ID A0A3B4WXK4_SERLL Unreviewed; 484 AA.
AC A0A3B4WXK4;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=Meis homeobox 2 {ECO:0000313|Ensembl:ENSSLDP00000009884.1};
GN Name=MEIS2 {ECO:0000313|Ensembl:ENSSLDP00000009884.1};
OS Seriola lalandi dorsalis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Carangiformes; Carangidae; Seriola.
OX NCBI_TaxID=1841481 {ECO:0000313|Ensembl:ENSSLDP00000009884.1, ECO:0000313|Proteomes:UP000261360};
RN [1] {ECO:0000313|Ensembl:ENSSLDP00000009884.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108}.
CC -!- SIMILARITY: Belongs to the TALE/MEIS homeobox family.
CC {ECO:0000256|ARBA:ARBA00009661}.
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DR AlphaFoldDB; A0A3B4WXK4; -.
DR STRING; 1841481.ENSSLDP00000009884; -.
DR Ensembl; ENSSLDT00000010237.1; ENSSLDP00000009884.1; ENSSLDG00000007869.1.
DR GeneTree; ENSGT00940000155643; -.
DR OrthoDB; 3180467at2759; -.
DR Proteomes; UP000261360; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR008422; Homeobox_KN_domain.
DR InterPro; IPR032453; PKNOX/Meis_N.
DR PANTHER; PTHR11850:SF47; HOMEOBOX PROTEIN MEIS2; 1.
DR PANTHER; PTHR11850; HOMEOBOX PROTEIN TRANSCRIPTION FACTORS; 1.
DR Pfam; PF05920; Homeobox_KN; 1.
DR Pfam; PF16493; Meis_PKNOX_N; 1.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 3: Inferred from homology;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}.
FT DOMAIN 272..335
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 274..336
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 191..281
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 458..484
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 225..256
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 484 AA; 52763 MW; 37F9645955CD96D8 CRC64;
MAQRYDELAH YGGMDGVPAS MYGDPHAPRP LPQVHHLNHG PPLHASQHYG AHAPHPNVMP
TSMGSAVNDV LKRDKDQIYG HPLFPLLALV FEKCELATCT PREPGVAGGD VCSSDSFNED
IAVFAKQVRA EKPLFSSNPE LDNLMIQAIQ VLRFHLLELE KVHELCDNFC HRYISCLKGK
MPIDLVIDER DGSSKSDHEE LSGSSTNLAD HNPASWRDHD DATSTHSAGT PGPSSGGHAS
QSGDNSSEQG DGLDNSVASP GTGDDDDPDK DKKRQKKRGI FPKVATNIMR AWLFQHLTHP
YPSEEQKKQL AQDTGLTILQ VNNWFINARR RIVQPMIDQS NRAGFLLDPS VSQGAAYSPE
GQPMGSFVLD GQQHMGIRPA GLPGMPGEYV PQSGPMGMSM APPTYTNPHQ MTSHPSQLRH
GPPLHAYLPD HPHAHHPHHQ PHHAMLMHGG PLSHPGMTMS AQRPPLLTPI DPSTGGQGLD
IHAQ
//
