ID A0A3B4VMC3_SERDU Unreviewed; 343 AA.
AC A0A3B4VMC3;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Syntaxin-18 {ECO:0000256|ARBA:ARBA00019409};
OS Seriola dumerili (Greater amberjack) (Caranx dumerili).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Carangiformes; Carangidae; Seriola.
OX NCBI_TaxID=41447 {ECO:0000313|Ensembl:ENSSDUP00000031747.1, ECO:0000313|Proteomes:UP000261420};
RN [1] {ECO:0000313|Ensembl:ENSSDUP00000031747.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- FUNCTION: Syntaxin that may be involved in targeting and fusion of
CC Golgi-derived retrograde transport vesicles with the ER.
CC {ECO:0000256|ARBA:ARBA00003746}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004163}; Single-pass type IV membrane protein
CC {ECO:0000256|ARBA:ARBA00004163}. Membrane
CC {ECO:0000256|ARBA:ARBA00004211}; Single-pass type IV membrane protein
CC {ECO:0000256|ARBA:ARBA00004211}.
CC -!- SIMILARITY: Belongs to the syntaxin family.
CC {ECO:0000256|ARBA:ARBA00009063}.
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DR AlphaFoldDB; A0A3B4VMC3; -.
DR STRING; 41447.ENSSDUP00000031747; -.
DR Ensembl; ENSSDUT00000032298.1; ENSSDUP00000031747.1; ENSSDUG00000022822.1.
DR GeneTree; ENSGT00390000014853; -.
DR OMA; PVNLWEE; -.
DR Proteomes; UP000261420; Unplaced.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005484; F:SNAP receptor activity; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
DR CDD; cd15850; SNARE_syntaxin18; 1.
DR Gene3D; 1.20.5.110; -; 1.
DR InterPro; IPR010989; SNARE.
DR InterPro; IPR019529; Syntaxin-18_N.
DR InterPro; IPR006012; Syntaxin/epimorphin_CS.
DR PANTHER; PTHR15959; SYNTAXIN-18; 1.
DR PANTHER; PTHR15959:SF0; SYNTAXIN-18; 1.
DR Pfam; PF10496; Syntaxin-18_N; 1.
DR SUPFAM; SSF58038; SNARE fusion complex; 1.
DR SUPFAM; SSF47661; t-snare proteins; 1.
DR PROSITE; PS00914; SYNTAXIN; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW ER-Golgi transport {ECO:0000256|ARBA:ARBA00022892};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 320..341
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 23..110
FT /note="SNARE-complex protein Syntaxin-18 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF10496"
FT REGION 180..214
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 240..267
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 343 AA; 39443 MW; BA03D6A22806F3DA CRC64;
MTLSLGDVSV CLQRCSCTNM AVDITLLFKA SVKTVKTRNK AIGIGFDSTK DEIFKRSRPK
SGFSPKAKEV ITNITKLKDF LLQHRKDYVS AGSLISSDLT RMTDSERDQI DQDAQIFMRT
CSEAIKQLRN EAEKKVTSAQ IKEHRGAVLD LIEMYLKGVC KLYSEQRAIR VKRMVDKKRM
SRLAPEHHSH VEKTREVEPT EEKTVKEESS EKSVSEVLDN TVEHLWEEGR VEDELSPEEI
QMFEQENQRL VSEMNSLVDE VRQIEGKVVE ISRLQEIFAE KVLQQETEID SIHQLVVGAT
ENVKEGNEDI REAIKNNAGF RVWILFFLVM CSFSLLFLDW YDS
//
