ID A0A3B4YRB6_SERLL Unreviewed; 843 AA.
AC A0A3B4YRB6;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Neurocan {ECO:0008006|Google:ProtNLM};
OS Seriola lalandi dorsalis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Carangiformes; Carangidae; Seriola.
OX NCBI_TaxID=1841481 {ECO:0000313|Ensembl:ENSSLDP00000030761.1, ECO:0000313|Proteomes:UP000261360};
RN [1] {ECO:0000313|Ensembl:ENSSLDP00000030761.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR AlphaFoldDB; A0A3B4YRB6; -.
DR STRING; 1841481.ENSSLDP00000030761; -.
DR Ensembl; ENSSLDT00000031647.1; ENSSLDP00000030761.1; ENSSLDG00000023679.1.
DR GeneTree; ENSGT00940000158649; -.
DR Proteomes; UP000261360; Unplaced.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0005540; F:hyaluronic acid binding; IEA:InterPro.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 2.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR Gene3D; 3.10.100.10; Mannose-Binding Protein A, subunit A; 2.
DR InterPro; IPR001304; C-type_lectin-like.
DR InterPro; IPR016186; C-type_lectin-like/link_sf.
DR InterPro; IPR016187; CTDL_fold.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR000538; Link_dom.
DR PANTHER; PTHR22804; AGGRECAN/VERSICAN PROTEOGLYCAN; 1.
DR PANTHER; PTHR22804:SF24; NEUROCAN CORE PROTEIN; 1.
DR Pfam; PF00008; EGF; 2.
DR Pfam; PF00059; Lectin_C; 1.
DR Pfam; PF00193; Xlink; 1.
DR PRINTS; PR01265; LINKMODULE.
DR SMART; SM00034; CLECT; 1.
DR SMART; SM00181; EGF; 2.
DR SMART; SM00179; EGF_CA; 2.
DR SMART; SM00445; LINK; 1.
DR SUPFAM; SSF56436; C-type lectin-like; 2.
DR SUPFAM; SSF57196; EGF/Laminin; 1.
DR PROSITE; PS00010; ASX_HYDROXYL; 1.
DR PROSITE; PS50041; C_TYPE_LECTIN_2; 1.
DR PROSITE; PS00022; EGF_1; 2.
DR PROSITE; PS01186; EGF_2; 1.
DR PROSITE; PS50026; EGF_3; 2.
DR PROSITE; PS01187; EGF_CA; 1.
DR PROSITE; PS01241; LINK_1; 1.
DR PROSITE; PS50963; LINK_2; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Glycoprotein {ECO:0000256|ARBA:ARBA00022974};
KW Proteoglycan {ECO:0000256|ARBA:ARBA00022974}.
FT DOMAIN 12..105
FT /note="Link"
FT /evidence="ECO:0000259|PROSITE:PS50963"
FT DOMAIN 671..707
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 709..745
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 758..829
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT REGION 132..163
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 207..228
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 253..601
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 622..643
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 268..362
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 364..378
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 387..420
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 436..456
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 457..601
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 55..76
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00323"
FT DISULFID 697..706
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 735..744
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 843 AA; 89646 MW; 318BD6A1E4A24112 CRC64;
QAPVSCLPPP GEVFHSSVPG RLSLSSASDR CVSLGGQLAT VGQLYLAWRA GLDSCAPGWL
SDGSVRYPVT WPRPECGGSQ PGVCTVTPNS TADNTTALYD AYCYRGKVKN TGSISQIYTS
LWKPWSYLTG SSDADSTGTD KPDLTTQQTF TTRGSSDASP SNWTGLVDLE EEAALHNADA
STDPWSSESS GSYLTLQLIP GQSSLDWGEL LEPGPDSEEF LRPPVHPTPA EKKVISKIVK
SIWKPWNYLV GTGDEEGTRA PNGQAGEEDT ATAKTEPSNT SSPGLLSWGS SWFSSTPEEN
ASSASEDSPT RLASTLAASG IPTTTESTKS WESSETHTFT ASSSAPEITA SSGDTWVRVE
AETTTQPGEK REETVTSRAS GRGGRGRGKK NRGEDRSRGE ERGRGEEKGK GEDEGSGEIT
GAEAKGEIQV SRRPVGTSKP RERSRERSRE RGHRKGQSTT TTTTATTTAS PPEPTVMTTP
GSESADFSTS KSPSALPAET PSPSISLDPY QTLSSSPSPS TSPSPSISAF MSFSQSSPSQ
SPSLSFSSSP SPSTDAPLST SQTPSLSPSP ASPSSQSSTQ MVGSGDPSPS PLSENQDSAT
NPLTSLHWVP VEKVSHNSSL DYPPLLSGPS DEEEPAWSHA VGSGALLPGN MDEESSRGSN
ISTITLGQTM EVEPCVTNPC LHGGKCLPQG TGYSCYCPQG YTGENCEIDV DDCQSEPCEN
GGTCIDKIDA FLCLCLPSYG GDTCEKDIEG CEHGWRKFHG HCYRYFTHRH TWEDAEKDCR
EHSAHLSSVI SATEQEFING LGHDNAWIGL NDRTVEEDFQ WTDGNDLVSD RRSVVPPTAN
HQL
//
