ID A0A3B4ZXC0_9TELE Unreviewed; 600 AA.
AC A0A3B4ZXC0;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Potassium voltage-gated channel subfamily C member 4 {ECO:0000313|Ensembl:ENSSPAP00000006357.1, ECO:0000313|RefSeq:XP_008294488.1};
GN Name=KCNC4 {ECO:0000313|Ensembl:ENSSPAP00000006357.1};
GN Synonyms=kcnc4 {ECO:0000313|RefSeq:XP_008294488.1};
OS Stegastes partitus (bicolor damselfish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Stegastes.
OX NCBI_TaxID=144197 {ECO:0000313|Ensembl:ENSSPAP00000006357.1, ECO:0000313|Proteomes:UP000261400};
RN [1] {ECO:0000313|Ensembl:ENSSPAP00000006357.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_008294488.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR RefSeq; XP_008294488.1; XM_008296266.1.
DR AlphaFoldDB; A0A3B4ZXC0; -.
DR STRING; 144197.ENSSPAP00000006357; -.
DR Ensembl; ENSSPAT00000006487.1; ENSSPAP00000006357.1; ENSSPAG00000004901.1.
DR GeneID; 103368029; -.
DR CTD; 3749; -.
DR GeneTree; ENSGT00940000158860; -.
DR OrthoDB; 1478695at2759; -.
DR Proteomes; UP000261400; Unplaced.
DR Proteomes; UP000694891; Unplaced.
DR GO; GO:0008076; C:voltage-gated potassium channel complex; IEA:InterPro.
DR GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 1.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR003968; K_chnl_volt-dep_Kv.
DR InterPro; IPR003974; K_chnl_volt-dep_Kv3.
DR InterPro; IPR005405; K_chnl_volt-dep_Kv3.4.
DR InterPro; IPR021105; K_chnl_volt-dep_Kv3_ID.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR003131; T1-type_BTB.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR11537:SF126; POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY C MEMBER 4; 1.
DR PANTHER; PTHR11537; VOLTAGE-GATED POTASSIUM CHANNEL; 1.
DR Pfam; PF02214; BTB_2; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR Pfam; PF11404; Potassium_chann; 1.
DR PRINTS; PR00169; KCHANNEL.
DR PRINTS; PR01583; KV34CHANNEL.
DR PRINTS; PR01491; KVCHANNEL.
DR PRINTS; PR01498; SHAWCHANNEL.
DR SMART; SM00225; BTB; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Potassium {ECO:0000256|ARBA:ARBA00022958};
KW Potassium channel {ECO:0000256|ARBA:ARBA00022826};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538};
KW Reference proteome {ECO:0000313|Proteomes:UP000694891};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448};
KW Voltage-gated channel {ECO:0000256|ARBA:ARBA00022882}.
FT TRANSMEM 259..280
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 287..306
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 360..381
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 402..419
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 431..460
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 36..143
FT /note="BTB"
FT /evidence="ECO:0000259|SMART:SM00225"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 468..548
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..16
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 479..506
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 518..546
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 600 AA; 67249 MW; 86E7A4E9D0F92B9E CRC64;
MISSVCVSSY RGRKSGNKPP SKSCLKEEMS RGEESDKIII NVGGTRHETY KSTLRTLPGT
RLAWLADPDP QVSSDSDAAP PSATEFFFDR HPGIFAYVLN YYRTGKLHCP ADVCGPLFEE
ELAFWGIDET DVEPCCWMTY RQHRDAEEAL EIFEPPEPED TDDDREMPRR FGIEDCPDRS
RGCCEVWQPK VWALFDDPYS SKAARGVALA SLFFILVSIT TFCLETHEAF NELQSWTELV
VTDNVTREVE RTEMVTKPIL TLVEGICVVW FTFEFLVRII CCADKIVFIK NTLNIIDFVA
ILPFYLEMGL KGLSSKAASD VLGFLRVVRF VRILRIFKLT RHFVGLRVLG HTLRASVNEF
LLLIIFLALG VLIFATMIYY AERIGAKPDD PTGSNHTHFK NIPISFWWAV VTMTTLGYGD
MYPQTWLGMM VGALCALAGV LTIAMPVPVI VNNFGMYYSL AMAKQKLPKK KKKHNPNPDV
PTDSISFGKS ETNSHRDSTQ SDTFPLAAEE SIGRNRSDSK QNGDANVALS EEEGCSLTQP
LSPSEKWSLR CSRGRDKNKK EGTCFLLTSG DPNVHTESCK DILAATGSYA QPEVTTLTRC
//
