ID A0A3B4ZUN2_9TELE Unreviewed; 3906 AA.
AC A0A3B4ZUN2;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=PKHD1 like 1 {ECO:0000313|Ensembl:ENSSPAP00000011506.1};
OS Stegastes partitus (bicolor damselfish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Stegastes.
OX NCBI_TaxID=144197 {ECO:0000313|Ensembl:ENSSPAP00000011506.1, ECO:0000313|Proteomes:UP000261400};
RN [1] {ECO:0000313|Ensembl:ENSSPAP00000011506.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR Ensembl; ENSSPAT00000011710.1; ENSSPAP00000011506.1; ENSSPAG00000007780.1.
DR GeneTree; ENSGT00940000157594; -.
DR Proteomes; UP000261400; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00102; IPT; 1.
DR CDD; cd00603; IPT_PCSR; 11.
DR Gene3D; 2.60.120.1560; -; 1.
DR Gene3D; 2.60.40.420; Cupredoxins - blue copper proteins; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 13.
DR Gene3D; 2.160.20.10; Single-stranded right-handed beta-helix, Pectin lyase-like; 1.
DR InterPro; IPR008972; Cupredoxin.
DR InterPro; IPR019316; G8_domain.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR002909; IPT_dom.
DR InterPro; IPR037524; PA14/GLEYA.
DR InterPro; IPR011658; PA14_dom.
DR InterPro; IPR006626; PbH1.
DR InterPro; IPR012334; Pectin_lyas_fold.
DR InterPro; IPR011050; Pectin_lyase_fold/virulence.
DR PANTHER; PTHR46769:SF2; FIBROCYSTIN-L; 1.
DR PANTHER; PTHR46769; POLYCYSTIC KIDNEY AND HEPATIC DISEASE 1 (AUTOSOMAL RECESSIVE)-LIKE 1; 1.
DR Pfam; PF10162; G8; 2.
DR Pfam; PF07691; PA14; 1.
DR Pfam; PF01833; TIG; 13.
DR SMART; SM01225; G8; 2.
DR SMART; SM00429; IPT; 11.
DR SMART; SM00758; PA14; 1.
DR SMART; SM00710; PbH1; 8.
DR SUPFAM; SSF56988; Anthrax protective antigen; 1.
DR SUPFAM; SSF81296; E set domains; 13.
DR SUPFAM; SSF51126; Pectin lyase-like; 2.
DR PROSITE; PS51484; G8; 2.
DR PROSITE; PS51820; PA14; 1.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00022989};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 294..443
FT /note="PA14"
FT /evidence="ECO:0000259|PROSITE:PS51820"
FT DOMAIN 1939..2059
FT /note="G8"
FT /evidence="ECO:0000259|PROSITE:PS51484"
FT DOMAIN 2721..2867
FT /note="G8"
FT /evidence="ECO:0000259|PROSITE:PS51484"
FT REGION 3847..3868
