ID   A0A3B4X7P5_SERLL        Unreviewed;       300 AA.
AC   A0A3B4X7P5;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=Synaptophysin {ECO:0000256|ARBA:ARBA00014277};
OS   Seriola lalandi dorsalis.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Carangaria; Carangiformes; Carangidae; Seriola.
OX   NCBI_TaxID=1841481 {ECO:0000313|Ensembl:ENSSLDP00000008648.1, ECO:0000313|Proteomes:UP000261360};
RN   [1] {ECO:0000313|Ensembl:ENSSLDP00000008648.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, synaptic
CC       vesicle membrane {ECO:0000256|ARBA:ARBA00004644}; Multi-pass membrane
CC       protein {ECO:0000256|ARBA:ARBA00004644}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}. Synapse, synaptosome
CC       {ECO:0000256|ARBA:ARBA00034102}.
CC   -!- SIMILARITY: Belongs to the synaptophysin/synaptobrevin family.
CC       {ECO:0000256|ARBA:ARBA00006476}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A3B4X7P5; -.
DR   STRING; 1841481.ENSSLDP00000008648; -.
DR   Ensembl; ENSSLDT00000008935.1; ENSSLDP00000008648.1; ENSSLDG00000006865.1.
DR   GeneTree; ENSGT01030000234637; -.
DR   Proteomes; UP000261360; Unplaced.
DR   GO; GO:0043005; C:neuron projection; IEA:UniProtKB-KW.
DR   GO; GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR008253; Marvel.
DR   InterPro; IPR001285; Synaptophysin/porin.
DR   PANTHER; PTHR10306; SYNAPTOPHYSIN; 1.
DR   PANTHER; PTHR10306:SF10; SYNAPTOPHYSIN; 1.
DR   Pfam; PF01284; MARVEL; 1.
DR   PRINTS; PR00220; SYNAPTOPHYSN.
DR   PROSITE; PS51225; MARVEL; 1.
PE   3: Inferred from homology;
KW   Calcium {ECO:0000256|ARBA:ARBA00022837};
KW   Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW   Membrane {ECO:0000256|PROSITE-ProRule:PRU00581, ECO:0000256|SAM:Phobius};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Synapse {ECO:0000256|ARBA:ARBA00023018};
KW   Synaptosome {ECO:0000256|ARBA:ARBA00022599};
KW   Transmembrane {ECO:0000256|PROSITE-ProRule:PRU00581,
KW   ECO:0000256|SAM:Phobius}; Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT   TRANSMEM        108..130
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        142..163
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        207..225
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          22..229
FT                   /note="MARVEL"
FT                   /evidence="ECO:0000259|PROSITE:PS51225"
FT   REGION          253..300
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        257..300
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   300 AA;  33298 MW;  518FDE7C84E4E729 CRC64;
     MTISNCCVSL CLQLVAQGQF RVLKVPLGFI KVLEWFFAIF AFSTCGSYSG MFRMSVECKN
     RTDSDLSIEV EFEYPFRLHQ VYFDAPVCNA GETERLFLVG DYSSSAEFFV TIGVFAFLYS
     TAALSIYVFF FEKYKENNKG PLIDLGVTGV FAFMWLVSSA AWAKGLSDVK SATDPDRVIT
     LIKACKGEGN RCREVHDPVM SGLNTSVAFG FINLILWAGN LWFVFKETGI IAPFMRAPPP
     EGKPAAPEAY AQQGAYEQDP YASNQAGYQP DYSQQGYNQD AEYGQGYGQQ GAPTSFSNQM
//