ID A0A3B4YIX4_SERLL Unreviewed; 1031 AA.
AC A0A3B4YIX4;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=Integrin subunit alpha 9 {ECO:0000313|Ensembl:ENSSLDP00000028068.1};
OS Seriola lalandi dorsalis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Carangiformes; Carangidae; Seriola.
OX NCBI_TaxID=1841481 {ECO:0000313|Ensembl:ENSSLDP00000028068.1, ECO:0000313|Proteomes:UP000261360};
RN [1] {ECO:0000313|Ensembl:ENSSLDP00000028068.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479,
CC ECO:0000256|RuleBase:RU003762}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004479, ECO:0000256|RuleBase:RU003762}.
CC -!- SIMILARITY: Belongs to the integrin alpha chain family.
CC {ECO:0000256|ARBA:ARBA00008054, ECO:0000256|RuleBase:RU003762}.
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DR AlphaFoldDB; A0A3B4YIX4; -.
DR STRING; 1841481.ENSSLDP00000028068; -.
DR Ensembl; ENSSLDT00000028909.1; ENSSLDP00000028068.1; ENSSLDG00000021690.1.
DR GeneTree; ENSGT00940000156503; -.
DR OrthoDB; 3816176at2759; -.
DR Proteomes; UP000261360; Unplaced.
DR GO; GO:0008305; C:integrin complex; IEA:InterPro.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR GO; GO:0001946; P:lymphangiogenesis; IEA:Ensembl.
DR Gene3D; 1.20.5.930; Bicelle-embedded integrin alpha(iib) transmembrane segment; 1.
DR Gene3D; 2.130.10.130; Integrin alpha, N-terminal; 1.
DR Gene3D; 2.60.40.1460; Integrin domains. Chain A, domain 2; 1.
DR Gene3D; 2.60.40.1510; ntegrin, alpha v. Chain A, domain 3; 1.
DR Gene3D; 2.60.40.1530; ntegrin, alpha v. Chain A, domain 4; 1.
DR InterPro; IPR013517; FG-GAP.
DR InterPro; IPR013519; Int_alpha_beta-p.
DR InterPro; IPR000413; Integrin_alpha.
DR InterPro; IPR018184; Integrin_alpha_C_CS.
DR InterPro; IPR013649; Integrin_alpha_Ig-like_1.
DR InterPro; IPR048285; Integrin_alpha_Ig-like_2.
DR InterPro; IPR048286; Integrin_alpha_Ig-like_3.
DR InterPro; IPR028994; Integrin_alpha_N.
DR InterPro; IPR032695; Integrin_dom_sf.
DR PANTHER; PTHR23220; INTEGRIN ALPHA; 1.
DR PANTHER; PTHR23220:SF69; INTEGRIN ALPHA-9; 1.
DR Pfam; PF01839; FG-GAP; 2.
DR Pfam; PF08441; Integrin_A_Ig_1; 1.
DR Pfam; PF20805; Integrin_A_Ig_2; 1.
DR Pfam; PF20806; Integrin_A_Ig_3; 1.
DR PRINTS; PR01185; INTEGRINA.
DR SMART; SM00191; Int_alpha; 5.
DR SUPFAM; SSF69318; Integrin alpha N-terminal domain; 1.
DR SUPFAM; SSF69179; Integrin domains; 3.
DR PROSITE; PS51470; FG_GAP; 5.
DR PROSITE; PS00242; INTEGRIN_ALPHA; 1.
PE 3: Inferred from homology;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889,
KW ECO:0000256|RuleBase:RU003762};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Integrin {ECO:0000256|ARBA:ARBA00023037, ECO:0000256|RuleBase:RU003762};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU003762};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|RuleBase:RU003762};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU003762};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU003762}.
FT TRANSMEM 974..998
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU003762"
FT REPEAT 33..98
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT REPEAT 235..289
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT REPEAT 290..349
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT REPEAT 350..408
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT REPEAT 413..474
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT DOMAIN 459..619
FT /note="Integrin alpha first immunoglubulin-like"
FT /evidence="ECO:0000259|Pfam:PF08441"
FT DOMAIN 621..761
FT /note="Integrin alpha second immunoglobulin-like"
FT /evidence="ECO:0000259|Pfam:PF20805"
FT DOMAIN 770..947
FT /note="Integrin alpha third immunoglobulin-like"
FT /evidence="ECO:0000259|Pfam:PF20806"
SQ SEQUENCE 1031 AA; 114613 MW; 4698C71DFBFB7419 CRC64;
MMRKGMATLR RQKTGVQNVF YVFLSISVAY SYNIDLEHPL VFRGPNSSFF GYSVLEHYHD
NTRWVIVGAP RANSTYSSSV HSPGAVYKCR VHSNPERRCT EMDLGRGNKL RESCGKTCQG
DRDDEWMGVS LARQDRADGK ILACAHRWKN VYYDSEHILP HGYCSIIPPT LQGRTKPLIP
CYEDYKQKYG EEHGSCQAGI AGVFTEELVV MGAPGSYYWT GTIKVYNLTS DSFYSPNKED
VDSHRYSYLG YAVTAGHFSS PNVIDIAAGA PQHSGSGKVY IFKIDGVSLV KSFQASGKMM
GSYFGSSLCA VDLNQDGLSD LLVGAPMHSQ LRDEGQVSVY LSKGNGVMEE GGVLTGDNAF
NAHFGESIAA IGDIDDDGYQ DVAIGAPKED DYGGAVYIYH GDATGIISKY SMKLSGRSVN
PGLQMFGQSI SGNVDMDSNG YTDVTIGAFM ADSVVLLRSR PVITVDVSIF LPVSINISVP
QCHEGHHNLN CFNVTVCMRF RGRQVPGQIE LLYNLTADVD KRQKSQPSRV YFIQGGSQIS
QMSHQLSLDV NREECQRYTA YVKKDVKDVF TAITFEVAYS LGKHVLTGHQ ERDLPALTPV
LRWRKGNKIA VRNETWFEKN CLSDDCAADL RLHGKLLLSG VHSKPHLALG GVKNVSLNLT
ISNAGDDAYD TNIYFNFSRE VFYINFWQKE EKGISCELVD LDFLKCSVGF PFMRAQTKYH
FAVIFDTSQL SGVNDTLQFL VQAKSANPEH KLSDNSLDLS IALVHETDTT ITGVVTPSSF
VYGNSIDASR FVQLEDMECN FQPLNLTFQA INKGPSRLPG STVDIRIPNR LAGNGADMFH
IIETQVAEGR GNCTPHRNPT PCTIPQDKES IFHSIFAFFT KSGRKVLDCD RPGRACMTIS
CSLGPQLKEE ALSIDIKLLL NTEILKRDSS SVIQFVTRGS VQVNDKAMEV PKGLPEDISL
VFEALHSQEP RGYVVGWIIA ISLLVGILIF LLLAVLLWKM GFFRRRYREI IEAEKNRKDS
DESWDWMEKN H
//