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3906 AA; 424131 MW; FF4F06CBEED103CE CRC64;
MSSICFVLAA QRIDYVSPRR GSQSGATRLT ISGAGFSKTE FKLKPEDAHL GNLVTLVSST
KSFPCDVERD STHENQIMCY TRAMPASHYM VHVTVDGVPI PESSRCRGSH AWYHCSFYPV
WYRTPTIESV SPVSGPPGTL VTMRGRIYTN VYGSNTDRSS NGLNVRFLRY NLRLDSESSH
WGYMSCKMTG TYVGEPLSST VKLSYPAKKL LSVSAADKLS MFQTFAEVTG VSPSAGGVLG
GTLITVHGRF FDETDRPARV LVGGRPCEIQ SVADDRITCR TPEQPKNMNM SVYPGGRGLK
MEVWNQTRPR YLSDIWSYNE STPGYWQQPV DSLPQVFSLE LDYFTTRSRG FLVPPTSGNY
TIYLGCDDRC DLYLSNSSRP EDKVRRNNFK TMKSQKSDVM ALEEGKFYYI EVLQQDYGGK
ARVNIALYRE ESSFTEEQTD DAVNEVQQIV ADYDVFDEEQ VVSFDSWPSR TAAVQEVQKL
SVSSSCQSHL CGNTFFRLSY GDAKTAPIPV GASAGVMEAA LNSLWSIRPD SVRVAKQDDG
QGSHYTVTFN SDRGDFDLLH SEVFTNDTNI IVAEETKGQS NMETFTLLWA GIPTKPIAVN
ATESEVCDAQ NPITYLLERH PVSGLYSTLT ARVKSSLVSV MVNTPECRRS LTQMIFLMLK
SNYSPCSTKA QSQYRPQTDV WSYKCLDLQS SLQTEFFGSS YSLLSLHLHK DESRADFYVD
AVYIGKTPTT RDVNGTEQHL RPALSSGRHE EVTRCLSSGL SMDIGEDELK YALEGIEGIG
QVSVTDKGTC RQPKWRIKWL TKGGAQPLMK VDSSSVVGEN VVISVKEVEK GGLLIRGLSG
DFFRSWETKP QVQVLINGIP SKCSGNCSFE WRDERTPVLT GISPTQGSDG LGTLLTITGT
GFSSENASIT VGKAKCRVEQ VCRLSSSSAG SYPVWVNFPS LGDARHPGGD VLRFTYQLIV
SSFSPTSGSL AGGTLLTVSG FGFGQNSSVS VGGGECSLVH VTDTELKCRT PAVMSVGNAS
QSAGGSFTFD GNATPQISGL SPQRSTVTGR VLTIQGSNLG GRDNSSVVLV GGEECVTVQW
TETSITCLLP VLPPGLHKVD VQVGNNGYPQ TSNGVNATIE YILEVHSISP SSGSLMGGTM
LTVSGAGFSN NTADNKVSID ARCEVTVASE NELRCVVQSE QKIHNVTNQG SHHTYGQGYA
WSPSSLTVFV GDTVMWRWEA PLFQKVGYRV FSVSNASSAT PGRGPLNSGE MKTAKGFHSY
QFTAPGVFLY SSGYIDNKKA IMLQGVVKVR SRVEKTSSRR VSRAAPQCVA SPQCQQTNET
SGGFSYSTSA CSTPTVHSIS PNQGSYHQVI RIQGTGFSNI TCANEVMVGD QPCQVINSSQ
SEITCQLGPN SELPTGVALA VSVRVNNLGD AIIAVQDELK RRFVVLPVVD SVSPPIGSTT
GYTRLLVRGS GFSSGRVTVA GEPCSVLTLN YTHIVCDTAP SQPHTGDVVF HKGRIQSSCS
SSCSFVYSSA VTPTVTGISP DTIDTAINVT ISGSGFGSRV DDLSVFANTT ELEVTAVTDG
NITATVTALP AGIHLLRVTV RSKGLASGSV TLNSRAKAIL SPTAGSLAGG TPLVFTGNGF
APGNTSVTVG GKPCEIQTVT PARLRCLTPP HAEGLVTANI RVLSVDYPPL NFTYSAAHTP
VISSVRPSGS VVTLTGSGFG NDSQLVSVTI NGVACNVSMV SDTQVQFTAA NNPGGAYKVM
LLHQDKGYAQ SDAMFTYELR LDTVTPNESG FGGGRLLSLL GSGFSETSVV KICEQECVVS
RETSTSTRLY CEAPPNNGTQ SELDCDISVI NPLSSVNKSS AFTYRSRLTP VITEVSPRRG
GTAGGTRLTI SGSGFSKVNV TIAGSVCDVQ SANDTHIVCV TNSQKQSQET KVRVNVADRG
LAKMDNADFF YVDVWSSRFT WGGLSPPEKG SFAVITKNQT ILLDTSTPVL KMLLIQGGTL
