ID   A0A3B4WP97_SERLL        Unreviewed;       260 AA.
AC   A0A3B4WP97;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   RecName: Full=Proliferating cell nuclear antigen {ECO:0000256|ARBA:ARBA00020229, ECO:0000256|RuleBase:RU000641};
OS   Seriola lalandi dorsalis.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Carangaria; Carangiformes; Carangidae; Seriola.
OX   NCBI_TaxID=1841481 {ECO:0000313|Ensembl:ENSSLDP00000006599.1, ECO:0000313|Proteomes:UP000261360};
RN   [1] {ECO:0000313|Ensembl:ENSSLDP00000006599.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- FUNCTION: This protein is an auxiliary protein of DNA polymerase delta
CC       and is involved in the control of eukaryotic DNA replication by
CC       increasing the polymerase's processibility during elongation of the
CC       leading strand. {ECO:0000256|RuleBase:RU000641}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU000641}.
CC   -!- SIMILARITY: Belongs to the PCNA family. {ECO:0000256|ARBA:ARBA00010462,
CC       ECO:0000256|RuleBase:RU003671}.
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DR   AlphaFoldDB; A0A3B4WP97; -.
DR   SMR; A0A3B4WP97; -.
DR   STRING; 1841481.ENSSLDP00000006599; -.
DR   Ensembl; ENSSLDT00000006819.1; ENSSLDP00000006599.1; ENSSLDG00000005279.1.
DR   GeneTree; ENSGT00390000004965; -.
DR   OrthoDB; 118939at2759; -.
DR   Proteomes; UP000261360; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030337; F:DNA polymerase processivity factor activity; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   GO; GO:0014823; P:response to activity; IEA:Ensembl.
DR   GO; GO:0009617; P:response to bacterium; IEA:Ensembl.
DR   CDD; cd00577; PCNA; 1.
DR   Gene3D; 3.10.150.10; DNA Polymerase III, subunit A, domain 2; 2.
DR   HAMAP; MF_00317; DNApol_clamp_arch; 1.
DR   InterPro; IPR046938; DNA_clamp_sf.
DR   InterPro; IPR000730; Pr_cel_nuc_antig.
DR   InterPro; IPR022649; Pr_cel_nuc_antig_C.
DR   InterPro; IPR022659; Pr_cel_nuc_antig_CS.
DR   InterPro; IPR022648; Pr_cel_nuc_antig_N.
DR   NCBIfam; TIGR00590; pcna; 1.
DR   PANTHER; PTHR11352; PROLIFERATING CELL NUCLEAR ANTIGEN; 1.
DR   PANTHER; PTHR11352:SF0; PROLIFERATING CELL NUCLEAR ANTIGEN; 1.
DR   Pfam; PF02747; PCNA_C; 1.
DR   Pfam; PF00705; PCNA_N; 1.
DR   PRINTS; PR00339; PCNACYCLIN.
DR   SUPFAM; SSF55979; DNA clamp; 2.
DR   PROSITE; PS01251; PCNA_1; 1.
DR   PROSITE; PS00293; PCNA_2; 1.
PE   3: Inferred from homology;
KW   DNA replication {ECO:0000256|RuleBase:RU003671};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU003671};
KW   Nucleus {ECO:0000256|RuleBase:RU000641}.
FT   DOMAIN          1..124
FT                   /note="Proliferating cell nuclear antigen PCNA N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00705"
FT   DOMAIN          127..254
FT                   /note="Proliferating cell nuclear antigen PCNA C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02747"
SQ   SEQUENCE   260 AA;  28689 MW;  A9701765B59532E6 CRC64;
     MFEARLVQGS ILKKVLEALK DLITEACWDV SSSGISLQSM DSSHVSLVQL TLRHDGFDSY
     RCDRNLAMGV NLSSMSKILK CAGNEDIITL RAEDNADTLA LVFETLNQEK VSDYEMKLMD
     LDVEQLGIPE QEYSCVVKMP SGEFARICRD LSQIGDAVMI SCAKDGVKFS ASGELGTGNI
     KLSQTSNVDK EDEAVTIEMN EPVQLIFALN YLNFFTKATP LSKTVTLSMS ADIPLVVEYK
     IADMGHIKYY LAPKIDEEAS
//