ID A0A3B4WJS0_SERLL Unreviewed; 974 AA.
AC A0A3B4WJS0;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Sorting nexin 14 {ECO:0000313|Ensembl:ENSSLDP00000004854.1};
GN Name=SNX14 {ECO:0000313|Ensembl:ENSSLDP00000004854.1};
OS Seriola lalandi dorsalis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Carangiformes; Carangidae; Seriola.
OX NCBI_TaxID=1841481 {ECO:0000313|Ensembl:ENSSLDP00000004854.1, ECO:0000313|Proteomes:UP000261360};
RN [1] {ECO:0000313|Ensembl:ENSSLDP00000004854.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the sorting nexin family.
CC {ECO:0000256|ARBA:ARBA00010883}.
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DR AlphaFoldDB; A0A3B4WJS0; -.
DR Ensembl; ENSSLDT00000005012.1; ENSSLDP00000004854.1; ENSSLDG00000003610.1.
DR GeneTree; ENSGT00950000182856; -.
DR Proteomes; UP000261360; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IEA:InterPro.
DR CDD; cd06877; PX_SNX14; 1.
DR CDD; cd08722; RGS_SNX14; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR Gene3D; 1.10.167.10; Regulator of G-protein Signalling 4, domain 2; 1.
DR InterPro; IPR003114; Phox_assoc.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR016137; RGS.
DR InterPro; IPR036305; RGS_sf.
DR InterPro; IPR044926; RGS_subdomain_2.
DR InterPro; IPR037436; SNX14_PX.
DR InterPro; IPR037892; SNX14_RGS.
DR InterPro; IPR013937; Sorting_nexin_C.
DR PANTHER; PTHR22775; SORTING NEXIN; 1.
DR PANTHER; PTHR22775:SF44; SORTING NEXIN-14; 1.
DR Pfam; PF08628; Nexin_C; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF02194; PXA; 1.
DR Pfam; PF00615; RGS; 1.
DR SMART; SM00312; PX; 1.
DR SMART; SM00313; PXA; 1.
DR SMART; SM00315; RGS; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR SUPFAM; SSF48097; Regulator of G-protein signaling, RGS; 1.
DR PROSITE; PS50195; PX; 1.
DR PROSITE; PS51207; PXA; 1.
DR PROSITE; PS50132; RGS; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 27..44
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 128..296
FT /note="PXA"
FT /evidence="ECO:0000259|PROSITE:PS51207"
FT DOMAIN 319..451
FT /note="RGS"
FT /evidence="ECO:0000259|PROSITE:PS50132"
FT DOMAIN 597..717
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
SQ SEQUENCE 974 AA; 112911 MW; CDDC080CA7E15ABE CRC64;
MGCIRAYLQK IRRRIKLDRL RELGRQYPVF CFLLLVLLLS TVLLNRYIQI IMVFWSFLAG
VVTFYCSLGP ESLLPNILLS IKPKTKSYQQ ELFPLGHSCA VCGKIKCKRH RPTLLLENYQ
PWLDLKVPSK VDASLSEILE LVLENFVYPW YRDVTDDEAF VDELRVTLRF FAAVLVRRTQ
KVDVASLITQ KLLKVSMKHI EIISKARQKV KNTEYLQQAA LEEYGPDLHV ALRGRRDELL
YLRKLTEMLF PYILPPKATD CRSLTLLIRE VLAGSVFLPS MDYLADPPEE ATEPTSTLVP
FLQKYSDTRN KKPSVLKLEL KEIREQQDLL FRFMNFLKQE GAVHVLQFCL AVEEFNDRIL
CPELSDSEKM MLHEEVKKIY ETYCLDESVD KILFDPFIVE EIRNIAEGPH AEVVKLQTMR
CLFEAYEHVL SLLENVFTPM FCHSDEYFRQ LLRGAESPAR NSKMSRNSLS LDDIRSWDWS
PESPSSLFTA SGSSSPASFN SLHAQSTFTT FPYGSLSHRH SSPKNTSKRG ESFGISRIGS
KIKGVFKSTT MEGAMLPSYG LVEGEDDMVE EAMMVLEDDS PMEVASTPST PRNLSAWNIT
IPYIDFYDDD VKRERIPVFC IDVERNDRKA VGHETEHWSV YRRYLEFYVL ESKLTEFHGS
FPDAQLPSKR IIGPKNYEFL TSKREDFQEY LQKLLQHPEL SNSQLLADFL SPHSMESQFL
DKMLPDVNLG KIIKSVPSKL IKEKGQHLEP FIQSFFNSCE SPKPKPSRPE LTILSPTSEN
DKKLFNDLFK NNANRSEMAE KRHNQNYFME MITVEGVYDY LMYVGRVIFH IPDWLHHLLM
GGRILFKNTL EAYTDYYLQY KLNQVVQEHR LVSLITLLRD TVFCESSPPR STQDKQRRAK
KTFEEMMSYI PDFLGKCIGE EAKYEGVRLL FDGLQQPVLN KQLTYVLLDI AIQELFPELN
KQVQKETSVM APWM
//
