ID A0A3B4X5G3_SERLL Unreviewed; 149 AA.
AC A0A3B4X5G3;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Gonadotropin subunit beta-2 {ECO:0000313|Ensembl:ENSSLDP00000010977.1};
OS Seriola lalandi dorsalis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Carangiformes; Carangidae; Seriola.
OX NCBI_TaxID=1841481 {ECO:0000313|Ensembl:ENSSLDP00000010977.1, ECO:0000313|Proteomes:UP000261360};
RN [1] {ECO:0000313|Ensembl:ENSSLDP00000010977.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- FUNCTION: Involved in gametogenesis and steroidogenesis.
CC {ECO:0000256|ARBA:ARBA00003920}.
CC -!- SUBUNIT: Heterodimer of an alpha and a beta chain.
CC {ECO:0000256|ARBA:ARBA00011870}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613,
CC ECO:0000256|RuleBase:RU004069}.
CC -!- SIMILARITY: Belongs to the glycoprotein hormones subunit beta family.
CC {ECO:0000256|ARBA:ARBA00006552, ECO:0000256|RuleBase:RU004069}.
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DR AlphaFoldDB; A0A3B4X5G3; -.
DR STRING; 1841481.ENSSLDP00000010977; -.
DR Ensembl; ENSSLDT00000011379.1; ENSSLDP00000010977.1; ENSSLDG00000007612.1.
DR GeneTree; ENSGT00940000161285; -.
DR Proteomes; UP000261360; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
DR GO; GO:0008585; P:female gonad development; IEA:Ensembl.
DR GO; GO:0001556; P:oocyte maturation; IEA:Ensembl.
DR GO; GO:0030728; P:ovulation; IEA:Ensembl.
DR GO; GO:0007530; P:sex determination; IEA:Ensembl.
DR GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR CDD; cd00069; GHB_like; 1.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR006208; Glyco_hormone_CN.
DR InterPro; IPR001545; Gonadotropin_bsu.
DR InterPro; IPR018245; Gonadotropin_bsu_CS.
DR PANTHER; PTHR11515; GLYCOPROTEIN HORMONE BETA CHAIN; 1.
DR PANTHER; PTHR11515:SF11; LUTROPIN SUBUNIT BETA; 1.
DR Pfam; PF00007; Cys_knot; 1.
DR SMART; SM00068; GHB; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS00261; GLYCO_HORMONE_BETA_1; 1.
DR PROSITE; PS00689; GLYCO_HORMONE_BETA_2; 1.
PE 3: Inferred from homology;
KW Hormone {ECO:0000256|ARBA:ARBA00022702, ECO:0000256|RuleBase:RU004069};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..34
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 35..149
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017359679"
FT DOMAIN 38..141
FT /note="Glycoprotein hormone subunit beta"
FT /evidence="ECO:0000259|Pfam:PF00007"
SQ SEQUENCE 149 AA; 16658 MW; C1CD454B7F0160B2 CRC64;
RMTAPQVTRV ILPLMLSLFL GAPSSIWPLA PAAAFQLPPC QLINQTVSLE KEGCPKCHAV
ETTICSGHCI TKDPVIKIPF SNVYQHVCTY RDLYYRTFDL PDCPPDVNPT VTYPVALSCH
CGRCAMDTSD CTFESLQPDF CMNDILFYY
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