ID A0A3B4WIB0_SERLL Unreviewed; 761 AA.
AC A0A3B4WIB0;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Neural EGFL like 1 {ECO:0000313|Ensembl:ENSSLDP00000003670.1};
GN Name=NELL1 {ECO:0000313|Ensembl:ENSSLDP00000003670.1};
OS Seriola lalandi dorsalis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Carangiformes; Carangidae; Seriola.
OX NCBI_TaxID=1841481 {ECO:0000313|Ensembl:ENSSLDP00000003670.1, ECO:0000313|Proteomes:UP000261360};
RN [1] {ECO:0000313|Ensembl:ENSSLDP00000003670.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR AlphaFoldDB; A0A3B4WIB0; -.
DR Ensembl; ENSSLDT00000003797.1; ENSSLDP00000003670.1; ENSSLDG00000002809.1.
DR GeneTree; ENSGT00810000125439; -.
DR Proteomes; UP000261360; Unplaced.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0048513; P:animal organ development; IEA:UniProt.
DR CDD; cd00054; EGF_CA; 3.
DR CDD; cd00110; LamG; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 6.20.200.20; -; 2.
DR Gene3D; 2.10.25.10; Laminin; 5.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR024731; EGF_dom.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR001791; Laminin_G.
DR InterPro; IPR048287; TSPN-like_N.
DR InterPro; IPR001007; VWF_dom.
DR PANTHER; PTHR24042; NEL HOMOLOG; 1.
DR PANTHER; PTHR24042:SF2; PROTEIN KINASE C-BINDING PROTEIN NELL1; 1.
DR Pfam; PF12947; EGF_3; 1.
DR Pfam; PF07645; EGF_CA; 2.
DR Pfam; PF02210; Laminin_G_2; 1.
DR Pfam; PF00093; VWC; 2.
DR SMART; SM00181; EGF; 5.
DR SMART; SM00179; EGF_CA; 4.
DR SMART; SM00282; LamG; 1.
DR SMART; SM00210; TSPN; 1.
DR SMART; SM00214; VWC; 3.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 1.
DR SUPFAM; SSF57603; FnI-like domain; 3.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR PROSITE; PS00010; ASX_HYDROXYL; 1.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS01186; EGF_2; 3.
DR PROSITE; PS50026; EGF_3; 4.
DR PROSITE; PS01187; EGF_CA; 1.
DR PROSITE; PS01208; VWFC_1; 2.
DR PROSITE; PS50184; VWFC_2; 2.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..761
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017286186"
FT DOMAIN 269..330
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
FT DOMAIN 432..473
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 474..514
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 515..545
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 547..582
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 643..701
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
FT DISULFID 517..527
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 535..544
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 761 AA; 84592 MW; 70C0FAF1BEB9DFA2 CRC64;
MDIYVALLSF FFFTKPALAF GSDQDYQIDI INELDLANAT YGITQVAGLH NSSKAFLFRD
VGRAVHAPAH ITEKVVQLFR SKSEFTFLAS IQQKSSTSGV IFSIHESEHS YFELESSGVR
EEIRYHYRFK GKPRSESFPY RLADGQWHKI ALTISASHLL LHVDCNRIYE RVIDPPQMEL
TPGSGVWLGQ HSHKHGLFKG IIQDVKLIFA PNGYITQCPN LNRTCPTCSD FLSLVQGIMD
LQELLAKMTL KLNYAESRLT QLEGCHCERT CSANGLVYRD KELWMEPENC RNCACKNGVV
ECRRIFCPPA NCSEDSLPVH VDGTCCKKCR PRCTYMGQTF SEGQHFLSRS CRECKNGLMV
KVTETCPEIN CTISEQILPD GRCCNVCRGY DFCAEGLICG ENSECKNRNT KAECECKSGY
ASIHGDSTYC EDIDECATQM HYCQSNTVCV NLPGSHRCDC LPGFIRVDEY SCTEHDECAS
GQNLCDENAI CTNTIRGHLC TCKPGYVGNG TICRAFCEEG CRSGGTCVSP NTCVCPSGFT
GRRCETDIDE CSLQTHTCWN DSVCVNLPGG YDCVCTSGPG CSGDCPQEEG IRRNGEDWKP
SFDRCAICSC KDGQTYCRRR PCDCGDPDED LFCCPGCDNR PSSQCLDQNG RTLYRSGASW
LYGCQQCRCM EGEVDCWPLV CPVLMCEYTA VAEGECCPRC VTDPCMADNL SYDIRQTCED
PAGVARLSGD TWHMPNSPCT TCKCKNGNVC CSVDLDCLQN N
//
