ID A0A3B4X150_SERLL Unreviewed; 612 AA.
AC A0A3B4X150;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Netrin 4 {ECO:0000313|Ensembl:ENSSLDP00000006613.1};
OS Seriola lalandi dorsalis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Carangiformes; Carangidae; Seriola.
OX NCBI_TaxID=1841481 {ECO:0000313|Ensembl:ENSSLDP00000006613.1, ECO:0000313|Proteomes:UP000261360};
RN [1] {ECO:0000313|Ensembl:ENSSLDP00000006613.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00460}.
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DR AlphaFoldDB; A0A3B4X150; -.
DR STRING; 1841481.ENSSLDP00000006613; -.
DR Ensembl; ENSSLDT00000006833.1; ENSSLDP00000006613.1; ENSSLDG00000005247.1.
DR GeneTree; ENSGT00940000156615; -.
DR Proteomes; UP000261360; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0048514; P:blood vessel morphogenesis; IEA:Ensembl.
DR CDD; cd00055; EGF_Lam; 3.
DR Gene3D; 2.40.50.120; -; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR InterPro; IPR008211; Laminin_N.
DR InterPro; IPR002049; LE_dom.
DR InterPro; IPR001134; Netrin_domain.
DR InterPro; IPR018933; Netrin_module_non-TIMP.
DR InterPro; IPR008993; TIMP-like_OB-fold.
DR PANTHER; PTHR10574:SF435; LAMININ SUBUNIT GAMMA-1; 1.
DR PANTHER; PTHR10574; NETRIN/LAMININ-RELATED; 1.
DR Pfam; PF00053; Laminin_EGF; 3.
DR Pfam; PF00055; Laminin_N; 1.
DR Pfam; PF01759; NTR; 1.
DR PRINTS; PR00011; EGFLAMININ.
DR SMART; SM00643; C345C; 1.
DR SMART; SM00180; EGF_Lam; 3.
DR SMART; SM00136; LamNT; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 3.
DR SUPFAM; SSF50242; TIMP-like; 1.
DR PROSITE; PS01248; EGF_LAM_1; 1.
DR PROSITE; PS50027; EGF_LAM_2; 3.
DR PROSITE; PS51117; LAMININ_NTER; 1.
DR PROSITE; PS50189; NTR; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00460};
KW Laminin EGF-like domain {ECO:0000256|ARBA:ARBA00023292,
KW ECO:0000256|PROSITE-ProRule:PRU00460};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..612
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017235451"
FT DOMAIN 25..259
FT /note="Laminin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51117"
FT DOMAIN 260..323
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 324..385
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 386..439
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 488..610
FT /note="NTR"
FT /evidence="ECO:0000259|PROSITE:PS50189"
FT DISULFID 287..296
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 353..362
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 413..422
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
SQ SEQUENCE 612 AA; 67845 MW; 26AA96E6F5DD7361 CRC64;
LLLLLLLILH FGSFVFRAGV APRCESRACN PRMGNLALGR RVLTQTVCGN NGTELYCSYS
DPNANLACSA AKCAKCNAGL PLLSHLAGAM SDSSFRHPNT WWQSAEGAES ETVQLDLEAE
FYFTHLIVVF RSPRPAAMTL ERSQDFGRTW KMLQYYAGNC SDTFGLEEGG SGRDGATCTS
KYSGAYPCNR GEVIFRTLPK WESLDPFGLE GQQQLRVTNI RIRLLRHQPC PCQAKDLAFA
REALPTRHFA IYDLIVKGSC FCNGHAEQCV PVLPSTYHLL VHGKCVCRHN TAGDHCERCA
PLYNDRPWQP ADGLTGAPHE CRKCKCNGHA QSCHFDWSAW RESGQRSGGV CDCLHNTEGR
QCQKCKAGFY RDPHRPQTAP DSCKPCNCHP LGSMPFHLAD GSSCDPSNGN CICKPGVGGA
HCDRCMVGYW GFHEYGCRPC DCAGDCDPFT GDCISDLDLY NLEGNSSEPV RIFRADELFS
ALHYSGKCEC KEQALTNSKL FCTMNYAYVL KVKVLSAHDK GSHAEVEVKV QKVLSQNTKV
KIQRGRVTLY PESWTARGCT CPILNPGVEY LVAGHSDRKQ GRLLVNMKSF VKPWKTNLGR
KVLTLLKTDC NW
//
