ID A0A3B4XNK8_SERLL Unreviewed; 842 AA.
AC A0A3B4XNK8;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Interferon-induced GTP-binding protein Mx {ECO:0000256|ARBA:ARBA00015210};
DE EC=3.6.5.5 {ECO:0000256|ARBA:ARBA00011980};
DE AltName: Full=Interferon-inducible Mx protein {ECO:0000256|ARBA:ARBA00031810};
OS Seriola lalandi dorsalis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Carangiformes; Carangidae; Seriola.
OX NCBI_TaxID=1841481 {ECO:0000313|Ensembl:ENSSLDP00000019760.1, ECO:0000313|Proteomes:UP000261360};
RN [1] {ECO:0000313|Ensembl:ENSSLDP00000019760.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class dynamin-like GTPase
CC superfamily. Dynamin/Fzo/YdjA family. {ECO:0000256|RuleBase:RU003932}.
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DR AlphaFoldDB; A0A3B4XNK8; -.
DR STRING; 1841481.ENSSLDP00000019760; -.
DR Ensembl; ENSSLDT00000020425.1; ENSSLDP00000019760.1; ENSSLDG00000015469.1.
DR GeneTree; ENSGT00940000155764; -.
DR Proteomes; UP000261360; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR CDD; cd08771; DLP_1; 1.
DR CDD; cd01256; PH_dynamin; 1.
DR Gene3D; 1.20.120.1240; Dynamin, middle domain; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR022812; Dynamin.
DR InterPro; IPR001401; Dynamin_GTPase.
DR InterPro; IPR019762; Dynamin_GTPase_CS.
DR InterPro; IPR045063; Dynamin_N.
DR InterPro; IPR000375; Dynamin_stalk.
DR InterPro; IPR030381; G_DYNAMIN_dom.
DR InterPro; IPR003130; GED.
DR InterPro; IPR020850; GED_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR11566; DYNAMIN; 1.
DR PANTHER; PTHR11566:SF23; DYNAMIN-2; 1.
DR Pfam; PF01031; Dynamin_M; 1.
DR Pfam; PF00350; Dynamin_N; 1.
DR Pfam; PF02212; GED; 1.
DR Pfam; PF00169; PH; 1.
DR PRINTS; PR00195; DYNAMIN.
DR SMART; SM00053; DYNc; 1.
DR SMART; SM00302; GED; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS00410; G_DYNAMIN_1; 1.
DR PROSITE; PS51718; G_DYNAMIN_2; 1.
DR PROSITE; PS51388; GED; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Endocytosis {ECO:0000256|ARBA:ARBA00022583};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|RuleBase:RU003932};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU003932}.
FT DOMAIN 28..294
FT /note="Dynamin-type G"
FT /evidence="ECO:0000259|PROSITE:PS51718"
FT DOMAIN 516..621
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 650..741
FT /note="GED"
FT /evidence="ECO:0000259|PROSITE:PS51388"
FT REGION 740..842
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 769..806
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 827..842
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 842 AA; 94122 MW; 1F83F3BAA46EB901 CRC64;
MGNRGMEDLI PLINKLQDAF SSIGQSCNLD LPQIAVVGGQ SAGKSSVLEN FVGRDFLPRG
SGIVTRRPLI LQLVNSKAEY AEFLHCKGRK FVDFDEVRLE IEAETDRLTG SNKGISPIPI
NLRVYSPNVL NLTLIDLPGM TKVAVGDQPV DIEHQIRDML LQFITKESCL ILAVTPANTD
LANSDALKIA KEVDPQGLRT IGVITKLDLM DEGTDARDIL ENKLLPLRRG YIGVVNRSQK
DIDGKKDIGA ALAAERKFFL SHPAYRHIAE RMGTPHLQKT LNQQLTNHIR DTLPGLRSKL
QSQMLSLEKE VDEYKNFRAD DPARKTKALL QMVQQFGVDF EKCIEGSGDQ VDTSNLSGGA
KINRIFHERF PFELVKMEFD EKELRKEISY AIKNIHGVRT GLFTPDLAFE AIVKKQIIKL
KEPCLKCIDL VIQELINTVR QCTNKLGSYP RLREETEKIV TTYIRERDSK TKDQVLLLID
IELSYINTNH EDFIGFANAQ QRTAANATKK RVMPNQVIRR GWLTINISIM KGGSKDYWFV
LTAESLSWYK DEEEKEKKYM LPLDNLKLRD VEKGFMSSKH VFAIFNTEQR NVYKDLRQIE
LACDTQEDVD SWKASFLRAG VYPEKDQPEN ADALNPSDTV SMDPQLERQV ETIRNLVDSY
IGIVNKSIRD LMPKTIMHLM INSAKDFIHS ELLAYLYSAG DQGSLMEESA EQAQRRDEML
RMYHALKEAL VIIGDISTTT ISTPVPPPVD DTWIEPSPQQ ASRPASATAA PPSRPPGVRG
PTPGPAPPLN PSPAFGVPPV PSRPGPPLGQ TAYANDPNSS AVPLVPSRPA RVPPALPPGI
PR
//
