ID   A0A3B4VQT1_SERDU        Unreviewed;       190 AA.
AC   A0A3B4VQT1;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=Somatotropin {ECO:0000256|ARBA:ARBA00018367};
DE   AltName: Full=Growth hormone {ECO:0000256|ARBA:ARBA00032367};
OS   Seriola dumerili (Greater amberjack) (Caranx dumerili).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Carangaria; Carangiformes; Carangidae; Seriola.
OX   NCBI_TaxID=41447 {ECO:0000313|Ensembl:ENSSDUP00000033002.1, ECO:0000313|Proteomes:UP000261420};
RN   [1] {ECO:0000313|Ensembl:ENSSDUP00000033002.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613,
CC       ECO:0000256|RuleBase:RU003618}.
CC   -!- SIMILARITY: Belongs to the somatotropin/prolactin family.
CC       {ECO:0000256|ARBA:ARBA00008474, ECO:0000256|RuleBase:RU003618}.
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DR   AlphaFoldDB; A0A3B4VQT1; -.
DR   Ensembl; ENSSDUT00000033565.1; ENSSDUP00000033002.1; ENSSDUG00000023703.1.
DR   GeneTree; ENSGT00950000182818; -.
DR   Proteomes; UP000261420; Unplaced.
DR   GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR   GO; GO:0005131; F:growth hormone receptor binding; IEA:InterPro.
DR   GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
DR   CDD; cd10285; somatotropin_like; 1.
DR   Gene3D; 1.20.1250.10; -; 1.
DR   InterPro; IPR009079; 4_helix_cytokine-like_core.
DR   InterPro; IPR034975; Somatotropin.
DR   InterPro; IPR001400; Somatotropin/Prolactin.
DR   InterPro; IPR018116; Somatotropin_CS.
DR   PANTHER; PTHR11417:SF2; SOMATOTROPIN; 1.
DR   PANTHER; PTHR11417; SOMATOTROPIN,PROLACTIN; 1.
DR   Pfam; PF00103; Hormone_1; 1.
DR   PRINTS; PR00836; SOMATOTROPIN.
DR   SUPFAM; SSF47266; 4-helical cytokines; 1.
DR   PROSITE; PS00266; SOMATOTROPIN_1; 1.
DR   PROSITE; PS00338; SOMATOTROPIN_2; 1.
PE   3: Inferred from homology;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Hormone {ECO:0000256|ARBA:ARBA00022702, ECO:0000256|RuleBase:RU003618};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           18..190
FT                   /note="Somatotropin"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5017190811"
SQ   SEQUENCE   190 AA;  21484 MW;  14B30FF91ACBE36B CRC64;
     SLSVVLLLSV LSLGVSSQPI TDSQHLFSIA VSRIQNLHLL AQRLFSNFES TLQTEDQRQL
     NKIFLQDFCN SDYIISPIDK HETQRSSVLK LLSISYRLVE SWEFSSRFLS GGSALRNQIS
     PRLSELKTGI QLLITANQDG AEMFSDVSAL QLLLRRNYEL LACFKKDMHK VETYLTVAKC
     RLSPEANCTL
//