ID   A0A3B4X5R0_SERLL        Unreviewed;       365 AA.
AC   A0A3B4X5R0;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   SubName: Full=Ras association domain family member 1 {ECO:0000313|Ensembl:ENSSLDP00000011481.1};
GN   Name=RASSF1 {ECO:0000313|Ensembl:ENSSLDP00000011481.1};
OS   Seriola lalandi dorsalis.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Carangaria; Carangiformes; Carangidae; Seriola.
OX   NCBI_TaxID=1841481 {ECO:0000313|Ensembl:ENSSLDP00000011481.1, ECO:0000313|Proteomes:UP000261360};
RN   [1] {ECO:0000313|Ensembl:ENSSLDP00000011481.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC       {ECO:0000256|ARBA:ARBA00004245}.
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DR   AlphaFoldDB; A0A3B4X5R0; -.
DR   STRING; 1841481.ENSSLDP00000011481; -.
DR   Ensembl; ENSSLDT00000011894.1; ENSSLDP00000011481.1; ENSSLDG00000009122.1.
DR   GeneTree; ENSGT00940000155664; -.
DR   OrthoDB; 4260488at2759; -.
DR   Proteomes; UP000261360; Unplaced.
DR   GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0048468; P:cell development; IEA:UniProt.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd20885; C1_RASSF1; 1.
DR   Gene3D; 1.20.5.110; -; 1.
DR   Gene3D; 3.30.60.20; -; 1.
DR   InterPro; IPR046349; C1-like_sf.
DR   InterPro; IPR020454; DAG/PE-bd.
DR   InterPro; IPR002219; PE/DAG-bd.
DR   InterPro; IPR000159; RA_dom.
DR   InterPro; IPR033614; RASSF1-6.
DR   InterPro; IPR011524; SARAH_dom.
DR   InterPro; IPR029071; Ubiquitin-like_domsf.
DR   PANTHER; PTHR22738:SF12; RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 1; 1.
DR   PANTHER; PTHR22738; RASSF; 1.
DR   Pfam; PF00130; C1_1; 1.
DR   Pfam; PF16517; Nore1-SARAH; 1.
DR   Pfam; PF00788; RA; 1.
DR   PRINTS; PR00008; DAGPEDOMAIN.
DR   SMART; SM00109; C1; 1.
DR   SMART; SM00314; RA; 1.
DR   SUPFAM; SSF57889; Cysteine-rich domain; 1.
DR   SUPFAM; SSF54236; Ubiquitin-like; 1.
DR   PROSITE; PS50200; RA; 1.
DR   PROSITE; PS50951; SARAH; 1.
DR   PROSITE; PS00479; ZF_DAG_PE_1; 1.
DR   PROSITE; PS50081; ZF_DAG_PE_2; 1.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00023212};
KW   Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   DOMAIN          74..124
FT                   /note="Phorbol-ester/DAG-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50081"
FT   DOMAIN          223..313
FT                   /note="Ras-associating"
FT                   /evidence="ECO:0000259|PROSITE:PS50200"
FT   DOMAIN          315..362
FT                   /note="SARAH"
FT                   /evidence="ECO:0000259|PROSITE:PS50951"
SQ   SEQUENCE   365 AA;  41479 MW;  681D138B11B76F43 CRC64;
     MSCGEFIELR DLRNNREQIE LTSTHSPCSP PRLERTNALR ISPGKVPDLL SRVGIIRVLS
     STQDPQLKEE KGEGHNFQPC SHAQPTWCDL CGDFIWGLYK QSLRCVNCRF TCHYRCRALI
     QLDCSLDEGS VSDQTCVVEH TIETDTNVDE QIDCGKQELT TADIQQKVKE YNSQINSNLF
     MNMNKDGSYT GFVKVQFKLV RPVSVPHPKK GGQDAGGRKA SGVKRRTSFY LPKDASKHLH
     ISSRTSAREV IEALLKKFTV VDNPGKFALF ERSERHDQVY VRKLSDAERP LRLRLCAGPS
     EKVLSFVIKE NETGEVNWHA FSMPELKNFL RILQREEEEH VKQIVQRYAL ARTKMQEALA
     GSTPG
//