ID A0A3B4YVM1_SERLL Unreviewed; 2067 AA.
AC A0A3B4YVM1;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Dedicator of cytokinesis protein 9-like {ECO:0000313|Ensembl:ENSSLDP00000032251.1};
OS Seriola lalandi dorsalis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Carangiformes; Carangidae; Seriola.
OX NCBI_TaxID=1841481 {ECO:0000313|Ensembl:ENSSLDP00000032251.1, ECO:0000313|Proteomes:UP000261360};
RN [1] {ECO:0000313|Ensembl:ENSSLDP00000032251.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the DOCK family. {ECO:0000256|PROSITE-
CC ProRule:PRU00983}.
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DR Ensembl; ENSSLDT00000033169.1; ENSSLDP00000032251.1; ENSSLDG00000021358.1.
DR GeneTree; ENSGT00940000155972; -.
DR Proteomes; UP000261360; Unplaced.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd08697; C2_Dock-D; 1.
DR CDD; cd11698; DHR2_DOCK9; 1.
DR CDD; cd13267; PH_DOCK-D; 1.
DR Gene3D; 1.20.58.740; -; 1.
DR Gene3D; 1.25.40.410; -; 1.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR037809; C2_Dock-D.
DR InterPro; IPR027007; C2_DOCK-type_domain.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR026791; DOCK.
DR InterPro; IPR021816; DOCK_C/D_N.
DR InterPro; IPR043161; DOCK_C_lobe_A.
DR InterPro; IPR043162; DOCK_C_lobe_C.
DR InterPro; IPR027357; DOCKER_dom.
DR InterPro; IPR046769; DOCKER_Lobe_A.
DR InterPro; IPR046770; DOCKER_Lobe_B.
DR InterPro; IPR046773; DOCKER_Lobe_C.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR23317; DEDICATOR OF CYTOKINESIS DOCK; 1.
DR PANTHER; PTHR23317:SF77; DEDICATOR OF CYTOKINESIS PROTEIN 9; 1.
DR Pfam; PF06920; DHR-2_Lobe_A; 1.
DR Pfam; PF20422; DHR-2_Lobe_B; 1.
DR Pfam; PF20421; DHR-2_Lobe_C; 1.
DR Pfam; PF14429; DOCK-C2; 1.
DR Pfam; PF11878; DOCK_C-D_N; 1.
DR Pfam; PF00169; PH; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS51650; C2_DOCK; 1.
DR PROSITE; PS51651; DOCKER; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}.
FT DOMAIN 168..275
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 637..810
FT /note="C2 DOCK-type"
FT /evidence="ECO:0000259|PROSITE:PS51650"
FT DOMAIN 1611..2038
FT /note="DOCKER"
FT /evidence="ECO:0000259|PROSITE:PS51651"
FT REGION 284..306
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1222..1255
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 2008..2035
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 284..301
