ID A0A3B4YRF1_SERLL Unreviewed; 2072 AA.
AC A0A3B4YRF1;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Dedicator of cytokinesis protein 9-like {ECO:0000313|Ensembl:ENSSLDP00000032327.1};
OS Seriola lalandi dorsalis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Carangiformes; Carangidae; Seriola.
OX NCBI_TaxID=1841481 {ECO:0000313|Ensembl:ENSSLDP00000032327.1, ECO:0000313|Proteomes:UP000261360};
RN [1] {ECO:0000313|Ensembl:ENSSLDP00000032327.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the DOCK family. {ECO:0000256|PROSITE-
CC ProRule:PRU00983}.
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DR Ensembl; ENSSLDT00000033245.1; ENSSLDP00000032327.1; ENSSLDG00000021358.1.
DR GeneTree; ENSGT00940000155972; -.
DR Proteomes; UP000261360; Unplaced.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd08697; C2_Dock-D; 1.
DR CDD; cd11698; DHR2_DOCK9; 1.
DR CDD; cd13267; PH_DOCK-D; 1.
DR Gene3D; 1.20.58.740; -; 1.
DR Gene3D; 1.25.40.410; -; 1.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR037809; C2_Dock-D.
DR InterPro; IPR027007; C2_DOCK-type_domain.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR026791; DOCK.
DR InterPro; IPR021816; DOCK_C/D_N.
DR InterPro; IPR043161; DOCK_C_lobe_A.
DR InterPro; IPR043162; DOCK_C_lobe_C.
DR InterPro; IPR027357; DOCKER_dom.
DR InterPro; IPR046769; DOCKER_Lobe_A.
DR InterPro; IPR046770; DOCKER_Lobe_B.
DR InterPro; IPR046773; DOCKER_Lobe_C.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR23317; DEDICATOR OF CYTOKINESIS DOCK; 1.
DR PANTHER; PTHR23317:SF77; DEDICATOR OF CYTOKINESIS PROTEIN 9; 1.
DR Pfam; PF06920; DHR-2_Lobe_A; 1.
DR Pfam; PF20422; DHR-2_Lobe_B; 1.
DR Pfam; PF20421; DHR-2_Lobe_C; 1.
DR Pfam; PF14429; DOCK-C2; 1.
DR Pfam; PF11878; DOCK_C-D_N; 1.
DR Pfam; PF00169; PH; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS51650; C2_DOCK; 1.
DR PROSITE; PS51651; DOCKER; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}.
FT DOMAIN 169..276
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 638..811
FT /note="C2 DOCK-type"
FT /evidence="ECO:0000259|PROSITE:PS51650"
FT DOMAIN 1616..2043
FT /note="DOCKER"
FT /evidence="ECO:0000259|PROSITE:PS51651"
FT REGION 285..307
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1227..1260
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 2013..2040
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 285..302
