ID A0A3B4ZAA8_9TELE Unreviewed; 781 AA.
AC A0A3B4ZAA8;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Papilin, proteoglycan like sulfated glycoprotein {ECO:0000313|Ensembl:ENSSPAP00000003454.1};
GN Name=PAPLN {ECO:0000313|Ensembl:ENSSPAP00000003454.1};
OS Stegastes partitus (bicolor damselfish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Stegastes.
OX NCBI_TaxID=144197 {ECO:0000313|Ensembl:ENSSPAP00000003454.1, ECO:0000313|Proteomes:UP000261400};
RN [1] {ECO:0000313|Ensembl:ENSSPAP00000003454.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3B4ZAA8; -.
DR STRING; 144197.ENSSPAP00000003454; -.
DR Ensembl; ENSSPAT00000003521.1; ENSSPAP00000003454.1; ENSSPAG00000002606.1.
DR GeneTree; ENSGT00940000156891; -.
DR Proteomes; UP000261400; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR GO; GO:0030198; P:extracellular matrix organization; IEA:InterPro.
DR Gene3D; 2.60.120.830; -; 1.
DR Gene3D; 4.10.410.10; Pancreatic trypsin inhibitor Kunitz domain; 1.
DR Gene3D; 2.20.100.10; Thrombospondin type-1 (TSP1) repeat; 5.
DR InterPro; IPR013273; ADAMTS/ADAMTS-like.
DR InterPro; IPR045371; ADAMTS_CR_3.
DR InterPro; IPR010294; ADAMTS_spacer1.
DR InterPro; IPR002223; Kunitz_BPTI.
DR InterPro; IPR036880; Kunitz_BPTI_sf.
DR InterPro; IPR020901; Prtase_inh_Kunz-CS.
DR InterPro; IPR000884; TSP1_rpt.
DR InterPro; IPR036383; TSP1_rpt_sf.
DR PANTHER; PTHR13723; ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE; 1.
DR PANTHER; PTHR13723:SF317; PAPILIN ISOFORM X1; 1.
DR Pfam; PF19236; ADAMTS_CR_3; 1.
DR Pfam; PF05986; ADAMTS_spacer1; 1.
DR Pfam; PF00014; Kunitz_BPTI; 1.
DR Pfam; PF19030; TSP1_ADAMTS; 4.
DR Pfam; PF00090; TSP_1; 1.
DR PRINTS; PR01857; ADAMTSFAMILY.
DR PRINTS; PR00759; BASICPTASE.
DR SMART; SM00131; KU; 1.
DR SMART; SM00209; TSP1; 5.
DR SUPFAM; SSF57362; BPTI-like; 1.
DR SUPFAM; SSF82895; TSP-1 type 1 repeat; 5.
DR PROSITE; PS00280; BPTI_KUNITZ_1; 1.
DR PROSITE; PS50279; BPTI_KUNITZ_2; 1.
DR PROSITE; PS50092; TSP1; 5.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157,
KW ECO:0000256|PIRSR:PIRSR613273-3}; Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 679..729
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000259|PROSITE:PS50279"
FT REGION 527..575
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 730..781
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 527..548
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 560..575
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 737..754
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 16..51
FT /evidence="ECO:0000256|PIRSR:PIRSR613273-3"
FT DISULFID 20..56
FT /evidence="ECO:0000256|PIRSR:PIRSR613273-3"
FT DISULFID 31..41
FT /evidence="ECO:0000256|PIRSR:PIRSR613273-3"
SQ SEQUENCE 781 AA; 85816 MW; 6EE52689E0292D2A CRC64;
VPGGDYWESW GPYGDCSRSC GSGVTVRTRR CITHTDGGHN CVGPDKSYSS CNIQDCPEGS
KDFREEQCSK FDGTDFQGKR FKWLPYYGEN PCELICMPRG ENFFYRHGNA VVDGTPCHPG
RRDICVDGVC KRLGCDSILE SHQQEDPCLQ CGGNGQSCHQ VKNSFKVYNQ MFIIPVGATT
ISIRETVASR NYLIKNLRGE YYLNGHWVIE FSRATPIAGT VLFYQRGAEG DNVPETIIGR
GPTTEPLVVE LISQEPNQGV EYEYYLPNGR SRDGYYWSFG SWSACSRECG SYQSRLVFCT
IDNEAYSDYL CASLPRPQTN RTCNPHQCPQ VRMAYLYPPQ LWRSSERPRA YWKTGEWNAC
SVTCGGGSQL RSVQCISHDA SGPRVVEDAV CAAYAEAPPT LQTCNMHKCA EYQVTAWSAC
SVTCGSGEQT REVTCVGSGG MRLEETSCST LLRPAAVQPC QMVACSRQIS WHVGEWGLCS
RSCGSGSRER QVICSDQERN LYPVAQCSAQ PKPTTVERCN SQPCYSPQVP SVQDPRGHDN
SQTGFQPYVP DHATRRPETR DPAQTNTVQD PHSSAPALHC SQSYYGCCPD GRTSAGGPQG
LGCPHTPAPT PSQPSCSRTY GCCQDGVTAA QGPNMLGCAA PSLPTENAVQ CRTTTYGCCY
DRTTPAEGPN GEGCPNPPNH LPRGAGSCSG WVSRYHFDVI TSKCVHFWYG GCHGNSNNFM
TRAECQRACP GPSHQADPRR GVHRQDRPLH RGGSGRPDGR AALQSQSSAF VRRRRGVETR
R
//
