ID A0A3B4WMB6_SERLL Unreviewed; 410 AA.
AC A0A3B4WMB6;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Sex comb on midleg-like protein 4 {ECO:0000313|Ensembl:ENSSLDP00000002548.1};
GN Name=SCML4 {ECO:0000313|Ensembl:ENSSLDP00000002548.1};
OS Seriola lalandi dorsalis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Carangiformes; Carangidae; Seriola.
OX NCBI_TaxID=1841481 {ECO:0000313|Ensembl:ENSSLDP00000002548.1, ECO:0000313|Proteomes:UP000261360};
RN [1] {ECO:0000313|Ensembl:ENSSLDP00000002548.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the SCM family. {ECO:0000256|ARBA:ARBA00008469}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A3B4WMB6; -.
DR STRING; 1841481.ENSSLDP00000002548; -.
DR Ensembl; ENSSLDT00000002656.1; ENSSLDP00000002548.1; ENSSLDG00000002066.1.
DR GeneTree; ENSGT00940000157463; -.
DR OrthoDB; 2908161at2759; -.
DR Proteomes; UP000261360; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR CDD; cd09578; SAM_Scm; 1.
DR Gene3D; 3.90.1150.190; SLED domain; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR047531; SAM_Scm-like.
DR InterPro; IPR033763; SCML2_RBR.
DR InterPro; IPR021987; SLED.
DR InterPro; IPR038348; SLED_sf.
DR PANTHER; PTHR12247; POLYCOMB GROUP PROTEIN; 1.
DR PANTHER; PTHR12247:SF85; SEX COMB ON MIDLEG-LIKE PROTEIN 4; 1.
DR Pfam; PF17208; RBR; 1.
DR Pfam; PF00536; SAM_1; 1.
DR Pfam; PF12140; SLED; 1.
DR SMART; SM00454; SAM; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Repressor {ECO:0000256|ARBA:ARBA00022491}.
FT DOMAIN 339..408
FT /note="SAM"
FT /evidence="ECO:0000259|SMART:SM00454"
FT REGION 1..79
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 233..267
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 298..340
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..30
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 233..247
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 249..263
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 298..338
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 410 AA; 45012 MW; 21C610F29F8DAA7D CRC64;
MLQMSVPAAT AQKSDGNNSE MQSAAVAPSF IPSQTGKIPG RKRGRPPLRN VAKMDFPNRY
PESLPPLKVP KKRGRKPGFK LKPRMVMTPL AISPPSSTPE PDMSSIPQDA ATIPHSATPQ
VLTVCIYINK QANTGPNLDR KKIQQLPDHF GPDRPSVVLQ QAVQGCIDSA FQQKTVFTLL
TQGYGGEKIS ATFDGKQHLL SLPVVNSIDY VLRFLKKLCR SLHCENLFSD QPITQHSGGS
YQSDAETSMA EDYHLDQSDG KRYSVDPGDS AFSSISSSYS PKSSYGFRSS QQFSNGSASM
SMCRQSSTSP NTFPESNRTG GYNASPESQE SKAPPNKDPS TWSVEDVVWF IRDADPQALG
PHADVFRKHE IDGNALLLLK SDMIMKYLGL KLGPALKLCY HIDKLKQTKF
//