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2072 AA; 235172 MW; 36D4F761123C960F CRC64;
MASAPPEARK FTRGLNKPGT AAELRQSVSE AVRTSVLMVK PKIIEPLDYE NVLLQRKTQI
ISDVLRDMLQ FPTDDFQIST LRRQGRTLFS TVPETAEKEA DSLFVQECIK TYKSDWHVVN
YKYEEYSGDF RQLPNKVLRP EKLAAHLFEV DEDVEKDEDT ASLGSQKGGV SKHGWLYKGN
MNSAISVTMR SFKRRYFHLA QLGDGSYNLN FYKDENTSKE PKGTIFLDSC MGVVQNSKVR
RFAFELKMQD KSTFLLAADS EAEMEEWITT LNKILHSSFE QAMQEKRNGD LHDDEEHGKT
DLSSGSFQDS FQTARDIESK MRSEARLKLF TLDPYTQKLD FSGIEPDVRQ FEEKFGKRVL
VSCNDLSFNL QGCVAENEEG PTTNVEPFYV VLSLFDVQNS RKISADFHVD LNHPLVRQMT
SGSGSGQELQ INGSRDDGLL GGCRLASGLP EGALDYPRQG VFSVTCPHPD IFLVARVEKV
LQGGITHCTE PYMKSSDSAK MAQKVLKNAK TACSRLGQYR MPFAWAARPV FKDASGTLDK
SARFSALYRQ DSSKLSDEDM FKLLTDFRKP EKMAKLPVLL GNLDVTIDSV APDVTNCVTS
SYIPVRNFEG NGPGSALLEV EEFVPCIAKC SQPFTIYKNH LYVYPKLLKY DGQKSFAKAR
NIAVCIEFKD SDEDEAQPLK CIYGRPGAPL FTKQAYAAIL HHQQNPEFYD EIKIELPTQL
HEKHHLLFTF YHVSCDSNSK KKDQVETPVG SAWLPLLRDG RVIMNEQQLS VAANLPAGYL
GSQDGVTKHS ASEIKWVDGG KPLFKVSTHL VSTVYTQDQH LHNFFHHCQN MEMSEQASEG
ELVKYLKSLH AMEGHVMVNF LPTVLNQLFC VLTRATHEDV AVNVTRVMVH VVAQCHEEGL
EHYLRSYVKF VFKPEPYSST NVKTVHEELA KAMTAILKPS TDFLTSNKLL KHSWFFFEAL
VKSVAHYLME SGKVKLSRNQ RFSASFYHSV ETLVNMLMPH ITQKYKDNLD AAHNANHSLA
VFIKRCFTFM DRGFVFKQIN NYMNCFMPGD PKTLYEFKFE FLRVVCSHEH YVPLNLPMPF
GKGRIQRFQD LQLDYSLTDD FCRNHFLVGL LLREVGGALQ EFREIRQIAI QVLKGLMIKH
TFDDRYAAKS QQARLATLYL PMFGLLQENV HRLDIKESAP LSNLNNARED SLVQNSMVTP
QKPGSCIENA LHKDVFGVIS GTASPHSSTP NVSSVHHADS RGSLVSTDSG NSLLDKSSEK
TNSLEKNQCA SALGSTVLRC DKLDRDEIKN LLMCFLHILK SMSEEALFAY WNKAASSELM
DFFTLIEVCL HQFRYMGKRF IARSQEGAGP VAPDRKSLTL PVSRNRAGIL HARLQQLGAL
ENSHTFNNMY SHTEADVSSQ CLLEANVSTE VCLTVLDTLS IFIMGFKTQL TSDLGHNPLM
KKVFQVHLCF LQIPQSEAAL KQVFTSLRTF IYKFPCTFFD GRADMCASLC YEILKCCNSK
LSSIRSDAAH LLYFLMKSNF DYTGRRSFVR THLQVVIAVS QLIADVIGIG GTRFQQSLSI
INNCANSDKS IKHTAFPSDV KDLTKRIRTV LMATEQMKEH ENDPEMLVDL QYSLAKSYTS
TPELRKTWLD SMARIHNKNG DLSEAAMCYV HVAALVAEYL WRKGMFRQGC SAFRVITPNI
DEEAAMMEDV GMQDVHFNEE VLMELLEECA DGLWKAERYE LIADVYRLII PIYEQRRDFE
KLTHLYDTLH RAYTKVMEVM HTGKRLLGTF FRVAFFGQGF FEDEDGKEYI YKEPKFTPLS
EISQRLLKLY SDKFGQENVK IIQDSGKVNP KDLDSKYAYI QVTHVTPYLD DKELEDRKTD
FEKSHNIRRF VFETPFTVSG KKQGGVEEQC KRRTVLTTTH CFPYVKKRIA VMYQHQTDLS
PIEVAIDEMS SKVAELRLLC SALEVDMIRL QLKLQGSISV QVNAGPLAYA RAFLDDSSAK
KYPDNKVKQL KEVFRQFVDA CGQALGVNER LIKEDQQEYH DEMKANYKDL TRELSSIMHE
QINPVEDGTR STLSDSMGIF NAISGTPTSG SL
//
