ID   A0A3B4Y264_SERLL        Unreviewed;       842 AA.
AC   A0A3B4Y264;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   SubName: Full=Potassium voltage-gated channel subfamily KQT member 5-like {ECO:0000313|Ensembl:ENSSLDP00000022126.1};
GN   Name=KCNQ5 {ECO:0000313|Ensembl:ENSSLDP00000022126.1};
OS   Seriola lalandi dorsalis.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Carangaria; Carangiformes; Carangidae; Seriola.
OX   NCBI_TaxID=1841481 {ECO:0000313|Ensembl:ENSSLDP00000022126.1, ECO:0000313|Proteomes:UP000261360};
RN   [1] {ECO:0000313|Ensembl:ENSSLDP00000022126.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
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DR   AlphaFoldDB; A0A3B4Y264; -.
DR   STRING; 1841481.ENSSLDP00000022126; -.
DR   Ensembl; ENSSLDT00000022846.1; ENSSLDP00000022126.1; ENSSLDG00000017263.1.
DR   GeneTree; ENSGT00940000155933; -.
DR   Proteomes; UP000261360; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR   Gene3D; 1.10.287.70; -; 1.
DR   Gene3D; 6.10.140.1910; -; 1.
DR   Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 1.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR003937; K_chnl_volt-dep_KCNQ.
DR   InterPro; IPR013821; K_chnl_volt-dep_KCNQ_C.
DR   InterPro; IPR027359; Volt_channel_dom_sf.
DR   PANTHER; PTHR47735; POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 4; 1.
DR   PANTHER; PTHR47735:SF8; POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 5; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF03520; KCNQ_channel; 1.
DR   PRINTS; PR00169; KCHANNEL.
DR   PRINTS; PR01459; KCNQCHANNEL.
DR   SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE   4: Predicted;
KW   Calmodulin-binding {ECO:0000256|ARBA:ARBA00022860};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        108..130
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        136..161
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        182..202
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        250..269
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        307..333
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          108..337
FT                   /note="Ion transport"
FT                   /evidence="ECO:0000259|Pfam:PF00520"
FT   DOMAIN          396..505
FT                   /note="Potassium channel voltage dependent KCNQ C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF03520"
FT   REGION          528..700
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          750..779
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          800..842
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        579..609
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        671..687
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        750..775
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        804..818
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        828..842
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   842 AA;  92192 MW;  44573F3B8DF73C1D CRC64;
     MPRSHTGDES GGTGLWLKTS TGRRAQDYAL KDVESGRMTM NNAVRVNDGL LSPATAGAVG
     AERKQGARLS LLGKPLTYSA QSGRRNARYR RLQNYLYNVL ERPREWAFIY HAFVFILVFG
     CLVLSVFSTI PAHQEFSSHC LLILEFVMIV VFGLEYIIRI WSAGCCCRYR GWQGRLRFAR
     KPFCVIDIIV LIASVAVVSA GSQGNIFATS ALRSLRFLQI LRMVRMDRRG GTWKLLGSVV
     YAHSKELVTA WYIGFLVLIF SSFLVYLVEK EFNKEFATYA DALWWGTITL TTIGYGDKTP
     QTWTGRLLSA GFALLGISFF ALPAGILGSG FALKVQEQHR QKHFEKRRNP AASLIQCVWR
     SYAADENSVS IATWKPHLKA LHTCSPAKKE QGETTYRIMK FHVAKKKFKE TLRPYDVKDV
     IEQYSAGHLD MLCRIKSLQT RVDQILGKGQ IPVDKKMRDK LNPDGDSLEG MSMLGRVCKV
     ERQVTSIESK LDSLLDVYRQ VLQKGSSALT LSSLPLFELD SQRHRSSDYQ TSIIGRDLPS
     PQGGDPVRGG GDNSGGLCRS LSANPKGLRL ILAPADDDGP PDSAPPSYPP STASLSPSPL
     LPPDSPYPTL VTPNGTSKRA HFPDLPPPPP STGGFTLQLP PMVHPSHLRC PADSIPDDLT
     DGVTADKKSL GPSVVGSSVN ADQEGDSEAG SVQGGVQLRE KPALKSEGVW RRHMSLEVNP
     LLLLSSSPDE RPSDWEGGLG KSLSVHNLSQ PLTSRAPGLN NSNSSSSNGS ERGNAHGDLS
     NWDGTELFIS ECKLEPAEEH FNFLSQGPDS SPSDLLQTVD EAASGPKGNS EFLSQSPHIQ
     LA
//