ID A0A3B5A2A6_9TELE Unreviewed; 912 AA.
AC A0A3B5A2A6;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Seizure related 6 homolog {ECO:0000313|Ensembl:ENSSPAP00000015353.1};
GN Name=SEZ6 {ECO:0000313|Ensembl:ENSSPAP00000015353.1};
OS Stegastes partitus (bicolor damselfish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Stegastes.
OX NCBI_TaxID=144197 {ECO:0000313|Ensembl:ENSSPAP00000015353.1, ECO:0000313|Proteomes:UP000261400};
RN [1] {ECO:0000313|Ensembl:ENSSPAP00000015353.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00302}.
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DR AlphaFoldDB; A0A3B5A2A6; -.
DR STRING; 144197.ENSSPAP00000015353; -.
DR Ensembl; ENSSPAT00000015602.1; ENSSPAP00000015353.1; ENSSPAG00000011327.1.
DR GeneTree; ENSGT00940000156995; -.
DR Proteomes; UP000261400; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00033; CCP; 5.
DR CDD; cd00041; CUB; 2.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 5.
DR Gene3D; 2.60.120.290; Spermadhesin, CUB domain; 3.
DR InterPro; IPR000859; CUB_dom.
DR InterPro; IPR035914; Sperma_CUB_dom_sf.
DR InterPro; IPR035976; Sushi/SCR/CCP_sf.
DR InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR PANTHER; PTHR45656; PROTEIN CBR-CLEC-78; 1.
DR PANTHER; PTHR45656:SF1; SEIZURE PROTEIN 6 HOMOLOG; 1.
DR Pfam; PF00431; CUB; 3.
DR Pfam; PF00084; Sushi; 5.
DR SMART; SM00032; CCP; 5.
DR SMART; SM00042; CUB; 3.
DR SUPFAM; SSF57535; Complement control module/SCR domain; 5.
DR SUPFAM; SSF49854; Spermadhesin, CUB domain; 3.
DR PROSITE; PS01180; CUB; 2.
DR PROSITE; PS50923; SUSHI; 5.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00302}; Membrane {ECO:0000256|SAM:Phobius};
KW Sushi {ECO:0000256|PROSITE-ProRule:PRU00302};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 869..891
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 310..369
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 371..482
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 485..546
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 548..659
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 663..722
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 724..787
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 791..852
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT REGION 22..125
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 22..50
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 88..125
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 371..398
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00059"
FT DISULFID 693..720
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
SQ SEQUENCE 912 AA; 99431 MW; 0FF2FDFE356F365C CRC64;
MNQHPSNHIY NSLLFCAASA SEDSPSITPR GTPESGANLY PTTQDTGRRL PMITTAPPIN
VPNHHPLYRN PPQHQAPLGP HGQSHYFEDS GGPNSQSTFS KMPSGTPLDN SNKGASDQSA
ESSNMQATLT MHALAAAFHS NTHVPVSSTV LKDPEHSTVI PSAATAARAK DVRPGSDEEE
TTTTTITTTT IITTMQSPVP CQLNLTRPEG YIEAPPQSSS AFHSTMDCSY IITVYMGYGV
EVQVMNVNLS EGDKVAFEDV GHRENTMLAN ESILMRGLVV RSHSNQISIR FHSPRSQAGS
VLLRYQAFVL SCVFPQRPLY GDVSVSSLHS GGEAFFSCLT GYQLQGPSVL TCRNASTPYW
SGKEPHCLAA CGGIIRNVTV GRIVSPGFPS NYSNNLTCHW VLEAPEGQKL HIHFEKVALA
EDDDRLLIKN GNSIDAAVLY DSYEVEYLPN EGLLSTSRHL FIELTTDATG TSTGIAIRYQ
AFAAGHCYEP FVKYGNLTSS DNTWAVGAVV EFACDPGYTL EQGSVTIECM DPNNPQWNET
EPACRAVCSG EITDSAGVVL SPNWPEAYDK GQDCIWGIHV EEDKRIMLDI QVLNVGKNDL
LTFYDGDDLT AKVLGQYGGS KSRFKLYTST ADITIQFQSD PATNVYGYGN GFVVHFFEVA
RNDTCPELPE ISNGWKSTSH PELVQGTVVT YQCYPGYQVV GAELLMCQWD LTWSGDLPSC
ERVVSCADPG KVEHSRRVLS GPHFIVGSSI QYICDKGFTL SGNSLLTCFN RGSSGPMWNQ
KLPRCLPETF EPCSHPGTPN YGIPSSNKLH FQAGETLHYS CLTGHQLLGD PVLHCVPGHP
SQWSGLPPVC KGGELQLHVL STLSSQLRLY IAFATFIPVT LLLIIIIGIY LHFSKYVQIT
SDLTGKYLDI LI
//
