ID   A0A3B4Z099_9TELE        Unreviewed;       470 AA.
AC   A0A3B4Z099;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=UEV and lactate/malate dehyrogenase domains {ECO:0000313|Ensembl:ENSSPAP00000002303.1};
DE   SubName: Full=Ubiquitin-conjugating enzyme E2 variant 3 {ECO:0000313|RefSeq:XP_008291901.1};
GN   Name=uevld {ECO:0000313|RefSeq:XP_008291901.1};
OS   Stegastes partitus (bicolor damselfish).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Stegastes.
OX   NCBI_TaxID=144197 {ECO:0000313|Ensembl:ENSSPAP00000002303.1, ECO:0000313|Proteomes:UP000261400};
RN   [1] {ECO:0000313|Ensembl:ENSSPAP00000002303.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
RN   [2] {ECO:0000313|RefSeq:XP_008291901.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_008291901.1; XM_008293679.1.
DR   AlphaFoldDB; A0A3B4Z099; -.
DR   STRING; 144197.ENSSPAP00000002303; -.
DR   Ensembl; ENSSPAT00000002337.1; ENSSPAP00000002303.1; ENSSPAG00000001762.1.
DR   GeneID; 103366058; -.
DR   CTD; 55293; -.
DR   GeneTree; ENSGT00940000153903; -.
DR   OrthoDB; 5344346at2759; -.
DR   Proteomes; UP000261400; Unplaced.
DR   Proteomes; UP000694891; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   GO; GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
DR   GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:InterPro.
DR   Gene3D; 3.90.110.10; Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   Gene3D; 3.10.110.10; Ubiquitin Conjugating Enzyme; 1.
DR   InterPro; IPR001557; L-lactate/malate_DH.
DR   InterPro; IPR022383; Lactate/malate_DH_C.
DR   InterPro; IPR001236; Lactate/malate_DH_N.
DR   InterPro; IPR015955; Lactate_DH/Glyco_Ohase_4_C.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR   InterPro; IPR008883; UEV_N.
DR   PANTHER; PTHR43128; L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+)); 1.
DR   PANTHER; PTHR43128:SF32; UBIQUITIN-CONJUGATING ENZYME E2 VARIANT 3; 1.
DR   Pfam; PF02866; Ldh_1_C; 1.
DR   Pfam; PF00056; Ldh_1_N; 1.
DR   Pfam; PF05743; UEV; 1.
DR   PRINTS; PR00086; LLDHDRGNASE.
DR   SUPFAM; SSF56327; LDH C-terminal domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   SUPFAM; SSF54495; UBC-like; 1.
DR   PROSITE; PS51322; UEV; 1.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   NAD {ECO:0000256|ARBA:ARBA00023027};
KW   Reference proteome {ECO:0000313|Proteomes:UP000694891}.
FT   DOMAIN          2..145
FT                   /note="UEV"
FT                   /evidence="ECO:0000259|PROSITE:PS51322"
SQ   SEQUENCE   470 AA;  51218 MW;  6130D4B692C853C8 CRC64;
     MDLKSEKIER ILSKYKFHDV AIEELQKIHR IYPGMRPSTG TYTFSDSTQK DLLKLTGNVP
     VKYEGRSYNF PVQLWLMDSF PFTPPICLLK PTPNMVIREG KHVDARGRVY LPGLHNWDYP
     KSSVVGLLNE MIAKFEEDPP LSSKTAGENK DPHELLAFVS NFHISDGGIR HHDQPINKVS
     VIGGGDLGMA SVMSILSKCK VEKLVFIDVA ESSTKGGSTD LEIFSLPKVE VSRDLSASAG
     SRVVVVTANA WSSEQSYVSV VQTNVDLYRG IIPNLARLSP NAVMIIASQP VDIMSHVAWR
     QSGLPPTRVI GAGCNLDSER LSHVLDINLN THKPAWVIGE LSDNKIAVMS NTGLSSSVKP
     EIAPGSSSTK PLLDRAFDIM KNRGQRSWSV GLSIADITNS VLTDKMKPHS VSTLAQGWGG
     IGAEVFLSLP CIMGANGSTR LAGVSLAQED DAKIRESVTS LSNLMSQLKI
//