ID A0A3B4WTZ1_SERLL Unreviewed; 334 AA.
AC A0A3B4WTZ1;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=SAM pointed domain-containing Ets transcription factor-like {ECO:0000313|Ensembl:ENSSLDP00000006357.1};
GN Name=SPDEF {ECO:0000313|Ensembl:ENSSLDP00000006357.1};
OS Seriola lalandi dorsalis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Carangiformes; Carangidae; Seriola.
OX NCBI_TaxID=1841481 {ECO:0000313|Ensembl:ENSSLDP00000006357.1, ECO:0000313|Proteomes:UP000261360};
RN [1] {ECO:0000313|Ensembl:ENSSLDP00000006357.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU004019}.
CC -!- SIMILARITY: Belongs to the ETS family. {ECO:0000256|ARBA:ARBA00005562,
CC ECO:0000256|RuleBase:RU004019}.
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DR AlphaFoldDB; A0A3B4WTZ1; -.
DR STRING; 1841481.ENSSLDP00000006357; -.
DR Ensembl; ENSSLDT00000006573.1; ENSSLDP00000006357.1; ENSSLDG00000005067.1.
DR GeneTree; ENSGT00940000157549; -.
DR OrthoDB; 3980839at2759; -.
DR Proteomes; UP000261360; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd08532; SAM_PNT-PDEF-like; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000418; Ets_dom.
DR InterPro; IPR046328; ETS_fam.
DR InterPro; IPR003118; Pointed_dom.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11849; ETS; 1.
DR PANTHER; PTHR11849:SF182; SAM POINTED DOMAIN-CONTAINING ETS TRANSCRIPTION FACTOR; 1.
DR Pfam; PF00178; Ets; 1.
DR Pfam; PF02198; SAM_PNT; 1.
DR PRINTS; PR00454; ETSDOMAIN.
DR SMART; SM00413; ETS; 1.
DR SMART; SM00251; SAM_PNT; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00346; ETS_DOMAIN_2; 1.
DR PROSITE; PS50061; ETS_DOMAIN_3; 1.
DR PROSITE; PS51433; PNT; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004019};
KW Nucleus {ECO:0000256|RuleBase:RU004019};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 132..216
FT /note="PNT"
FT /evidence="ECO:0000259|PROSITE:PS51433"
FT DOMAIN 248..331
FT /note="ETS"
FT /evidence="ECO:0000259|PROSITE:PS50061"
FT REGION 91..117
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 334 AA; 37942 MW; 61ED3803F1468DC5 CRC64;
MSNSVGSLSD GTVYGSRIGM TEDSLALLER NRGSGDPWDM GETKPNMEAL ERGMPGLYLS
CFDMLLTEDA AWLVKVSEAS PTLALPMTHM EPQEEPEQCP VIDSQEQGLS PGLEGQEEER
SLEQVQSMVV GEVLKDIETA CKLLNITPDP IEWSTGNVQK WLLWTEHLYR LPHAGKSFQE
LTGKDLCAMS EEEFRQRSPQ CGDTLHAHLD IWKSAAWMKE RCSAGDTKTT GSEELWSEAD
SSCSGQPIHL WQFLRELLLK PHSYGRCIRW LNKEKGIFKI EDSAHVARLW GLRKNRPAMN
YDKLSRSIRQ YYKKGIIRKP DVSQRLVYQF VHPV
//
