ID A0A3B4WG53_SERLL Unreviewed; 795 AA.
AC A0A3B4WG53;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Protocadherin 2 alpha a 15 {ECO:0000313|Ensembl:ENSSLDP00000001487.1};
OS Seriola lalandi dorsalis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Carangiformes; Carangidae; Seriola.
OX NCBI_TaxID=1841481 {ECO:0000313|Ensembl:ENSSLDP00000001487.1, ECO:0000313|Proteomes:UP000261360};
RN [1] {ECO:0000313|Ensembl:ENSSLDP00000001487.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3B4WG53; -.
DR Ensembl; ENSSLDT00000001569.1; ENSSLDP00000001487.1; ENSSLDG00000001252.1.
DR GeneTree; ENSGT00940000165118; -.
DR Proteomes; UP000261360; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR CDD; cd11304; Cadherin_repeat; 6.
DR Gene3D; 2.60.40.60; Cadherins; 6.
DR InterPro; IPR002126; Cadherin-like_dom.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR032455; Cadherin_C.
DR InterPro; IPR020894; Cadherin_CS.
DR InterPro; IPR013164; Cadherin_N.
DR PANTHER; PTHR24028; CADHERIN-87A; 1.
DR PANTHER; PTHR24028:SF290; PROTOCADHERIN1-ALPHA-AV15-VCP-RELATED; 1.
DR Pfam; PF00028; Cadherin; 5.
DR Pfam; PF08266; Cadherin_2; 1.
DR Pfam; PF16492; Cadherin_C_2; 1.
DR PRINTS; PR00205; CADHERIN.
DR SMART; SM00112; CA; 6.
DR SUPFAM; SSF49313; Cadherin-like; 6.
DR PROSITE; PS00232; CADHERIN_1; 3.
DR PROSITE; PS50268; CADHERIN_2; 6.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW ProRule:PRU00043}; Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Membrane {ECO:0000256|SAM:Phobius}; Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 695..718
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 29..135
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 136..244
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 245..352
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 353..458
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 459..567
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 582..681
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
SQ SEQUENCE 795 AA; 88637 MW; 2A83DA3E0A9645AA CRC64;
MEKSGRQAWN ERWTCIAYMV LLVTFWNEAS AQIRYSISEE VKEGSIVGHI AKDLGIDKAT
LKDREYRIVG SSTEPLFHLN KDDGILYVNR KVDREEICER SNACVINLKT VLENPLEIHY
VAIEVLDIND HSPIFPEKEK RLEIFESTLP GARFQLQPAR DPDGGQFSVQ QYKLSQNDHF
RLEVKERGED RKMPFLILQK QLDREAKREH KLLLSAIDGG RPAKSGTIEI LIEVLDVNDN
SPVFTQDVYS ATLNENAAPG TLIIQVNATD LDESTNSEIV YSFGKEVDVN VQKLFNIDSE
TGEIIVIGVI DFEEKKSYDI DIQASDKGPV PLSTDRTVVI KVIDLNDNSP EIEVTSFSKS
VPEDSRTGTT VALISVNDLD SGLNGKVSCF IRENVPFAIS PSLQDNMYAI VTKSPLDREE
NSFYELSIVA KDTGEPPLSS EKTISVVVSD VNDNRPQFSL SPYTFYVTEN NDLTAPVFSV
RASDLDESDN AHISYHIPRD SSGDSIGLFL NINSESGGIM ALKSFDFETL KTFRFHVVAS
DSGTPSLSSN VTVNVFILDQ NDNAPVILYP LSSNGSAEGV EEIPRNVNAG HLVTKVRAYD
ADIGYNGWLL FSLQEVTDHS LFGLDRYTGQ IRTLRSFTET DDAEHKLVIL VKDNGNVSLS
ATATVIVKLV EPKEAFAASD VKSSAKADEE NNVTFYLMIT LGSVSALFLI SIIVLIAMQC
SKSTDYTSKY LQETNYDGTL CHSIQYRSGD KRYMLVGPRM RDTFTRTQTL PNNDKVRTYE
KATQDFILRV VAVNV
//
