ID   A0A3B4XY47_SERLL        Unreviewed;       670 AA.
AC   A0A3B4XY47;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Small conductance calcium-activated potassium channel protein 2-like {ECO:0000313|Ensembl:ENSSLDP00000020738.1};
GN   Name=KCNN2 {ECO:0000313|Ensembl:ENSSLDP00000020738.1};
OS   Seriola lalandi dorsalis.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Carangaria; Carangiformes; Carangidae; Seriola.
OX   NCBI_TaxID=1841481 {ECO:0000313|Ensembl:ENSSLDP00000020738.1, ECO:0000313|Proteomes:UP000261360};
RN   [1] {ECO:0000313|Ensembl:ENSSLDP00000020738.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   AlphaFoldDB; A0A3B4XY47; -.
DR   STRING; 1841481.ENSSLDP00000020738; -.
DR   Ensembl; ENSSLDT00000021431.1; ENSSLDP00000020738.1; ENSSLDG00000016208.1.
DR   GeneTree; ENSGT00950000182904; -.
DR   Proteomes; UP000261360; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR   GO; GO:0016286; F:small conductance calcium-activated potassium channel activity; IEA:InterPro.
DR   Gene3D; 1.10.287.70; -; 2.
DR   InterPro; IPR004178; CaM-bd_dom.
DR   InterPro; IPR036122; CaM-bd_dom_sf.
DR   InterPro; IPR015449; K_chnl_Ca-activ_SK.
DR   InterPro; IPR013099; K_chnl_dom.
DR   PANTHER; PTHR10153; SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL; 1.
DR   PANTHER; PTHR10153:SF43; SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL PROTEIN 2; 1.
DR   Pfam; PF02888; CaMBD; 1.
DR   Pfam; PF07885; Ion_trans_2; 1.
DR   Pfam; PF03530; SK_channel; 1.
DR   PRINTS; PR01451; SKCHANNEL.
DR   SMART; SM01053; CaMBD; 1.
DR   SUPFAM; SSF81327; Small-conductance potassium channel; 1.
DR   SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE   4: Predicted;
KW   Calmodulin-binding {ECO:0000256|ARBA:ARBA00022860};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   DOMAIN          507..583
FT                   /note="Calmodulin-binding"
FT                   /evidence="ECO:0000259|SMART:SM01053"
FT   REGION          89..123
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          153..174
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          192..211
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          639..670
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          588..615
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        157..174
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        653..670
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   670 AA;  75651 MW;  7FF025CB98239FD2 CRC64;
     METPLQLQND FFPEQQFQHC KYQHYCGRED RLVKQHDQCC TCNNCTCDAR KSLVFRGTSP
     TTVGTLRTPS ETSSRQGCQY SVCEFTPSSH GSSSRHHHPH HQQQHCRDRQ RGSLGSSHKD
     SNSYNEIAMS SCRYNGGVMR PLSNLSSSRR NIHEFDSESQ PLQPISAADA SDTLVSKPEN
     NSTTLMPYAS GDGGGGCSHS GGKSGKKKNQ NIGEKLGHRR ALFEKRKRLS DYALIFGMFG
     IVVMVIETEL SWGAYGKESL YSLALKCLIS LSTIILLGLI IIYHAREIQL FMVDNAADDW
     RIAMTYERIF FICLEILVCA IHPIPGNYTF TWTARLAYSY VPSKTDADVD IILSIPMFLR
     LYLIARVMLL HSKLFTDASS RSIGALNKIN FNTRFVMKTL MTICPGTVLL VFTISLWIIA
     AWTVRACERY HDNQDITSNF LGAMWLISIT FLTIGYGDMV PNTYCGKGVC LLTGIMGAGC
     TALVVAVVAK KLELTKAEKH VHNFMMDTQL TKRVKNTAAN VLRETWLIYK NTKLVRKMDH
     ARVRKHQRKF LQAIHQLRSV KMEQRKLNDQ ANSLVDLAKT QNIMYDMISD LNERGEDMEK
     RIALLETKLE TLLSNLQALP GLISQVISQQ HRDFLEVQLQ PYDKHSPERS QSVSRRRSSS
     TAPPTSSESS
//