ID   A0A3B4YBL4_SERLL        Unreviewed;       646 AA.
AC   A0A3B4YBL4;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   SubName: Full=RAP1 GTPase activating protein 2 {ECO:0000313|Ensembl:ENSSLDP00000025561.1};
OS   Seriola lalandi dorsalis.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Carangaria; Carangiformes; Carangidae; Seriola.
OX   NCBI_TaxID=1841481 {ECO:0000313|Ensembl:ENSSLDP00000025561.1, ECO:0000313|Proteomes:UP000261360};
RN   [1] {ECO:0000313|Ensembl:ENSSLDP00000025561.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3B4YBL4; -.
DR   STRING; 1841481.ENSSLDP00000025561; -.
DR   Ensembl; ENSSLDT00000026352.1; ENSSLDP00000025561.1; ENSSLDG00000019688.1.
DR   GeneTree; ENSGT00940000165230; -.
DR   Proteomes; UP000261360; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
DR   Gene3D; 6.10.140.210; -; 1.
DR   Gene3D; 3.40.50.11210; Rap/Ran-GAP; 1.
DR   InterPro; IPR035974; Rap/Ran-GAP_sf.
DR   InterPro; IPR000331; Rap/Ran_GAP_dom.
DR   PANTHER; PTHR15711; RAP GTPASE-ACTIVATING PROTEIN; 1.
DR   PANTHER; PTHR15711:SF17; RAP1 GTPASE-ACTIVATING PROTEIN 2; 1.
DR   Pfam; PF21022; Rap-GAP_dimer; 1.
DR   Pfam; PF02145; Rap_GAP; 1.
DR   SUPFAM; SSF111347; Rap/Ran-GAP; 1.
DR   PROSITE; PS50085; RAPGAP; 1.
PE   4: Predicted;
KW   GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        47..67
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          215..431
FT                   /note="Rap-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50085"
FT   REGION          92..118
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          479..622
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        501..522
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        567..582
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        599..622
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   646 AA;  71529 MW;  589FC63829DA1B16 CRC64;
     MSHSYTRNTH LHPSHVFQHK AFEALRSFAT THDYQACVMK VLFLRDIVFY SILSFVCLPS
     ALLPKVLEKG GPYPQVILPQ FGGYWIEDVE APAGTPSSSE SSFCEEEDRE EGMSPGGGHS
     YRLECNSTAR AYRKHFLGKE HMNYYCTGSS IGNLIMSLKH EDAEGQEFLR IMLRSRTKTV
     HDRISLAGIS QLPSVPQIAK QEIVVFVSVQ GSQLIVAYDE HEVNNTFKFG VIYQKFGQTS
     EEELFGNNEE TPAFKEFLSI LGDNIELQDF KGFRGGLDVS HGQTGSESVY TVFRQREIMF
     HVSTKLPFTE GDVQQLQRKR HIGNDIVAAV FQEESTPFVP DMIASNFLHA YVLVQVENPC
     TEHTTYKVSV TAREDVPSFG PPLPNPAVFK KGPEFRDFLL TKLINAENAC YKSDKFAKLE
     GRTRAALLDN LHDELHRQSQ ATLGLGQAGE EDKLENGGHG GLLESFKRAM RVRSHSMETM
     VGSHRHRSPG VGGGVPASLS GGGLPQSTSE CTKSTFTPPG LSAKSPLKSP VKRRSGLFPR
     LHSSTESPSD RHSRSDQKPA EICPLSQEVR SETSSNPSSP EICPNKERPF IKLKECSSGR
     PNISRSSSST SSFSSTTGET EALEDLETVT EASVFSSVPL FQLFTL
//