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2067 AA; 234670 MW; 768660F35757057A CRC64;
IITPVQARKF TRGLNKPGTA AELRQSVSEA VRTSVLMVKP KIIEPLDYEN VLLQRKTQII
SDVLRDMLQF PTDDFQISTL RRQGRTLFST VPETAEKEAD SLFVQECIKT YKSDWHVVNY
KYEEYSGDFR QLPNKVLRPE KLAAHLFEVD EDVEKDEDTA SLGSQKGGVS KHGWLYKGNM
NSAISVTMRS FKRRYFHLAQ LGDGSYNLNF YKDENTSKEP KGTIFLDSCM GVVQNSKVRR
FAFELKMQDK STFLLAADSE AEMEEWITTL NKILHSSFEQ AMQEKRNGDL HDDEEHGKTD
LSSGSFQDSF QTARDIESKM RSEARLKLFT LDPYTQKLDF SGIEPDVRQF EEKFGKRVLV
SCNDLSFNLQ GCVAENEEGP TTNVEPFYVV LSLFDVQNSR KISADFHVDL NHPLVRQMTS
GSGSGQELQI NGSRDDGLLG GCRLASGLPE GALDYPRQGV FSVTCPHPDI FLVARVEKVL
QGGITHCTEP YMKSSDSAKM AQKVLKNAKT ACSRLGQYRM PFAWAARPVF KDASGTLDKS
ARFSALYRQD SSKLSDEDMF KLLTDFRKPE KMAKLPVLLG NLDVTIDSVA PDVTNCVTSS
YIPVRNFEGN GPGSALLEVE EFVPCIAKCS QPFTIYKNHL YVYPKLLKYD GQKSFAKARN
IAVCIEFKDS DEDEAQPLKC IYGRPGAPLF TKQAYAAILH HQQNPEFYDE IKIELPTQLH
EKHHLLFTFY HVSCDSNSKK KDQVETPVGS AWLPLLRDGR VIMNEQQLSV AANLPAGYLG
SQDGVTKHSA SEIKWVDGGK PLFKVSTHLV STVYTQDQHL HNFFHHCQNM EMSEQASEGE
LVKYLKSLHA MEGHVMVNFL PTVLNQLFCV LTRATHEDVA VNVTRVMVHV VAQCHEEGLE
HYLRSYVKFV FKPEPYSSTN VKTVHEELAK AMTAILKPST DFLTSNKLLK HSWFFFEALV
KSVAHYLMES GKVKLSRNQR FSASFYHSVE TLVNMLMPHI TQKYKDNLDA AHNANHSLAV
FIKRCFTFMD RGFVFKQINN YMNCFMPGDP KTLYEFKFEF LRVVCSHEHY VPLNLPMPFG
KGRIQRFQDL QLDYSLTDDF CRNHFLVGLL LREVGGALQE FREIRQIAIQ VLKGLMIKHT
FDDRYAAKSQ QARLATLYLP MFGLLQENVH RLDIKESAPL SNLNDSLVQN SMVTPQKPGS
CIENALHKDV FGVISGTASP HSSTPNVSSV HHADSRGSLV STDSGNSLLD KSSEKTNSLE
KNQCASALGS TVLRCDKLDR DEIKNLLMCF LHILKSMSEE ALFAYWNKAA SSELMDFFTL
IEVCLHQFRY MGKRFIARSQ EGAGPVAPDR KSLTLPVSRN RAGILHARLQ QLGALENSHT
FNNMYSHTEA DVSSQCLLEA NVSTEVCLTV LDTLSIFIMG FKTQLTSDLG HNPLMKKVFQ
VHLCFLQIPQ SEAALKQVFT SLRTFIYKFP CTFFDGRADM CASLCYEILK CCNSKLSSIR
SDAAHLLYFL MKSNFDYTGR RSFVRTHLQV VIAVSQLIAD VIGIGGTRFQ QSLSIINNCA
NSDKSIKHTA FPSDVKDLTK RIRTVLMATE QMKEHENDPE MLVDLQYSLA KSYTSTPELR
KTWLDSMARI HNKNGDLSEA AMCYVHVAAL VAEYLWRKGM FRQGCSAFRV ITPNIDEEAA
MMEDVGMQDV HFNEEVLMEL LEECADGLWK AERYELIADV YRLIIPIYEQ RRDFEKLTHL
YDTLHRAYTK VMEVMHTGKR LLGTFFRVAF FGQGFFEDED GKEYIYKEPK FTPLSEISQR
LLKLYSDKFG QENVKIIQDS GKVNPKDLDS KYAYIQVTHV TPYLDDKELE DRKTDFEKSH
NIRRFVFETP FTVSGKKQGG VEEQCKRRTV LTTTHCFPYV KKRIAVMYQH QTDLSPIEVA
IDEMSSKVAE LRLLCSALEV DMIRLQLKLQ GSISVQVNAG PLAYARAFLD DSSAKKYPDN
KVKQLKEVFR QFVDACGQAL GVNERLIKED QQEYHDEMKA NYKDLTRELS SIMHEQINPV
EDGTRSTLSD SMGIFNAISG TPTSGSL
//
