ID A0A3B4ZK44_9TELE Unreviewed; 556 AA.
AC A0A3B4ZK44;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=Endonuclease/exonuclease/phosphatase family domain-containing protein 1 {ECO:0000256|ARBA:ARBA00015260};
GN Name=eepd1 {ECO:0000313|RefSeq:XP_008286081.1,
GN ECO:0000313|RefSeq:XP_008286082.1};
OS Stegastes partitus (bicolor damselfish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Stegastes.
OX NCBI_TaxID=144197 {ECO:0000313|Ensembl:ENSSPAP00000008705.1, ECO:0000313|Proteomes:UP000261400};
RN [1] {ECO:0000313|Ensembl:ENSSPAP00000008705.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_008286081.1, ECO:0000313|RefSeq:XP_008286082.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_008286081.1; XM_008287859.1.
DR RefSeq; XP_008286082.1; XM_008287860.1.
DR AlphaFoldDB; A0A3B4ZK44; -.
DR STRING; 144197.ENSSPAP00000008705; -.
DR Ensembl; ENSSPAT00000008862.1; ENSSPAP00000008705.1; ENSSPAG00000006629.1.
DR GeneID; 103361705; -.
DR CTD; 80820; -.
DR GeneTree; ENSGT00390000009677; -.
DR OrthoDB; 3037349at2759; -.
DR Proteomes; UP000261400; Unplaced.
DR Proteomes; UP000694891; Unplaced.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR CDD; cd10283; MnuA_DNase1-like; 1.
DR Gene3D; 1.10.150.280; AF1531-like domain; 1.
DR Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR Gene3D; 1.10.150.320; Photosystem II 12 kDa extrinsic protein; 1.
DR InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR InterPro; IPR005135; Endo/exonuclease/phosphatase.
DR InterPro; IPR003583; Hlx-hairpin-Hlx_DNA-bd_motif.
DR InterPro; IPR010994; RuvA_2-like.
DR PANTHER; PTHR21180; ENDONUCLEASE/EXONUCLEASE/PHOSPHATASE FAMILY DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR21180:SF32; ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE FAMILY DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF03372; Exo_endo_phos; 1.
DR Pfam; PF12836; HHH_3; 2.
DR SMART; SM00278; HhH1; 3.
DR SUPFAM; SSF56219; DNase I-like; 1.
DR SUPFAM; SSF47781; RuvA domain 2-like; 2.
PE 4: Predicted;
KW Endonuclease {ECO:0000313|RefSeq:XP_008286081.1,
KW ECO:0000313|RefSeq:XP_008286082.1};
KW Hydrolase {ECO:0000313|RefSeq:XP_008286081.1,
KW ECO:0000313|RefSeq:XP_008286082.1};
KW Nuclease {ECO:0000313|RefSeq:XP_008286081.1,
KW ECO:0000313|RefSeq:XP_008286082.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000694891}.
FT DOMAIN 49..68
FT /note="Helix-hairpin-helix DNA-binding motif class 1"
FT /evidence="ECO:0000259|SMART:SM00278"
FT DOMAIN 79..98
FT /note="Helix-hairpin-helix DNA-binding motif class 1"
FT /evidence="ECO:0000259|SMART:SM00278"
FT DOMAIN 135..154
FT /note="Helix-hairpin-helix DNA-binding motif class 1"
FT /evidence="ECO:0000259|SMART:SM00278"
FT REGION 105..127
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 194..220
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 194..217
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 556 AA; 60860 MW; 23379DB05E05966F CRC64;
MGGSLGCHRS IPKDPTDFSC GKRKFSAACN FGNILVNQER LNINTATEEE LMTLPGVNRT
VAQNIVEYRD CIGGFKKVED LALVSGIGAT KLEVIKLEIC VSSRTSSSQH SPSSLRKDLE
HQSSTGMNIN TATPAQLMSI RGITEKIAKN IVAYRAEHGP FKSIEDLVRV NHINSSLLDK
IRFQVFVERS RAPSTNTNGG LTCTTKSHPS PTSFSLRSDD LDLPPGGPTQ IISVRPNVEP
PLGLRDGKPV VRVATWSLQG CSCDKANNPG VKEVVCMTLL ENDIKLLAVQ DLLDREALDK
FCVELNQGTL ASIRKWKWPR GLWKSIVSEK PTGHSGKGVS YSGYLWDSSS GIDLKDAAVL
ESPVVNGNGS HTYPRLYLAH FLIGSYELTV VNVHMQATAA PGDSSSKNQS SDEVKCQRLS
PSIQETLKAE KELVILGDFG SSPQCSELDV LRKEKLCALI PSTQFTNIST RSPQGTRCLD
NVWVSRSLKK IYSGHCMVVR EGLTNPWIPD NWSWGGVASD HCPVVAEFYV DPSSKELSRP
GMTVVDRGDI MPKHER
//
