ID   A0A3B4XJ57_SERLL        Unreviewed;       689 AA.
AC   A0A3B4XJ57;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Neoverrucotoxin subunit beta-like {ECO:0000313|Ensembl:ENSSLDP00000016271.1};
OS   Seriola lalandi dorsalis.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Carangaria; Carangiformes; Carangidae; Seriola.
OX   NCBI_TaxID=1841481 {ECO:0000313|Ensembl:ENSSLDP00000016271.1, ECO:0000313|Proteomes:UP000261360};
RN   [1] {ECO:0000313|Ensembl:ENSSLDP00000016271.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC   -!- SIMILARITY: Belongs to the SNTX/VTX toxin family.
CC       {ECO:0000256|ARBA:ARBA00006480}.
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DR   AlphaFoldDB; A0A3B4XJ57; -.
DR   Ensembl; ENSSLDT00000016868.1; ENSSLDP00000016271.1; ENSSLDG00000012739.1.
DR   GeneTree; ENSGT00390000014380; -.
DR   Proteomes; UP000261360; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR   GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.120.920; -; 1.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR043136; B30.2/SPRY_sf.
DR   InterPro; IPR003879; Butyrophylin_SPRY.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR006574; PRY.
DR   InterPro; IPR003877; SPRY_dom.
DR   InterPro; IPR048997; Stonustoxin-like_helical.
DR   InterPro; IPR040581; Thioredoxin_11.
DR   PANTHER; PTHR31594; AIG1-TYPE G DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR31594:SF16; FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF13765; PRY; 1.
DR   Pfam; PF00622; SPRY; 1.
DR   Pfam; PF21109; Stonustoxin_helical; 1.
DR   Pfam; PF18078; Thioredoxin_11; 1.
DR   PRINTS; PR01407; BUTYPHLNCDUF.
DR   SMART; SM00589; PRY; 1.
DR   SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR   PROSITE; PS50188; B302_SPRY; 1.
PE   3: Inferred from homology;
KW   Cytolysis {ECO:0000256|ARBA:ARBA00022852};
KW   Hemolysis {ECO:0000256|ARBA:ARBA00022735};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525};
KW   Toxin {ECO:0000256|ARBA:ARBA00022656}.
FT   DOMAIN          508..689
FT                   /note="B30.2/SPRY"
FT                   /evidence="ECO:0000259|PROSITE:PS50188"
SQ   SEQUENCE   689 AA;  78426 MW;  7AE8F053C5507A97 CRC64;
     MASDQMVVAA LGRPFTLGML YDAQKDQLIT AFTQWDKKTI QENSKKHLQQ TSAYEITASD
     SFESKSSLLG IEASLKASFL SGLVEVGGSA SYLNDKKKSN KQSRVTFQYK ATTLFEQLTM
     THPEDKNMQE KEVHEDCSAT HVVTGILYGA NAFFVFDSKK VDASDVQNIQ GSMEAMVKKI
     PSFTCEGKVD IKLSDEEKAL TEKFSCKFYG DFILESNPVT FEDAVKTYQQ LPKLLGENGE
     KTVPVKVWLT PLKKLDSSAP ELKRKICVGL LRKVENALES MMEIQVRCND SLEDEVVKNF
     PQITKKLSNF KDVCDDYTTK LRRTMKEKFP SIRAGNEVDS SVEKLFDNKE KSPFSHENLS
     KWLNNEERKI NVIRSCVELE EIKIVQNKSE LDREVFDRHV DDVLCFVFTS LETAEPYLVQ
     MYDYLHSHDP QCVGSVPPQT QDQWYFSQEV LNKMREKASY FHGLAKALKS SSRFRFHVAV
     VPNEKYKGAT IYHYRNGTLV TEDFSKPAVP DVKTVTDRRD LLWYACDLNL DPDTANGYLS
     LSEGNKKATC GTWQTYPDRR QRFDTRPQVL CREGLTGQQY WEVEWSEGGY NEVGVGLTYG
     EIERKGNGAD TGLGCNSLSW YFGVKEKFEA WHNGHVWSKD LPPTGCRRVG VFLDCCAGSL
     SFYNITHNTL SCLRWSEVVR GCLRWSEVV
//