSSDUT00000031271.1; ENSSDUP00000030736.1; ENSSDUG00000022102.1.
DR GeneTree; ENSGT00390000002096; -.
DR Proteomes; UP000261420; Unplaced.
DR GO; GO:0031932; C:TORC2 complex; IEA:InterPro.
DR GO; GO:0031929; P:TOR signaling; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR028268; Pianissimo_fam.
DR InterPro; IPR028267; Pianissimo_N.
DR InterPro; IPR029453; Rictor_IV.
DR InterPro; IPR029451; RICTOR_M.
DR InterPro; IPR029259; RICTOR_phospho.
DR InterPro; IPR029452; RICTOR_V.
DR PANTHER; PTHR13298; CYTOSOLIC REGULATOR PIANISSIMO; 1.
DR PANTHER; PTHR13298:SF11; RAPAMYCIN-INSENSITIVE COMPANION OF MTOR; 1.
DR Pfam; PF14663; RasGEF_N_2; 1.
DR Pfam; PF14666; RICTOR_M; 1.
DR Pfam; PF14664; RICTOR_N; 1.
DR Pfam; PF14665; RICTOR_phospho; 1.
DR Pfam; PF14668; RICTOR_V; 1.
DR SMART; SM01303; RasGEF_N_2; 1.
DR SMART; SM01307; RICTOR_M; 1.
DR SMART; SM01308; RICTOR_N; 1.
DR SMART; SM01309; RICTOR_phospho; 2.
DR SMART; SM01310; RICTOR_V; 1.
DR SUPFAM; SSF48371; ARM repeat; 2.
PE 3: Inferred from homology;
FT DOMAIN 57..439
FT /note="Rapamycin-insensitive companion of mTOR N-terminal"
FT /evidence="ECO:0000259|SMART:SM01308"
FT DOMAIN 523..742
FT /note="Rapamycin-insensitive companion of mTOR middle"
FT /evidence="ECO:0000259|SMART:SM01307"
FT DOMAIN 920..992
FT /note="Rapamycin-insensitive companion of mTOR"
FT /evidence="ECO:0000259|SMART:SM01310"
FT REGION 1019..1043
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1096..1126
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1151..1284
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1300..1337
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1152..1166
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1199..1213
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1215..1229
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1237..1268
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1732 AA; 192524 MW; F0F432B33A7BDD3F CRC64;
MAASFRGRPI RSLRMRGRND SGEENVPLDL TREPSENFRE ILQNVAKPHG VSNMRKLGHL
NNFIKLLCSI GHREENFGFT HEEIIVCLRL ALLNEAKEVR AAGLRALRYL IRDTSVLQKV
LRLQVDYLIA RCIDIQQSNE GERTQALRLV RKIITVNAML FPTSIANSLI AVGTDGLQER
DRMVRAAIAI VCELALKNPE VVAKRGGLST ILKSVIDCQL SRINEALITT ILHLLNHPRT
RQYVRIDVEL EQILAPFTDF HYRHNADTAE GQLKEDREAR FLSSRMAIVA AFRSWSGIIN
LCKAGNPGIQ SLIGLLCIPN MEVRKGLLEV LYEIFRLPVP IVTQDFTEAL LSVDPARFQD
TWRLSDGFVA AEAKVILPHR ARSRPDLMDN YLGFVLSAFI TSGLLEGLVE VVTSSDDQLA
IRATILLGEL LHMANTILPH SHSHHLHCLP TLINMAASFD ISQEKRLRAS AAVNNLKRFH
EKKKKGLKPH SLYLDHIIRK SVSSHNRRES HSRVHRDIYV IKDTEEALMM NLRDSHILNH
KQNLEWNWLL IATILKWPNV NLRNNKDEQM HKFVRRLLYF YKPSSKLYAG LALDHVKARQ
LTVVGCQFVE FLMDSDEDGQ GYLEDLVKDM VSWLSSSSGL KPERCLQSNG LLTTLSQHYF
LFLGTLSAHP QGVKLLEKCG LFQCLLNLCS VKNQDAVLKL AVSTLDYSRD GLARVILSKI
LTAATDTCRL YATKHLRVLL RAGVEFFSSW GMELLVTQLH DHSKAVSMEA LDILDEACED
KANLHALIQL KPALSHLGDK GLLLLLRFLS IPKGFSYLNE RGYVSKQLDK WQKEYNLKYV
DLIEEQLNEA LTTYRKPVDG DNYVRRSNQR LQRPNVYLPV HLYGQLVHDK TGCHLLEAQS
VVPDLSYTVR SPMLDTWEGI KQLKAALWAL GNIGSSNWGL NLLQEENVIP DILTLAQHCE
VLSVRGTCVY VLGVISKTRQ GCEVLKQYGW DAVRHSRRTL WPVTPDEVDT QLTSELSSVP
STLSLNSEST SSRHNSESES QPNMYILDDD KCDALDQSDE PSFYLHPKPV KDRSPFTILA
STRFVRTRLL NSLSLPSKKL RSTSDPKTPS GSRTPTELKT GSMRRNRTVT EPSVYSPNQG
DVFAPVFNGR GMQKSPTVSL ETSFVGNRGG SEEHLVDGRL ARGGGSGLGL SGLGGHGAVE
HPSREREQSS RERLAGGDGG SSSSGGNVGS GGGGGGGTQF KSRSQSFNTD TTTSGISSMS
SSPSRETVGN PEHPEPEPDS SDCVSLNTVV SAKTVKTLSS LTPQAQTNHM SMSKSSTVSL
VPPGSSHTLP RRAQSLKSPS VTTIKSLADC SFMYTSPRDA LGYATLKRLQ QQRIHPSLSH
SEALASPAKD VLFTDTITMK TGSLDSRLTP RRFLKALSFA SLDKEELLSP INQSTLHRCS
SVRSMVSSAT FGCNDDYIGL ALPMDINDMF HIRDSAYFQQ RISPPSEERK RFLFGDGDGD
RPAIPVLKQQ FSISELIVCR GDSQNHTVGS EETGLQDHTE ENCLYCVGSM VLGYPTQPQI
NSTHPRTDYV DFPSWGGQSG HRLEVMPQSK FSGVSGCSDA AVSQGSICST PTPGDIVIGG
KAISEDGPAS RVLLRKEVLR LIINLSSSVG TKGHETGLLT IKEKFSYAFD DICLYSEVSH
LLAHCMFRLT SRRFIQELFQ DVQFMPMYEE AEAILTKLPK PVEEDVDPPT ES
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