ID   A0A3B4WAX8_SERLL        Unreviewed;      1163 AA.
AC   A0A3B4WAX8;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Cartilage intermediate layer protein {ECO:0000313|Ensembl:ENSSLDP00000000785.1};
OS   Seriola lalandi dorsalis.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Carangaria; Carangiformes; Carangidae; Seriola.
OX   NCBI_TaxID=1841481 {ECO:0000313|Ensembl:ENSSLDP00000000785.1, ECO:0000313|Proteomes:UP000261360};
RN   [1] {ECO:0000313|Ensembl:ENSSLDP00000000785.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC       matrix {ECO:0000256|ARBA:ARBA00004498}.
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DR   AlphaFoldDB; A0A3B4WAX8; -.
DR   STRING; 1841481.ENSSLDP00000000785; -.
DR   Ensembl; ENSSLDT00000000844.1; ENSSLDP00000000785.1; ENSSLDG00000000691.1.
DR   GeneTree; ENSGT00390000008152; -.
DR   OrthoDB; 5383253at2759; -.
DR   Proteomes; UP000261360; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   Gene3D; 2.20.100.10; Thrombospondin type-1 (TSP1) repeat; 1.
DR   InterPro; IPR008969; CarboxyPept-like_regulatory.
DR   InterPro; IPR039675; CILP1/CILP2.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR003598; Ig_sub2.
DR   InterPro; IPR000884; TSP1_rpt.
DR   InterPro; IPR036383; TSP1_rpt_sf.
DR   InterPro; IPR025155; WxxW_domain.
DR   PANTHER; PTHR15031:SF5; CARTILAGE INTERMEDIATE LAYER PROTEIN 1 ISOFORM X1; 1.
DR   PANTHER; PTHR15031; CARTILAGE INTERMEDIATE LAYER PROTEIN CLIP; 1.
DR   Pfam; PF13927; Ig_3; 1.
DR   Pfam; PF13330; Mucin2_WxxW; 1.
DR   Pfam; PF00090; TSP_1; 1.
DR   SMART; SM00409; IG; 1.
DR   SMART; SM00408; IGc2; 1.
DR   SMART; SM00209; TSP1; 1.
DR   SUPFAM; SSF49464; Carboxypeptidase regulatory domain-like; 1.
DR   SUPFAM; SSF48726; Immunoglobulin; 1.
DR   SUPFAM; SSF82895; TSP-1 type 1 repeat; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
DR   PROSITE; PS50092; TSP1; 1.
PE   4: Predicted;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|ARBA:ARBA00022989};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022989};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           21..1163
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5017356401"
FT   DOMAIN          275..375
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   REGION          1113..1163
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1113..1129
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1138..1152
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1163 AA;  129501 MW;  7A463DF9BE0C3AF6 CRC64;
     MSLRSLLLIL GITAASVVTA QGSWRKDNKE SGPAVYHSDE NFEWTTWFNV DHPGGRGDYE
     QLEAIRFYYR ARVCETPRAI EARTTEWVPA RETGEKVHAD PTVGFWCLNV EQGPERNCSN
     YAVRFLCPKD NSVKTQGTWG PWSGWSPCPA LCGQLGVQVR SRNCQSHSVP CSGPKVEGKA
     CNGHECPKAD CSLQCVMGRA NAECDTCMCE EHILLGSVRG AGGLIAVGAT ILRYGKLLTL
     TDHNGHFRIP GICPDGNTTL TVSLQGHATL NVVVPNSAEH TSVLSVQLKR TEKLHVLSNP
     ESKARRQGQT AAFCCKVAGT PQPDKYQWFH NNSLMEKQSE NTLVLKGLRP EQAGEYYCRA
     SGASGAIKTK PATLKVLGRN EHSCNPKPES HLIRLPHDCY QNSTNSFYYD VGKCPSSTCT
     GQLDNGIRCK DKVVYCCGVE KMEERQLTCQ GYQLPTMVVT ECGCQKCVDT KAIVHGRAIA
     ADNGEPMRFG HIFMNGVRIS RTGYKGTFSI QVPPDTERLV LTFVDNMQKF VNTTKVLPFN
     TKGGAVYHEI KLLRKKAPVT ISSTETSTLE LGEVEGQEAM VQLQIPPHSF YKENGEVYMG
     NVNASVTFLD PRDVSTAAAA QSDLNFVGDE GDTLPLRTYG MFSVDFRGEE NNEPLNAGEV
     KVLLDSAQVT MPEHLNTMKL WSLNPDTGLW EEEGSLQVEK KRRGKREERT FLIGNMEIRE
     RRLFNLDVPE NRRCYVKVRA FRSERFMPSE QVEGVVVSLI NMEPTAGYSS NPRAWGRFDS
     VITGSNGACL PAFCDEQKAD AYSAYVMANL AGEELEAVPS APKLNPNLVG VPQPYLGKLN
     YKRTDHEDPR VKKTAFSINV AKPSPNTAEE GNGPVYAFEK LKECEEAPFS AAHFRFSRVE
     GDRYDYNTVP FNEDDPMSWT EDYLSWWPKP MEYRACYIKV KINSPHEINV RSRNMGGTHP
     KTVGQLYGLR DSRSIRDMDQ TTVSAVCLEF KCSGMLYDQE RVDRTLVKVI PQGSCKRDHV
     NTMLQEYLVN HLPLAVNNDT NEFTMLAPLD PLGHNYGIYT VTDQDPRTAK EIALGRCFDG
     TSDGTSRVMK SNEGVALTFT CGDREVSRQS VFQAQQSSQG QTVTSVVRGE GRQNRRRQRA
     NAPRSSRRRS TRNPTGRRTD ATS
//