ID A0A3B4VS50_SERDU Unreviewed; 835 AA.
AC A0A3B4VS50;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Extracellular calcium-sensing receptor-like {ECO:0000313|Ensembl:ENSSDUP00000032980.1};
OS Seriola dumerili (Greater amberjack) (Caranx dumerili).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Carangiformes; Carangidae; Seriola.
OX NCBI_TaxID=41447 {ECO:0000313|Ensembl:ENSSDUP00000032980.1, ECO:0000313|Proteomes:UP000261420};
RN [1] {ECO:0000313|Ensembl:ENSSDUP00000032980.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR AlphaFoldDB; A0A3B4VS50; -.
DR Ensembl; ENSSDUT00000033543.1; ENSSDUP00000032980.1; ENSSDUG00000023690.1.
DR GeneTree; ENSGT00940000162782; -.
DR OMA; RTITIVW; -.
DR Proteomes; UP000261420; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR CDD; cd15283; 7tmC_V2R_pheromone; 1.
DR CDD; cd06364; PBP1_CaSR; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 2.10.50.30; GPCR, family 3, nine cysteines domain; 1.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR000337; GPCR_3.
DR InterPro; IPR011500; GPCR_3_9-Cys_dom.
DR InterPro; IPR038550; GPCR_3_9-Cys_sf.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR000068; GPCR_3_Ca_sens_rcpt-rel.
DR InterPro; IPR017979; GPCR_3_CS.
DR InterPro; IPR004073; GPCR_3_vmron_rcpt_2.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR24061:SF418; C-FAMILY ODORANT RECEPTOR OLFCQ19-RELATED; 1.
DR PANTHER; PTHR24061; CALCIUM-SENSING RECEPTOR-RELATED; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF07562; NCD3G; 1.
DR PRINTS; PR00248; GPCRMGR.
DR PRINTS; PR01535; VOMERONASL2R.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00981; G_PROTEIN_RECEP_F3_3; 1.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 566..591
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 603..625
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 637..661
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 682..700
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 727..750
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 762..782
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 794..817
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 567..832
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
SQ SEQUENCE 835 AA; 92821 MW; B1E0D2B1CF05BA49 CRC64;
MHKAGDVVLG GLFQIHFFST YPGLSYTSEP QQPTCHGFDV LGFRQAQTMA FAIDEINRNS
HLLPNVTLGY SLYDNCLQLG IGFRAALTLT SGLEEKVTLH ETCVGTPPVL GIVGDSSSTR
SIAISTVLGL YRVPMVSYFA TCSCLSDRQK FPSFFRTIPS DAFQVRAMIQ ILKYFGWTWA
GLLISDDDYG LHAARSFQTD LGPSGGGCLA YTEILPWGDN PAEFRRIVDL MKISTAHVVI
VFAHESHMID LMKEVVRQNV TGLQWIASEA WTSAAVLQTP HLMPYLGGTL GIAIRRGEIP
GLREFMSQIY PDLHHNNSYG NNVVNQFWEY TFKCRFAPAA AGWVEAGGAL CTGHEDVENV
ESEFLDISNL RSEYNVYKAV YALAYALDDM MQCEPGRGPF SRSSCAYLQR LEPWQLVYYL
EKVNFTTPFG DQVSFDENGD VLPIYDIMNW QWLPDGRITV QNVGEVKKSA LKGEELTLDE
DKIFWNFESK EPPRSVCSES CPPGTRMARK KGEPECCFDC IPCSEGKISN KTDSMECTSC
QEDFWSSPQR DHCVLKKTEF LSYHEPLGIC LATISLLGAF MCALVLCIFI YHRQTPIVRA
NNSELSFQLL LSLKLCFLCS LLFIGRPKLW TCQLRHAAFG ISFVLCVSCI LVKTMVVLAV
FKASKPGGEA SLKWFGAVQQ RGTVLVLTSV QAAICTAWLV SSSPAPHKNT QYHNDKIVYE
CVVGSTIGFA VLLGYIGLLA ILSFLLAFLA RNLPDSFNEA KLITFSMLIF CALWVAFVPA
YISSPGKYSD AVEVFAILAS SFGLLLALFG PKCYIILLRP EKNTKKAIMG RRTES
//
