ID   A0A3B4Y0Z3_SERLL        Unreviewed;       514 AA.
AC   A0A3B4Y0Z3;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Acid-sensing ion channel 1C-like {ECO:0000313|Ensembl:ENSSLDP00000017153.1};
OS   Seriola lalandi dorsalis.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Carangaria; Carangiformes; Carangidae; Seriola.
OX   NCBI_TaxID=1841481 {ECO:0000313|Ensembl:ENSSLDP00000017153.1, ECO:0000313|Proteomes:UP000261360};
RN   [1] {ECO:0000313|Ensembl:ENSSLDP00000017153.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
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DR   AlphaFoldDB; A0A3B4Y0Z3; -.
DR   Ensembl; ENSSLDT00000017759.1; ENSSLDP00000017153.1; ENSSLDG00000013563.1.
DR   GeneTree; ENSGT00940000164727; -.
DR   Proteomes; UP000261360; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015280; F:ligand-gated sodium channel activity; IEA:InterPro.
DR   Gene3D; 1.10.3590.10; acid-sensing ion channel 1 domain; 2.
DR   Gene3D; 1.10.287.820; Acid-sensing ion channel domain; 1.
DR   Gene3D; 1.10.287.770; YojJ-like; 2.
DR   InterPro; IPR001873; ENaC.
DR   InterPro; IPR004724; ENaC_chordates.
DR   InterPro; IPR020903; ENaC_CS.
DR   NCBIfam; TIGR00859; ENaC; 1.
DR   PANTHER; PTHR11690:SF252; ACID-SENSING ION CHANNEL 1C; 1.
DR   PANTHER; PTHR11690; AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED; 1.
DR   Pfam; PF00858; ASC; 1.
DR   PRINTS; PR01078; AMINACHANNEL.
DR   PROSITE; PS01206; ASC; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Ion channel {ECO:0000256|ARBA:ARBA00022461};
KW   Ion transport {ECO:0000256|ARBA:ARBA00022461};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Sodium {ECO:0000256|ARBA:ARBA00023053};
KW   Sodium channel {ECO:0000256|ARBA:ARBA00022461};
KW   Sodium transport {ECO:0000256|ARBA:ARBA00023201};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022461}.
FT   TRANSMEM        43..61
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   514 AA;  58475 MW;  430CB2B1055DC5B9 CRC64;
     MKGSSEESIE SIRPSNLQAF ANISTLHGMS HIFAYGHMTF RRFLWTLSFL GSLGLLMLVC
     MDRVSYYLEY PHVTKLDEVA ATNLTFPAVT FCNLNEFRFS KITRNDLYHV GELLALLNNN
     YQIANPHLAE PEVLAALKDK ANFQNFKPKL FNMTDFYNRT GHDISDMLLQ CTFRGEDCYP
     VNFTTIYTRY GKCYTFNSGL DGNPLLTTLK GGTGNGLEIM LDIQQDEYLP VWGETDETSY
     EAGIKVQLHS QSEPPFLHEL GFGVAPGFQT FVSTQEQRLQ YLPPPWGDCK STPIDSEYFS
     TYSITACRID CETRYLLENC NCRMVHMPGT STVCTPEQYK DCADPALDFL VEKDNDYCVC
     QTPCNMTRYG KELSMVKIPS KASAKYLAKK FNKTEQYIGE NILVLDIFFE ALNYEKIEQK
     KAYEIAGLLG DIGGQMGLFI GASVLTILEI FDYLYEVFKD KVLGYFIRKK RPQRCQSDNL
     STCDTLRSHS DSLGFTPNML PRHPTLGNFE EFAC
//