ID A0A3B4X6E2_SERLL Unreviewed; 625 AA.
AC A0A3B4X6E2;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Kinesin-like protein {ECO:0000256|RuleBase:RU000394};
OS Seriola lalandi dorsalis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Carangiformes; Carangidae; Seriola.
OX NCBI_TaxID=1841481 {ECO:0000313|Ensembl:ENSSLDP00000011696.1, ECO:0000313|Proteomes:UP000261360};
RN [1] {ECO:0000313|Ensembl:ENSSLDP00000011696.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. {ECO:0000256|PROSITE-ProRule:PRU00283,
CC ECO:0000256|RuleBase:RU000394}.
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DR AlphaFoldDB; A0A3B4X6E2; -.
DR STRING; 1841481.ENSSLDP00000011696; -.
DR Ensembl; ENSSLDT00000012119.1; ENSSLDP00000011696.1; ENSSLDG00000009314.1.
DR GeneTree; ENSGT00940000159632; -.
DR OrthoDB; 129693at2759; -.
DR Proteomes; UP000261360; Unplaced.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR CDD; cd01376; KISc_KID_like; 1.
DR Gene3D; 1.10.150.280; AF1531-like domain; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR InterPro; IPR003583; Hlx-hairpin-Hlx_DNA-bd_motif.
DR InterPro; IPR027640; Kinesin-like_fam.
DR InterPro; IPR019821; Kinesin_motor_CS.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010994; RuvA_2-like.
DR PANTHER; PTHR24115:SF1000; KINESIN-LIKE PROTEIN KIF22; 1.
DR PANTHER; PTHR24115; KINESIN-RELATED; 1.
DR Pfam; PF12836; HHH_3; 1.
DR Pfam; PF00225; Kinesin; 1.
DR PRINTS; PR00380; KINESINHEAVY.
DR SMART; SM00278; HhH1; 2.
DR SMART; SM00129; KISc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF47781; RuvA domain 2-like; 1.
DR PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00283}; Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Isopeptide bond {ECO:0000256|ARBA:ARBA00022499};
KW Microtubule {ECO:0000256|RuleBase:RU000394};
KW Motor protein {ECO:0000256|PROSITE-ProRule:PRU00283,
KW ECO:0000256|RuleBase:RU000394};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00283}; Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT DOMAIN 17..340
FT /note="Kinesin motor"
FT /evidence="ECO:0000259|PROSITE:PS50067"
FT REGION 356..398
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 521..540
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 422..449
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 357..389
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 101..108
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00283"
SQ SEQUENCE 625 AA; 70116 MW; 1CED9A4E2AEEB3EA CRC64;
MAQRVAVSDG GNKKSSRVRV AVRLRPYMDK QDGKGEGPCV RGLDSQNLEI INWRNATETV
KYHFDAFHGE QTTQQEVFLS SVKPILPHIL NGQNASVFAY GPTGAGKTHT MLGSSEQPGV
IPRAVGEVFK LVKAEDEGWD YSIGMSYLEI YNEKVLDLLS PSSQDLPIRE DKDKNIFIPG
LTHTTITSFN DFDKQFVPAS LNRTTASTKL NQRSSRSHAI LLIKVVRTQC ALPHRQQTGK
LYLVDLAGSE DNRRTGNQGI RLKESGAINL SLFTLSKVVD SLNSGTAVRV PYRDSKLTRL
LQDSLGGSAH SVMITNIAPE YKYYFDTFNA LNFAAKSKLI VNKPFTRETV AMPVLPVKRA
REDDEARGSG TQPHKKRQKE EKKTEQDGSS PSAHFHSLSE PSVMDRLIAL EKLMMSCQDK
DKTSMLKDVA QSRKEIQELK EKQREFESKA LLFSRLAEEK SSTKQEPVFK DNMAPLQRKH
TNAAKPKKQQ AVVQPLQVTQ LQPLQQLAVG KKQSVCLKKK EKKLSDQVEP PDGKENRMEN
DWESQLETSV LEQSRQKILQ VLNSGSLKEL KGLQQIGDKK AKLILGWREI HGHFTKLEDL
AKVEGMTEKR FSSFMKANIL SAMGK
//
