ID A0A3B4YH40_SERLL Unreviewed; 882 AA.
AC A0A3B4YH40;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Extracellular calcium-sensing receptor-like {ECO:0000313|Ensembl:ENSSLDP00000028947.1};
OS Seriola lalandi dorsalis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Carangiformes; Carangidae; Seriola.
OX NCBI_TaxID=1841481 {ECO:0000313|Ensembl:ENSSLDP00000028947.1, ECO:0000313|Proteomes:UP000261360};
RN [1] {ECO:0000313|Ensembl:ENSSLDP00000028947.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR AlphaFoldDB; A0A3B4YH40; -.
DR STRING; 1841481.ENSSLDP00000028947; -.
DR Ensembl; ENSSLDT00000029794.1; ENSSLDP00000028947.1; ENSSLDG00000022357.1.
DR GeneTree; ENSGT00940000162782; -.
DR Proteomes; UP000261360; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR CDD; cd15283; 7tmC_V2R_pheromone; 1.
DR CDD; cd06364; PBP1_CaSR; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 2.10.50.30; GPCR, family 3, nine cysteines domain; 1.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR000337; GPCR_3.
DR InterPro; IPR011500; GPCR_3_9-Cys_dom.
DR InterPro; IPR038550; GPCR_3_9-Cys_sf.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR000068; GPCR_3_Ca_sens_rcpt-rel.
DR InterPro; IPR017979; GPCR_3_CS.
DR InterPro; IPR004073; GPCR_3_vmron_rcpt_2.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR24061:SF418; C-FAMILY ODORANT RECEPTOR OLFCQ19-RELATED; 1.
DR PANTHER; PTHR24061; CALCIUM-SENSING RECEPTOR-RELATED; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF07562; NCD3G; 1.
DR PRINTS; PR00248; GPCRMGR.
DR PRINTS; PR01535; VOMERONASL2R.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00981; G_PROTEIN_RECEP_F3_3; 1.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 612..637
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 649..671
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 683..707
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 728..748
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 768..796
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 808..828
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 840..863
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 613..878
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
SQ SEQUENCE 882 AA; 97702 MW; F2894C6304E883B0 CRC64;
MAVMGANLNT FSLLYVYLML ILFSSTFFTS ESSSLFSTCK LRRQFYLNGM HKPGDVILGG
LFEVHYTSVF PELTFTSEPN QLSCRGFDPP GFRHAMTMAF AIDEINKNSN LLPNVTLGYS
LYDNCATLVI GFSAALSLAS GREEQFLFQE TCLGTPPVLG IVGDSFSTFS IATSDVIGLF
RLPIVSYFAT CSCLSDRQRF PSFFRTIPSD AFQVRAMIQI LKRFGWTWAG LLVSDDDYGL
HVSRSFQSDL AQSGGGCLAY TEILPWGDNP AELRRIVNVM KKSTARVVIV FAHQIHMIQL
MEEVVRQNVT GLQWMASEAW TAAAVLQTPH LMPYLGGTLG IAIRRGEIPG LRDFLSGIRP
DFHDNNNNGN SLFWEYTFQC RFAPAPAGWI EAGGALCTGN EDLENVETEF LDVSNLRPEY
NIYKAVYALA YALDDMLLCE AGRGPFSGHS CATLKTLEPW QLMYYLEKVN FTTPFGDEVS
FDGNGDALPI YDIMNWLWLP DGRTKVQNVG VVKKSPFKGE ELTLHEDKIF WNFDSKQPPR
SACSESCPPG TRMARKKGEP VCCFDCVPCS EGKISNETDS MECISCPEDF WSSPQRDHCV
PKKTEFLSYH EPLGICLTVT SLLGTFICAV VLGIFIYHRS TPMVRANNSE LSFLLLVSLK
LCFLCSLLFI GRPRLWTCQL RHAAFGISFV LCVSCILVKT MVVLAVFKAS KPGGGASLKW
FGAVQQRGTV LVLTSVQAAI CIAWLVSSSP APHKNTQYHN DKIVYECVIG STIGFAVLLG
YIGLLAILSF LLAFLARNLP DNFNEAKLIT FSMLIFCAVW VAFVPAYVNS PGKYADAVEV
FAILASSFGL LVALFGPKCY IILLRPERNT KKAIMGRGTS KT
//
