ID A0A3B4ZBY1_9TELE Unreviewed; 2063 AA.
AC A0A3B4ZBY1;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=ATP binding cassette subfamily A member 7 {ECO:0000313|Ensembl:ENSSPAP00000004019.1};
GN Name=ABCA7 {ECO:0000313|Ensembl:ENSSPAP00000004019.1};
OS Stegastes partitus (bicolor damselfish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Stegastes.
OX NCBI_TaxID=144197 {ECO:0000313|Ensembl:ENSSPAP00000004019.1, ECO:0000313|Proteomes:UP000261400};
RN [1] {ECO:0000313|Ensembl:ENSSPAP00000004019.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR Ensembl; ENSSPAT00000004102.1; ENSSPAP00000004019.1; ENSSPAG00000002631.1.
DR GeneTree; ENSGT00940000161439; -.
DR Proteomes; UP000261400; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03263; ABC_subfamily_A; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR026082; ABCA.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR19229; ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA; 1.
DR PANTHER; PTHR19229:SF49; PHOSPHOLIPID-TRANSPORTING ATPASE ABCA7; 1.
DR Pfam; PF12698; ABC2_membrane_3; 2.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 23..42
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 557..576
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 596..619
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 631..654
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 660..682
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1218..1239
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1488..1510
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1530..1555
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1567..1587
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1599..1620
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1683..1702
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 803..1034
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 1744..1975
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 2063 AA; 232388 MW; 22235121B3D16A74 CRC64;
MGIFRQLYLL LWKNITYRRR NKIQLIIELL WPLFLFVILI SVRHSHPPYK QSQCECHFPN
KALPSAGTLP WIQGIICNIN NPCFHSPTAG ETPGQAVKIC EVIVWHQICP LQPTLTGAQM
QIKDLVCNAS MLGQMLIVDG GEGAMTDLQT QLCDQPADVL QEAERLFLSQ LDLTKFATVG
TSWHGNLCFF SSLSSFAEMS AALRLLSPEN RTALPRESFR AFTRIMCGHP EIGGERIPSL
NWYEDNDIKS FLGKNGTEDL DLDRDNNTTP FCKSLIHGLE SNPLSRIVWR GIKPLFIGKL
LYTPDSPAVR QVMKEVNKTF EDLQIIQELN EAWMEVGPRI KNYMETSVEI HVMHLMPSGI
AVLVNLRLEN TPWTASRIAR FLSTPSPDTP RQPGAPPNWL DVYNDLSHTI TTLAQVTECF
SLNKLEGLET EGQLIDRALE LLEDRQYWAG VVFLLPNSSS SDLPPHVTYK IRMDIDDVTR
TNKIKDRFWD PGPAADPFSD MRYIWGGFVY IQDLVERAVS RVLTGVQQTT GIYIQQMPYP
CYVDDVFLRV LNRSLPLFMT LAWIYSVAMI IKGVVYEKEA RLKETMRIMG LGTGTLWFSW
FISSLVPFLI SAALLIALLK WGDILPYSDP AVVFFFLMAF ATATIMQCFL ISTFFSKANL
AAACGGLIYF GLYLPYVLCV AWRDRLNTTH RSFLSPVAFG FGCEYFSQYE EQGVGIQWYN
LRFSPVEGDT YSFTTSILML YVDAFIYAIA AWYIEAVFPG EYGIPRPWYF IFQINYWGGI
PLESKDCTGN RIEAEPSNLI LGVSIRNLVK IYKKGAKLAV NHLNLKFYEG QITSFLGHNG
AGKTTTISVL TGLFPPTSGT VYIKGMDIRH DMDIIRKTLG VCPQHNVLFD ILTVEEHVWF
YGRMKGLSEE QVNAELETLL DDVGLLHKRH DQTRNLSGGM QRKLSVAIAF VGGSKVVVLD
EPTAGVDPYS RRGIWDLLLK YRKDRTIILS THYMDEAELL GDRIAIISQG KLCCCGSPLF
LKSRLGSGYY LTVVKREGMD TSTPSSSSIC TSTSISTNKL ESSLSEDTGL GSEESSSCES
LLALVQHHIP GARLVEESRC EAVINLPQTA AKDSSLALFL SDLDQKLAEL GIRSYGLSDS
TLEQIFLRVA EETGVDSEPG HQTYHPVFML VAEPQETDLL SGDGRGGVPL TGWWLTWQQL
RALFVKRWLY ARRSRRGFLA QIVLPAVFVL IALLFSLIVP PFGKYPALQL QPWMYGEQYT
FFSNDAPGNP AIESLLEALL DQPGFGTKCM ENEQEENSTN PQCGSERRGP LMRPQVSFST
WQMFSKGNWS RNRPSPDCQC STENIRRMLP ECPEGAGGMP PPQIKRLTGD ILQNLTSYNI
SDYLVKTYSQ ILKKRYSTQY NTLHFYRIPF VTFVGHEDNN LHIYVWYNNK GWHAMVSFVN
VMNNGLLRAS LPPGPERRKY GITAYNHPLN LTKEQLTEMA MMTTSVDVLV SICVIFAMSF
VPASFVLFLI EERVSKAKHL QFVSGVKPIL YWLANFVWDM LNYTVPATMV VLIFISFQQQ
SYVSETNLPA LVLLLLLYGW SITPLMYPAS FVFTVPSTAY VVLTSINLFI GINGSIATFV
LELFHLNEVN RILKKVFLIF PHFCLGRGLI DMAKNQAMAD AFQRLGTKQT LDPLEWDFVG
KNLFAMAAQG VIFFIFTILL QYKFFIRFRP WWVEPEMAPL GPEDEDVAKE RERVKSGKAQ
SDILTMMDLS KVQPTYKCKT EIVCVVVHLP NCFGLLGVNG AGKTSTFRML TGDTPITHGE
AFLNHYSVLT EMERVHQLMG YCPQFDAISD LLTGREHLEL YARLRGVPEE SVTKVAQWGV
KKLGLTQYAE QEAGGYSGGN KRKLSTAISL IGAPPVIFLD EPTTGMDPKA KRFLWNCILS
VTKEGRAVVL TSHSMEECEA LCTRMAIMVN GRFQCLGSVQ HLKNRFGDGY TIILRLADTK
VDPDLCPVDA YVMKSFPSIQ LKERHQNVLQ YQLPSHTCCL ARVFDVLANN YEELGIIDFS
ISQTTLDQVR GKGDENAETS RAG
//
