ID A0A3B4XUS8_SERLL Unreviewed; 570 AA.
AC A0A3B4XUS8;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Cyclic nucleotide gated channel subunit alpha 3 {ECO:0000313|Ensembl:ENSSLDP00000019405.1};
GN Name=CNGA3 {ECO:0000313|Ensembl:ENSSLDP00000019405.1};
OS Seriola lalandi dorsalis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Carangiformes; Carangidae; Seriola.
OX NCBI_TaxID=1841481 {ECO:0000313|Ensembl:ENSSLDP00000019405.1, ECO:0000313|Proteomes:UP000261360};
RN [1] {ECO:0000313|Ensembl:ENSSLDP00000019405.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR AlphaFoldDB; A0A3B4XUS8; -.
DR STRING; 1841481.ENSSLDP00000019405; -.
DR Ensembl; ENSSLDT00000020056.1; ENSSLDP00000019405.1; ENSSLDG00000015216.1.
DR GeneTree; ENSGT00940000158737; -.
DR Proteomes; UP000261360; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR CDD; cd00038; CAP_ED; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 1.20.5.300; -; 1.
DR Gene3D; 1.10.287.630; Helix hairpin bin; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR InterPro; IPR032406; CLZ_dom.
DR InterPro; IPR018488; cNMP-bd_CS.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR PANTHER; PTHR45638:SF6; CYCLIC NUCLEOTIDE-GATED CATION CHANNEL ALPHA-3; 1.
DR PANTHER; PTHR45638; CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A; 1.
DR Pfam; PF16526; CLZ; 1.
DR Pfam; PF00027; cNMP_binding; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR SMART; SM00100; cNMP; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
DR PROSITE; PS00888; CNMP_BINDING_1; 1.
DR PROSITE; PS00889; CNMP_BINDING_2; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Sensory transduction {ECO:0000256|ARBA:ARBA00022606};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 59..79
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 197..219
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 270..293
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 374..480
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT REGION 1..46
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 514..566
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 570 AA; 66419 MW; DA7A94100CF3E917 CRC64;
MDIYSKKDDK KDEKKDDKKD EKKDDKKDDK KDDKKNDKKD DKKEEPKEVW IMDPSTDLYY
YWLCTVSIPV FYNLMLLVAR ACFNELQYAN TTQWMVLDYI SDALYYFDTF VRARTGFLDQ
GLLVRDANVL KEKYMKTRQF RLDIISMIPT DIVFLKIGMD NPEWRFNRLF KLARLFEFFD
RTETRTNFPN IFRIGNLVLY IIIIIHWNAC LYFAFSKILG LGSDTWVYPD FKKDPEFARL
ARQYIYCFYW STLTLTTIGE TPPPVRDIEY FFVVVDFLTG VLIFATIVGN VGAMISNMGA
ARVEFQSKID SIKQYMQFRK VTKDLEVRVV KWFDYLWTED KTCDEKQVLK NLPDKLKAEI
AINVHLETLS KVRIFQDCEA GLLIELVLKL QPQVFSPGDY ICKKGDIGRE MYIIKEGKLA
VVADDGVTQF VVLSDGAYFG EISILGIKGS KAGNRRTANI RSVGYSDLFA LSKDDLMEAL
TEYPDAKYAL EDKGRAILMK DNLIDMSLAS IVDAKDLENK VNQIEASYEI MSTKFRKLSN
QYESSQRKMK QRLTNLSNQV RTLRVDDDDE
//
