ID A0A3B4ZKU7_9TELE Unreviewed; 846 AA.
AC A0A3B4ZKU7;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=Potassium voltage-gated channel subfamily KQT member 4-like {ECO:0000313|Ensembl:ENSSPAP00000008960.1};
GN Name=KCNQ5 {ECO:0000313|Ensembl:ENSSPAP00000008960.1};
OS Stegastes partitus (bicolor damselfish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Stegastes.
OX NCBI_TaxID=144197 {ECO:0000313|Ensembl:ENSSPAP00000008960.1, ECO:0000313|Proteomes:UP000261400};
RN [1] {ECO:0000313|Ensembl:ENSSPAP00000008960.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR AlphaFoldDB; A0A3B4ZKU7; -.
DR STRING; 144197.ENSSPAP00000008960; -.
DR Ensembl; ENSSPAT00000009122.1; ENSSPAP00000008960.1; ENSSPAG00000006804.1.
DR GeneTree; ENSGT00940000155933; -.
DR Proteomes; UP000261400; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 6.10.140.1910; -; 2.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 1.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR003937; K_chnl_volt-dep_KCNQ.
DR InterPro; IPR013821; K_chnl_volt-dep_KCNQ_C.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR47735; POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 4; 1.
DR PANTHER; PTHR47735:SF8; POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 5; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR Pfam; PF03520; KCNQ_channel; 1.
DR PRINTS; PR00169; KCHANNEL.
DR PRINTS; PR01459; KCNQCHANNEL.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Calmodulin-binding {ECO:0000256|ARBA:ARBA00022860};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 52..71
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 119..138
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 176..202
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 8..206
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT DOMAIN 333..513
FT /note="Potassium channel voltage dependent KCNQ C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03520"
FT REGION 298..371
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 536..635
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 754..786
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 304..322
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 554..569
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 587..617
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 846 AA; 93005 MW; B06AFF3D933B4F0E CRC64;
AHQEFSSHCL LILEFVMIVV FGLEYIIRIW SAGCCCRYRG WQGRLRFARK PFCVIDIIVL
IASVAVVSAG SQGNIFATSA LRSLRFLQIL RMVRMDRRGG TWKLLGSVVY AHSKELVTAW
YIGFLVLIFS SFLVYLVEKE FNKDFATYAD ALWWGTITLT TIGYGDKTPQ TWTGRLLSAG
FALLGISFFA LPAGILGSGF ALKVQEQHRQ KHFEKRRNPA ASLIQCVWRS YAADENSVSI
ATWKPHLKAL HTCSPLKKKK ERGEAREARR GEIGAFREGG RRQREICDQK LSFKERVRMA
SPRGQSMKSR QTSINDRQRC SPGNEVVGSG ELMGGSPAKV QKSWSFNDRT RFRPSLRLKS
QPRTPVPDVD AGMATEDSFD ERGCHCDVTV EDLSAALKAV IRAVRIMKFH VAKKKFKETL
RPYDVKDVIE QYSAGHLDML CRIKSLQTRV DQILGKGQIP VDKKMRDKLH PDGDSLEGMS
MLGRVCKVER QVTSIESKLD SLLDVYRQVL QKGSSALTLS SLPLFELDNH QHHNSSYPTS
IIGRDLPSPQ GGNSVGGGGD NNTGMHRSLS ANPRGLRLIL APADDDGPPD SAPPSYPPST
ASLSPSPLLP PDSPYPTLVT PNSKKAHFPD LPPPPPSAGS FTLQLPPMVH PSHLRCPPEP
VPDDDLTGEV VAGEGSLGPA VVVGCSVDQK EDSEAGSVQG RVQLREKPGL KPEGVWRRHM
SLEVNPLLLL SSSPEGRPSD WEGSLGKSLS AHNLSQPLTN RAPGLSSALN NSSSSNSSER
GNAHSHLSNW DGTELFIREP TAEHFNFLSQ GPSSSPSDLL QTVEEAVLHP KGNSEFLSQS
SHIQLA
//
