ID A0A3B4YJ72_SERLL Unreviewed; 685 AA.
AC A0A3B4YJ72;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=EPS8 like 2 {ECO:0000313|Ensembl:ENSSLDP00000029677.1};
GN Name=EPS8L2 {ECO:0000313|Ensembl:ENSSLDP00000029677.1};
OS Seriola lalandi dorsalis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Carangiformes; Carangidae; Seriola.
OX NCBI_TaxID=1841481 {ECO:0000313|Ensembl:ENSSLDP00000029677.1, ECO:0000313|Proteomes:UP000261360};
RN [1] {ECO:0000313|Ensembl:ENSSLDP00000029677.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the EPS8 family.
CC {ECO:0000256|ARBA:ARBA00006197}.
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DR AlphaFoldDB; A0A3B4YJ72; -.
DR STRING; 1841481.ENSSLDP00000029677; -.
DR Ensembl; ENSSLDT00000030539.1; ENSSLDP00000029677.1; ENSSLDG00000022901.1.
DR GeneTree; ENSGT00940000160990; -.
DR OrthoDB; 2997036at2759; -.
DR Proteomes; UP000261360; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR CDD; cd01210; PTB_EPS8; 1.
DR CDD; cd09540; SAM_EPS8-like; 1.
DR CDD; cd11764; SH3_Eps8; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR039801; EPS8-like.
DR InterPro; IPR033928; EPS8_PTB.
DR InterPro; IPR035462; Eps8_SH3.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR013625; PTB.
DR InterPro; IPR006020; PTB/PI_dom.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR041418; SAM_3.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR12287:SF20; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE 8-LIKE PROTEIN 2; 1.
DR PANTHER; PTHR12287; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE EPS8-RELATED PROTEIN; 1.
DR Pfam; PF08416; PTB; 1.
DR Pfam; PF18016; SAM_3; 1.
DR Pfam; PF00018; SH3_1; 1.
DR SMART; SM00462; PTB; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS01179; PID; 1.
DR PROSITE; PS50002; SH3; 1.
PE 3: Inferred from homology;
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 49..168
FT /note="PID"
FT /evidence="ECO:0000259|PROSITE:PS01179"
FT DOMAIN 465..524
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 189..236
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 422..462
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 212..227
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 448..462
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 685 AA; 77469 MW; 8035297C6C7DD721 CRC64;
MPEIMSVLEP QTRQANGVAR SDSKISAKAL YEQRKKYSNS NFIMHETSQY HVEHLSTFIM
DKTESIVTVD DAIKKLVLLD SKDKIWTQEM LLQVTDNAVR LLDCDTQEEL ENFPLPTIHM
CQTVLNQTRY TSVLLLVCQD KEQHKPDIHF FHCDEVEAEM VHADVDSAIG DNKHGKKMRL
QTLKVNQEKM KRHRETILPP SVPKGPSRSP KGRVAATSTQ ARQAPGQNDT ESHEKLAQRI
EKDVQILNCA LDDIEIFVAQ VQKAAEAFSQ LNHRNKSKKN KKRGPAEGML TLRAKPPSEA
EFIDSLQKLK LALNLLAKLK KHIQNPSASE LVHFLFGPLE LVLQSFGSPE VPRSVISPHL
SKDAVEFLRG HLSPKELTIF ELLGEGWTKP RAEWSRDQCA PPYYPKFRNG WEPPMELFRT
APWETEGPTG LGSPSSPDYR KHSAEDFYGT HSSSSSNGSY NGKTHTRKYA KIRYHFVARN
ANELSVLQDE ILEVIEDDKQ WWKLRNRSGQ AGYVPFNILD VVKIEEPEGN YSQQGYRTSP
PGSVSHGDSF NMGIQKDKMM DDVTSELLMM ITANKSQPPA RKFRVERSSG SQVPLAFDSN
PEQVTAWLNA KGFSKPTVEC LGILTGAQLF SLNKEELKAV CGDEGSRVYC QVTVQKTQLE
QTNGDSELQE IMRRRQERID SGSKD
//
