ID A0A3B4XP37_SERLL Unreviewed; 1092 AA.
AC A0A3B4XP37;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=DAB2 interacting protein {ECO:0000313|Ensembl:ENSSLDP00000019950.1};
OS Seriola lalandi dorsalis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Carangiformes; Carangidae; Seriola.
OX NCBI_TaxID=1841481 {ECO:0000313|Ensembl:ENSSLDP00000019950.1, ECO:0000313|Proteomes:UP000261360};
RN [1] {ECO:0000313|Ensembl:ENSSLDP00000019950.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3B4XP37; -.
DR Ensembl; ENSSLDT00000020619.1; ENSSLDP00000019950.1; ENSSLDG00000015561.1.
DR GeneTree; ENSGT00940000155853; -.
DR Proteomes; UP000261360; Unplaced.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR CDD; cd04013; C2_SynGAP_like; 1.
DR CDD; cd05136; RasGAP_DAB2IP; 1.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR021887; DAB2P_C.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR039360; Ras_GTPase.
DR InterPro; IPR023152; RasGAP_CS.
DR InterPro; IPR001936; RasGAP_dom.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR PANTHER; PTHR10194:SF26; DISABLED HOMOLOG 2-INTERACTING PROTEIN; 1.
DR PANTHER; PTHR10194; RAS GTPASE-ACTIVATING PROTEINS; 1.
DR Pfam; PF00168; C2; 1.
DR Pfam; PF12004; DAB2P_C; 1.
DR Pfam; PF00616; RasGAP; 2.
DR SMART; SM00239; C2; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00323; RasGAP; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50004; C2; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS00509; RAS_GTPASE_ACTIV_1; 1.
DR PROSITE; PS50018; RAS_GTPASE_ACTIV_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468}.
FT DOMAIN 1..127
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 118..236
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 296..488
FT /note="Ras-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50018"
FT REGION 580..604
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 642..743
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 766..905
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 938..997
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1034..1061
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 642..678
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 770..788
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 801..904
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1092 AA; 122063 MW; B23B2846B95FB3BF CRC64;
SVSLHQGFLS RRLKGSIKRT KSQPKLDRNS SFRHILPGFR SVDNDRSHLM PRLKESRSHE
SLLSPSSAVE ALDLSMEDEV IIKPVHSSIL GQDYCFEVTT STGSKCFSCR SSAERDKWME
NLRRAVQPNK DNSRRVENML RLWIIEAKDL PAKKKYFCEL CLDDSLYART TCKLKTDNVF
WGEHFEFNNL PAIKSITAHL YKDTDKKKKK DKNNYIGLVN IPVAAVTGRQ FVEKWYPVST
PNPPKGKTSG PMIRIKARYQ SMNILPMEMY KEFAEYTTNN YMLLCSVLEP GISVKNKEEM
ACALVHILQS TGKAKDFLTD LMMSEVDRCG ENEHLIFREN TLATKAIEEY LKLVGQKYLQ
DALGEFIKAL YESDENCEVD PSKCSSGDLP EHQSNLKMCC ELAFCKIINS YCVFPRELKE
VFASWRQECS NRGRPDISER LISASLFLRF LCPAIMSPSL FNLMQEYPDD RTARTLTLIA
KVTQNLANFT KFGNKEEYMS FMNQFLEHEW TNMQRFLLEI SNPETISNTA GFEGYIDLGR
ELSTLHSLLS EVVSQMDQSA ASKLGPLPRI LREVNTALSN PSSVQMTPGP ASEHMGSPPA
EASCSISTGL QKMVIDNDLS GLVDFTRLPS PTPENKDLFF VTRSSGIQPS PARSSSYSET
NEPDLGMANG SKSLSMVDLQ DPRSLEGVPG PSTSDALGEC PASGGGWSAR VPQGNILGGP
TLRRPGQPPT TPGTESTPGR PAQLLAPLSF QNPVYQMAAC LPVSPRGMTD SGSECHSSVS
SHSNNEDGPA GGKHTFLNPG DFNRRQLSLT ETPHQPTVPR QNSAGPQRRI DQPPPQSITR
GRTPPNLLNS GPYPRPSSGS MMTSSPDWPG SGARLRQQSS SSKGDSPETK QRAQHKQAPS
PVNPSALDRT AAWLLNMNVQ YLDHEGMEPE SLRNREDLTQ VEKEIAVLQE KLRASVQKLE
EYEARLKGQD EQAQKVLMEY QARLEESEER LRRQQDDKDL QMKGIISRLM SVEEELKKDH
SDMQAVVDSK QKIIDAQEKR IASLDAANAR LMSALTQLKE RYSMQTRNGI SPTNPTKLQI
TENGEFRNSS NC
//
