ID   A0A3B4XSR3_SERLL        Unreviewed;       135 AA.
AC   A0A3B4XSR3;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=E3 SUMO-protein ligase NSE2 {ECO:0000256|ARBA:ARBA00020923};
DE   AltName: Full=E3 SUMO-protein transferase NSE2 {ECO:0000256|ARBA:ARBA00031731};
DE   AltName: Full=Non-structural maintenance of chromosomes element 2 homolog {ECO:0000256|ARBA:ARBA00032533};
OS   Seriola lalandi dorsalis.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Carangaria; Carangiformes; Carangidae; Seriola.
OX   NCBI_TaxID=1841481 {ECO:0000313|Ensembl:ENSSLDP00000019002.1, ECO:0000313|Proteomes:UP000261360};
RN   [1] {ECO:0000313|Ensembl:ENSSLDP00000019002.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- PATHWAY: Protein modification; protein sumoylation.
CC       {ECO:0000256|ARBA:ARBA00004718}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the NSE2 family.
CC       {ECO:0000256|ARBA:ARBA00008212}.
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DR   AlphaFoldDB; A0A3B4XSR3; -.
DR   Ensembl; ENSSLDT00000019644.1; ENSSLDP00000019002.1; ENSSLDG00000014749.1.
DR   GeneTree; ENSGT00940000164859; -.
DR   UniPathway; UPA00886; -.
DR   Proteomes; UP000261360; Unplaced.
DR   GO; GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0030915; C:Smc5-Smc6 complex; IEA:InterPro.
DR   GO; GO:0019789; F:SUMO transferase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IEA:InterPro.
DR   GO; GO:0016925; P:protein sumoylation; IEA:UniProtKB-UniPathway.
DR   CDD; cd16651; SPL-RING_NSE2; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR026846; Nse2(Mms21).
DR   InterPro; IPR004181; Znf_MIZ.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR21330:SF1; E3 SUMO-PROTEIN LIGASE NSE2; 1.
DR   PANTHER; PTHR21330; UNCHARACTERIZED; 1.
DR   Pfam; PF11789; zf-Nse; 1.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   PROSITE; PS51044; ZF_SP_RING; 1.
PE   3: Inferred from homology;
KW   Chromosome {ECO:0000256|ARBA:ARBA00022895};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Telomere {ECO:0000256|ARBA:ARBA00022895};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00452}.
FT   DOMAIN          44..130
FT                   /note="SP-RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51044"
SQ   SEQUENCE   135 AA;  14916 MW;  AF7B7D6876BD110B CRC64;
     MSLSAVHGTL TSLKSCQADI GTGMDIVTDV AMDLAESAEN LEELDEDIAV TLSQVNFTCP
     LTQVEMVNPV KNKKCNHHYD EGAILGLIKT RQSQKKKCRC PVVGCGNADV RESDLIPDQM
     LRRKIQSQKR NNNRT
//