VFDEADIELQ AENILITDGG RLQIGQEGAP FQHKAIITLH GHLRSQEIPV YGTKTLAVRE
GILDLHGIPV PVPWTHLAQT AASGSATLTL MKAVTWKVGD EIVIASTGHR HSQKENEVRK
IAAVSADGRT LTLDKPLNYT HVGVSVTLPD GTVFEGRAEV GLLTRNIVIR GSRHQEWTDE
IKACPDGFNT GEFATQTCFQ GRFGEEIGSD EFGACIMFHA PRPNENLAIG RLEYVEITHA
GQAYRLGRYP IHWHLMGNIS YASYVRGCAI HETFNRAVTI HNTHRLLVEH NVIYNIMGGA
FFIEDGIETE NILQYNLAVF VKQSTSLLND DVTPAAYWVT NPNNIIRHNA AAGGTHFGFW
YRMHEHPDGP SFDSNICQKK VPLGEFTNNT VHSQGWFGLW IFQDFFPMKK GSCRSKTPEP
AIFHSLTTWN CEKGAEWVNV GAVQFSNFVM VNNEKAGIEG KRIMQWAVSG FGEDGGATMS
NSTIVGHVDE LGRLKNNCTH RGIITPFDDG LSVLNTKFIN FNRDSCTAIG VTSIDGTCVD
RCGGWAVRFS GVQYFNSPNK AGFRWEHEVQ LLDTDGSLTG TKSLRVVPMS SLLDPAHCSQ
SAEWSVGFPG AVCDHTVDFH RLALNNPSPS SLKAKDIVLT NSHGTSVIPF LKKRMTHKFG
WMGLLPSGQT YNWYFDNVDQ VTNITYKAKF YGFKPDQFVI INHNFTQSPD SFRIIDKRNG
SSAPLSFGNN SNGDCLWSNA SFWSNSAENN NSVPAEGADV VVPSGMWLVL DVDPPRLNKL
TVVGVLEIPD TLNSSSSRSA RSAPEFRTVV VDAVYISIQG GRLIAGWDGE PFRGELHIKL
RGNHKTPDWP LPNGPNQGSK VLGEKTALHL SHMTDDTSAP VIGFVIACLH AAPVCCLQVG
DEVVVSTTSY DINETEKCQI AAVSADGRTL TLSQSLAHTH IGETHSVSGS SRSYTLAADV
GLVTRNIKIV GQDYPQMTEE SFGARLLVGS YSWKGIDYKG KAQIRNVEFY RSGQEGWTDY
SDPRYSVAFV NLGESYIQGC AFHDGFSPAI GVFGTEGLSV DDNVVHHTVG EGLRIWGNNI
TVRRNLVMMS LWPGSYQDRE EPFNFDWNAA IEVNEGTNVV LQNNIVAGYE RVAYRIDGEP
SFATNEKWMD NEAHGGLYGV YLNKDGLPGC SLVQGFFIWR SFDYGIYFQN TINMVISNVT
LVDNGMGVMP LTYAPPSLSH AFADKTVKSS LIVGSSPNFD CSLGLDSSDF NIATSASHRA
PRPRQGGRSG VCWPNFASGH NTAPGKPHHL NMNYNAIKGL MTVTGTTFVN FRNVCSGEAN
FMFMTNPLNE DLQHPVQVSD LKLVDSTDEA KIFVHRADVG KVNPADCVDM ECDAKKKTML
KDLDGSLLGA VGAVVPQSEF EWNGDPRRGL GDYRIPKVML TYPNGSRIPV DQIAPNKGVI
RKNCTYMTSW QSYKCFDLNY RMLVIESLDS DTETRRLSPV AVLGDGFVDL INGPQDHGWC
SGYTCQKRVS LFHSIVATNR YFDVFFTSVS PQKLRLMMLN ADPSESIVVS VFYSKPQRLD
VYVDNTLVVP TNAEWNADRS DYTLKKPISY VPQLNATLGT NYFDQDNKML KVVVRGSKPV
EIRTAPVLVI AFDLPALTED EFFGDNLVRN LATFLQVPAN MIRITNIIRG DGRRRKRSTG
LKVEVEIKKP PVQQATNTTD AQMKLTPLCY NLVQAAVSGN ISQSIGFNVS SMGVVPPPPP
SSDPSWKEVK EPEKSYVATV ADLLLVEEPV VGEFIGPLNQ QPRLMAVDEK GNCVSVGVTT
LTVTASLKSS SGDGVDGLEG NATILFSSCW ANFTDLTSVI ARLLPAGENL TMVFTLKEWS
AQSRAFSVQE KNTTTETPTT VTSTTDGPTT TDGSVFGSST VVSAGSLCLV SVIYSVACCS
DAIPIC
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