ID   A0A3B4YMA2_SERLL        Unreviewed;       918 AA.
AC   A0A3B4YMA2;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Extracellular calcium-sensing receptor-like {ECO:0000313|Ensembl:ENSSLDP00000029303.1};
OS   Seriola lalandi dorsalis.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Carangaria; Carangiformes; Carangidae; Seriola.
OX   NCBI_TaxID=1841481 {ECO:0000313|Ensembl:ENSSLDP00000029303.1, ECO:0000313|Proteomes:UP000261360};
RN   [1] {ECO:0000313|Ensembl:ENSSLDP00000029303.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
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DR   AlphaFoldDB; A0A3B4YMA2; -.
DR   STRING; 1841481.ENSSLDP00000029303; -.
DR   Ensembl; ENSSLDT00000030157.1; ENSSLDP00000029303.1; ENSSLDG00000022526.1.
DR   GeneTree; ENSGT00940000162782; -.
DR   Proteomes; UP000261360; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR   CDD; cd15283; 7tmC_V2R_pheromone; 1.
DR   CDD; cd06364; PBP1_CaSR; 1.
DR   Gene3D; 3.40.50.2300; -; 2.
DR   Gene3D; 2.10.50.30; GPCR, family 3, nine cysteines domain; 1.
DR   InterPro; IPR001828; ANF_lig-bd_rcpt.
DR   InterPro; IPR000337; GPCR_3.
DR   InterPro; IPR011500; GPCR_3_9-Cys_dom.
DR   InterPro; IPR038550; GPCR_3_9-Cys_sf.
DR   InterPro; IPR017978; GPCR_3_C.
DR   InterPro; IPR000068; GPCR_3_Ca_sens_rcpt-rel.
DR   InterPro; IPR017979; GPCR_3_CS.
DR   InterPro; IPR004073; GPCR_3_vmron_rcpt_2.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   PANTHER; PTHR24061:SF418; C-FAMILY ODORANT RECEPTOR OLFCQ19-RELATED; 1.
DR   PANTHER; PTHR24061; CALCIUM-SENSING RECEPTOR-RELATED; 1.
DR   Pfam; PF00003; 7tm_3; 1.
DR   Pfam; PF01094; ANF_receptor; 1.
DR   Pfam; PF07562; NCD3G; 1.
DR   PRINTS; PR00248; GPCRMGR.
DR   PRINTS; PR01535; VOMERONASL2R.
DR   SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR   PROSITE; PS00981; G_PROTEIN_RECEP_F3_3; 1.
DR   PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000256|ARBA:ARBA00023170};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        648..673
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        685..707
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        719..743
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        764..784
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        804..832
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        844..864
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        876..899
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          649..914
FT                   /note="G-protein coupled receptors family 3 profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50259"
SQ   SEQUENCE   918 AA;  102266 MW;  A38B25E33ACD3FA5 CRC64;
     MPGWVERFNN DRKHAKGWHS PAHKTKNPCV KNRKRCEGRR EVMGGFLDSY LLLCVCLTLV
     FCCSPSLCSV SSSPPSSCKL RRKFHLNGMH KPGDVVLGGL FEVHYTSVFP EWTFTSEPQQ
     PSCKGFDTLG FRHAMTMAFA IDEINKNSNL LPNLTLGYSL YDNCGALIIG FSGALSLASG
     QVDQFLLQDN CLGTPPVLGI VGDHYSTFSI AISNVLGLYK IPTVSYFATC SCLSDRQRFP
     SFFRTIPSDA FQILKHFGWT WVGLLVSDDD YGLHVAQSLQ SDLAQSGGGC LAYLEVLPWD
     SDPSELKRIV YLIKTSTARV VIVFAHEIHM IQLMEEVVRQ NVTGLQWIAS EAWTSAAVLQ
     TPRFMPYLSG TLGIAIRRGE IPGLRAFLLQ IRPDLHHNNS YGNSMVRQFW EYTFQCRFAP
     PPAGWIEVGG KSCTGDEDIG NVETEFLDLS NLRPEYNVYK AVYALVYALD NILQCEPGRG
     PFSEHSCATL KTLEPWQLLH YLQKVNFTTP FGDQVSFDEN GDASPIYDIM NWLWLPDGRI
     KVQNVGEVKK SVFKGEELTL DEDKIFWNFE SKEPPRSVCS ESCPPGTRMA RKKGEPECCF
     DCIPCSEGKI SNSTDSMKCT SCPEDFWSSP QRDYCVPKKT EFLSYHEPLG ICLTTTSLLG
     TFICAVVLGI FIYHRSTPMV RANNSELSFL LLVSLKLCFL CSLLFIGRPR LWTCQLRHAA
     FGISFVLCVS CILVKTMVVL AVFKASKPGG GASLKWFGAV QQRGTVLALT CIQAVICTAW
     LVSASTAPHK NTEYHNDKIV YECVVGSTIG FAVLLGYIGF LAILSFLLAF LARNLPDNFN
     EAKFITFSML IFCAVWVAFV PAYVNSPGKY ADAVEVFAIL ASSFGLLVAL FGPKCYIILL
     RPEKNTKKAI MGREKRKS
//