ID A0A3B4YWR7_9TELE Unreviewed; 935 AA.
AC A0A3B4YWR7;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Sorting nexin-14-like {ECO:0000313|Ensembl:ENSSPAP00000001173.1, ECO:0000313|RefSeq:XP_008296332.1, ECO:0000313|RefSeq:XP_008296333.1};
GN Name=LOC103369404 {ECO:0000313|RefSeq:XP_008296332.1,
GN ECO:0000313|RefSeq:XP_008296333.1};
OS Stegastes partitus (bicolor damselfish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Stegastes.
OX NCBI_TaxID=144197 {ECO:0000313|Ensembl:ENSSPAP00000001173.1, ECO:0000313|Proteomes:UP000261400};
RN [1] {ECO:0000313|Ensembl:ENSSPAP00000001173.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_008296332.1, ECO:0000313|RefSeq:XP_008296333.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the sorting nexin family.
CC {ECO:0000256|ARBA:ARBA00010883}.
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DR RefSeq; XP_008296332.1; XM_008298110.1.
DR RefSeq; XP_008296333.1; XM_008298111.1.
DR AlphaFoldDB; A0A3B4YWR7; -.
DR STRING; 144197.ENSSPAP00000001173; -.
DR Ensembl; ENSSPAT00000001192.1; ENSSPAP00000001173.1; ENSSPAG00000000817.1.
DR GeneID; 103369404; -.
DR GeneTree; ENSGT00950000182856; -.
DR OrthoDB; 2877434at2759; -.
DR Proteomes; UP000261400; Unplaced.
DR Proteomes; UP000694891; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IEA:InterPro.
DR GO; GO:0097352; P:autophagosome maturation; IEA:Ensembl.
DR GO; GO:0021680; P:cerebellar Purkinje cell layer development; IEA:Ensembl.
DR CDD; cd06877; PX_SNX14; 1.
DR CDD; cd08722; RGS_SNX14; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR Gene3D; 1.10.167.10; Regulator of G-protein Signalling 4, domain 2; 1.
DR InterPro; IPR003114; Phox_assoc.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR016137; RGS.
DR InterPro; IPR036305; RGS_sf.
DR InterPro; IPR044926; RGS_subdomain_2.
DR InterPro; IPR037436; SNX14_PX.
DR InterPro; IPR037892; SNX14_RGS.
DR InterPro; IPR013937; Sorting_nexin_C.
DR PANTHER; PTHR22775; SORTING NEXIN; 1.
DR PANTHER; PTHR22775:SF44; SORTING NEXIN-14; 1.
DR Pfam; PF08628; Nexin_C; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF02194; PXA; 1.
DR Pfam; PF00615; RGS; 1.
DR SMART; SM00312; PX; 1.
DR SMART; SM00313; PXA; 1.
DR SMART; SM00315; RGS; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR SUPFAM; SSF48097; Regulator of G-protein signaling, RGS; 1.
DR PROSITE; PS50195; PX; 1.
DR PROSITE; PS51207; PXA; 1.
DR PROSITE; PS50132; RGS; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000694891};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 27..44
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 51..70
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 128..302
FT /note="PXA"
FT /evidence="ECO:0000259|PROSITE:PS51207"
FT DOMAIN 334..466
FT /note="RGS"
FT /evidence="ECO:0000259|PROSITE:PS50132"
FT DOMAIN 563..683
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
SQ SEQUENCE 935 AA; 107853 MW; A325C15EDC49AEDC CRC64;
MPGIFTYVED LKRGLKVDVL REAGRQYPLS CFLLLSMVLL TVLLNRYIHI LMVFWSLLAG
VITFYCSLGP ESLLPNIFFT VKPRNNRQEQ ELFPLGHSCA VCGKVKCKRH RPTLLLENYQ
PWLDLKVHSK VDASVAEVFE LVLENFVYPW YRDITDDEAC LDEVRMTFRF FASVLVRRAQ
KVDVTTVFAD KVMKAAMKHI EIIAKAQGRV NNVEGLQQAA LDEYGADLHF ALHSRKDELL
YLRKLTEMLF PYVMPPKATD CRSLALLLRE VMAGSVILPT MDFMADPDTV NLMVLIFVDD
TPPEPATEPP SALVPFLQKF ADVGNKKPSV LKLELKEIRE QQDLLFRFMN FLKQEGAVHV
LQFCLAVEEF NDKILSPELS DSELQRLHGE VLHIYETYCL DESIDKISFD PFIVEEIRNI
AKGPYTGVVK LQTMRCLFEA YEHVLSLLER VFTPMFCHSD EYFRHLLRGA ESPARNSRIN
RNSFIMEENR NMSKRGESFG ISRIGSKIKG VFKSTTMEGA LLPPSAMNDI DDDFVEEATV
VMEDESPAEP ASTPGSHRNL SAWTITIPFI DFYDDMVKKE KIPVFCIDVE RNDRKDVGHE
TEKWSVYRRY LEFYVLESKL TEFHGTFADA QLPSKRIIGP KNFEFLTSKR EEFEEYLQRL
LQHPELSNSQ LLADFLSPHS MESQFLDRML PDVNLGKIFK SVPGKLIKER GQNLEPFIQS
FFNSCESPKP KPSRPELTIL SPTAENNKKL FTDLFRNNAN ISVGSEIKQN SNYFMEMVTV
AGMYDYMMYV GRVVFHVPDW LHHMLAAGRI LFKSTFEAYM DQYMQSKLEQ ILQEHRMVSL
ITQLRDAVFC ENSEERRAED KQIRAKQTFE EMMKYLPDFV GKCIGEEAKY EGIQLLFDGL
QQPLLNKQMT YVLLDIAVQE LFPELSKGVR EAIIV
//
