ID A0A3B4YLM4_SERLL Unreviewed; 822 AA.
AC A0A3B4YLM4;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Discs large MAGUK scaffold protein 3 {ECO:0000313|Ensembl:ENSSLDP00000029053.1};
GN Name=DLG3 {ECO:0000313|Ensembl:ENSSLDP00000029053.1};
OS Seriola lalandi dorsalis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Carangiformes; Carangidae; Seriola.
OX NCBI_TaxID=1841481 {ECO:0000313|Ensembl:ENSSLDP00000029053.1, ECO:0000313|Proteomes:UP000261360};
RN [1] {ECO:0000313|Ensembl:ENSSLDP00000029053.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3B4YLM4; -.
DR Ensembl; ENSSLDT00000029899.1; ENSSLDP00000029053.1; ENSSLDG00000022378.1.
DR GeneTree; ENSGT00940000159565; -.
DR Proteomes; UP000261360; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0031594; C:neuromuscular junction; IEA:InterPro.
DR GO; GO:0043005; C:neuron projection; IEA:InterPro.
DR GO; GO:0019900; F:kinase binding; IEA:InterPro.
DR GO; GO:0007268; P:chemical synaptic transmission; IEA:InterPro.
DR CDD; cd00071; GMPK; 1.
DR CDD; cd00992; PDZ_signaling; 3.
DR CDD; cd12029; SH3_DLG3; 1.
DR Gene3D; 2.30.42.10; -; 3.
DR Gene3D; 3.30.63.10; Guanylate Kinase phosphate binding domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR019583; DLG1-4_PDZ_assoc.
DR InterPro; IPR016313; DLG1-like.
DR InterPro; IPR035763; DLG3_SH3.
DR InterPro; IPR008145; GK/Ca_channel_bsu.
DR InterPro; IPR008144; Guanylate_kin-like_dom.
DR InterPro; IPR020590; Guanylate_kinase_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR23119; DISCS LARGE; 1.
DR PANTHER; PTHR23119:SF28; DISKS LARGE HOMOLOG 3; 1.
DR Pfam; PF00625; Guanylate_kin; 1.
DR Pfam; PF00595; PDZ; 3.
DR Pfam; PF10600; PDZ_assoc; 1.
DR Pfam; PF00018; SH3_1; 1.
DR PIRSF; PIRSF001741; MAGUK_DLGH; 1.
DR SMART; SM00072; GuKc; 1.
DR SMART; SM00228; PDZ; 3.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 3.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS00856; GUANYLATE_KINASE_1; 1.
DR PROSITE; PS50052; GUANYLATE_KINASE_2; 1.
DR PROSITE; PS50106; PDZ; 3.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 134..221
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 229..316
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 384..465
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 499..569
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 632..807
FT /note="Guanylate kinase-like"
FT /evidence="ECO:0000259|PROSITE:PS50052"
FT REGION 41..108
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 93..108
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 822 AA; 90535 MW; 4BF233257CF45313 CRC64;
MHKHHHCCKC PECYEVTRMA ALRRMDAPSY GGDWQAEPYG YPPGYGGGQT LPPPASGGGG
SMGGGGGTLG RSKGKIMSSG GPGGPNPKGQ SKGGPKVNGS NSSGQGGWWP ECTCTNREWY
DQVNGSDGMY KYEEIILERG NSGLGFSIAG GIDNPHIPDD PGIFITKIIP GGAAAMDGRL
GVNDCVLRVN DVDVSEVVHS RAVEALKEAG PVVRLLVRRR QAPPETILEV NLLKGPKGLG
FSIAGGIGNQ HIPGDNSIYI TKIIEGGAAQ KDGRLQTGDR LLAVNNIMLQ DVRHEEAVAA
LKNTSDMVYL KVAKPGPVHL NDMYAPPDYS STFPTMVDNH VSHNYMGAME PKPVYPPPQV
TPSRYSPVPR PVLGEDDFTR EPRKVLLHKG STGLGFNIVG GEDGEGIFVS FILAGGPADL
SGELRRGDRI LSVNGVNLRN ATHEQAAAAL KRAGQTVTII AQYRPEEYSR FESKIHDLRE
QMMNSSMSSG SGSLRTSEKR SLYVRALFDY DRTRDSCLPS QGLSFSYGDI LHVINASDDE
WWQARLVTPH GESEQIGVIP SKKRVEKKER ARLKTVKFHA RTGMIESNRV SVEDQLLPVL
VPERLSSELL LEGQEDTILS YEPVIRQEIH YTRPVIILGP MKDRINDDLI SEFPHKFGSC
VPHTTRPRRE NEMDGQDYHF VASREQMEKD IQDNKFIEAG QFNENLYGTS ILSVRTVAER
GKHCILDVSG NAIKRLQQAQ LYPIAIFIKP KSIEALMEMN KRQTYEQANK VFDKAVKLEQ
DFGEYFTAIV QGDSLEEIYN KIKLIIEEQS GPYIWIPSSE KL
//
