ID A0A3B4ZC21_9TELE Unreviewed; 707 AA.
AC A0A3B4ZC21;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Solute carrier organic anion transporter family member {ECO:0000256|RuleBase:RU362056};
GN Name=SLCO1C1 {ECO:0000313|Ensembl:ENSSPAP00000006080.1};
OS Stegastes partitus (bicolor damselfish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Stegastes.
OX NCBI_TaxID=144197 {ECO:0000313|Ensembl:ENSSPAP00000006080.1, ECO:0000313|Proteomes:UP000261400};
RN [1] {ECO:0000313|Ensembl:ENSSPAP00000006080.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU362056};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU362056}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the organo anion transporter (TC 2.A.60) family.
CC {ECO:0000256|ARBA:ARBA00009657, ECO:0000256|RuleBase:RU362056}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU362056}.
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DR AlphaFoldDB; A0A3B4ZC21; -.
DR STRING; 144197.ENSSPAP00000006080; -.
DR Ensembl; ENSSPAT00000006202.1; ENSSPAP00000006080.1; ENSSPAG00000004670.1.
DR GeneTree; ENSGT01080000257336; -.
DR Proteomes; UP000261400; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006811; P:monoatomic ion transport; IEA:UniProtKB-KW.
DR Gene3D; 3.30.60.30; -; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR002350; Kazal_dom.
DR InterPro; IPR036058; Kazal_dom_sf.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR004156; OATP.
DR NCBIfam; TIGR00805; oat; 1.
DR PANTHER; PTHR11388; ORGANIC ANION TRANSPORTER; 1.
DR PANTHER; PTHR11388:SF99; SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 1C1; 1.
DR Pfam; PF07648; Kazal_2; 1.
DR Pfam; PF03137; OATP; 1.
DR SUPFAM; SSF100895; Kazal-type serine protease inhibitors; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS51465; KAZAL_2; 1.
DR PROSITE; PS50850; MFS; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Ion transport {ECO:0000256|RuleBase:RU362056};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362056};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362056};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362056}; Transport {ECO:0000256|RuleBase:RU362056}.
FT TRANSMEM 46..66
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 87..107
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 119..141
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 220..241
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 274..294
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 355..373
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 393..413
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 425..445
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 544..571
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 583..606
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 634..658
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT DOMAIN 53..663
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
FT DOMAIN 464..519
FT /note="Kazal-like"
FT /evidence="ECO:0000259|PROSITE:PS51465"
SQ SEQUENCE 707 AA; 77310 MW; 3963A3D9F400BA62 CRC64;
MICCVESASQ LEHSSWKEEL LFSNSLCIAG ATRCCLKFHT SSSLRLSRSC SMFLAALSFA
YFAKALSGSY MKSTITQLER RFDIPSYLIG IIDGSFEIGN LLVIAFVSYF GAKLHRPKII
AVGCILMSFG TFLIAMPHFI IGRYKIETSI RSSVNSTNNL SPCPASSPES SRAAAGCERE
SSVSMWIYVL LGNVLRGIGE TPVQPLGISY IDDYAQTENA ALYIGCVQTI SIIGPVFGYL
LGSLCAKIYV DVGYVDMETV TITPGDARWV GAWWLGYLIA GAITLMSAVP FWFLPKSLPM
PVEKHDTMCT PEQTRFIKDS PTMEHKFRPE EPPNLHLMAN EFVPTLKNLL GNPVYIIYLC
VTIIQFNSLI GMVTYKPKYI EQHYGQSASK ANLLMGMINI PAVAVGMFSG GVVMKKYKLG
IMGAAKFAFG TSLVGYLLSL LFLALGCENS KVAGITVSYT GYELSLFSDC NSGCLCSRRE
WDPVCGENGI TYVSPCLAGC TSFSGSGRNT VLDDCRCVAA ANPRPGNLTA TLGQCTHRDS
CDRIFPYFMA LSVLSSFIIS LGGTPGFMLL VRCIKPELKS LALGIHTLAT RTLAGIPAPI
YFGAIIDTTC LKWGYKTCGG RGACRIYNTS AYRIVYLGLT LGLRTVSFFL CILGFALLKR
HIKKEEKNAL TNGNAELESL RKEESSSLHC EQFILALDCN PDRETRL
//
