ID   A0A3B4YBT0_SERLL        Unreviewed;       444 AA.
AC   A0A3B4YBT0;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=E2F transcription factor 2 {ECO:0000313|Ensembl:ENSSLDP00000025443.1};
OS   Seriola lalandi dorsalis.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Carangaria; Carangiformes; Carangidae; Seriola.
OX   NCBI_TaxID=1841481 {ECO:0000313|Ensembl:ENSSLDP00000025443.1, ECO:0000313|Proteomes:UP000261360};
RN   [1] {ECO:0000313|Ensembl:ENSSLDP00000025443.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU003796}.
CC   -!- SIMILARITY: Belongs to the E2F/DP family.
CC       {ECO:0000256|ARBA:ARBA00010940, ECO:0000256|RuleBase:RU003796}.
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DR   AlphaFoldDB; A0A3B4YBT0; -.
DR   STRING; 1841481.ENSSLDP00000025443; -.
DR   Ensembl; ENSSLDT00000026234.1; ENSSLDP00000025443.1; ENSSLDG00000019795.1.
DR   GeneTree; ENSGT00940000155115; -.
DR   Proteomes; UP000261360; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005667; C:transcription regulator complex; IEA:InterPro.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR   CDD; cd14660; E2F_DD; 1.
DR   Gene3D; 6.10.250.540; -; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR015633; E2F.
DR   InterPro; IPR037241; E2F-DP_heterodim.
DR   InterPro; IPR032198; E2F_CC-MB.
DR   InterPro; IPR003316; E2F_WHTH_DNA-bd_dom.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR12081; TRANSCRIPTION FACTOR E2F; 1.
DR   PANTHER; PTHR12081:SF50; TRANSCRIPTION FACTOR E2F2; 1.
DR   Pfam; PF16421; E2F_CC-MB; 1.
DR   Pfam; PF02319; E2F_TDP; 1.
DR   SMART; SM01372; E2F_TDP; 1.
DR   SUPFAM; SSF144074; E2F-DP heterodimerization region; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU003796};
KW   Nucleus {ECO:0000256|RuleBase:RU003796};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163,
KW   ECO:0000256|RuleBase:RU003796};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW   ECO:0000256|RuleBase:RU003796}.
FT   DOMAIN          131..196
FT                   /note="E2F/DP family winged-helix DNA-binding"
FT                   /evidence="ECO:0000259|SMART:SM01372"
FT   REGION          111..132
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   444 AA;  48192 MW;  3FB8451A32C7A208 CRC64;
     MMRMPKGVSP ASCRPAVGLS CPQQKVKVLS KTELLGTVLS SPPMNTVPVG YFTQICNTTA
     AEQRANSLYS TPHGPEAKPI RSSSGRLPAK RKLDLEDPLY LPEFRTPKGK GIITTRVPSP
     RTPKSPGERT RYDTSLGLLT KKFVGLIAES PDGVLDLNWA TEVLEVQKRR IYDITNVLEG
     VQLIRKKSKN NIQWLVGDVF EGGAGGGEKA CALRKELGDL ERAERSLDEL IHSSTTQLKQ
     LTEYKDNQRF GYVTYQDIRS IGSLRDQTVI AVKAPAETKL EVPDTAGQGS LQIYLKSKNG
     PIEVYLCPEE GLEDASPVKS AVTPKKEFPQ PLCPPAVTPV APPSYTIKEE PVECAMSTAA
     PTTSSAAASS SSLLDVEGLL GLPPSLLQIT EDQLPGTSFT PDPNTPFVSF SPPLDHNDYL
     WSLEDGEGVS DFFDTYDLGD LLSS
//