ID   A0A3B5A3I5_9TELE        Unreviewed;       170 AA.
AC   A0A3B5A3I5;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=Interleukin family protein {ECO:0000256|RuleBase:RU368043};
OS   Stegastes partitus (bicolor damselfish).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Stegastes.
OX   NCBI_TaxID=144197 {ECO:0000313|Ensembl:ENSSPAP00000014756.1, ECO:0000313|Proteomes:UP000261400};
RN   [1] {ECO:0000313|Ensembl:ENSSPAP00000014756.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- FUNCTION: Immune regulatory cytokine. {ECO:0000256|RuleBase:RU368043}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613,
CC       ECO:0000256|RuleBase:RU368043}.
CC   -!- SIMILARITY: Belongs to the IL-10 family.
CC       {ECO:0000256|ARBA:ARBA00008813, ECO:0000256|RuleBase:RU368043}.
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DR   AlphaFoldDB; A0A3B5A3I5; -.
DR   STRING; 144197.ENSSPAP00000014756; -.
DR   Ensembl; ENSSPAT00000014998.1; ENSSPAP00000014756.1; ENSSPAG00000011103.1.
DR   GeneTree; ENSGT00950000183124; -.
DR   Proteomes; UP000261400; Unplaced.
DR   GO; GO:0005615; C:extracellular space; IEA:UniProtKB-UniRule.
DR   GO; GO:0005125; F:cytokine activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.20.1250.10; -; 1.
DR   InterPro; IPR009079; 4_helix_cytokine-like_core.
DR   InterPro; IPR020443; IL-10/19/20/22/24/26_fam.
DR   InterPro; IPR020423; IL-10_CS.
DR   PANTHER; PTHR48394:SF5; INTERLEUKIN-19; 1.
DR   PANTHER; PTHR48394; INTERLEUKIN-19-RELATED; 1.
DR   Pfam; PF00726; IL10; 1.
DR   SUPFAM; SSF47266; 4-helical cytokines; 1.
DR   PROSITE; PS00520; INTERLEUKIN_10; 1.
PE   3: Inferred from homology;
KW   Cytokine {ECO:0000256|ARBA:ARBA00022514, ECO:0000256|RuleBase:RU368043};
KW   Disulfide bond {ECO:0000256|PIRSR:PIRSR620443-51};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525, ECO:0000256|RuleBase:RU368043};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|RuleBase:RU368043}.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000256|RuleBase:RU368043"
FT   CHAIN           27..170
FT                   /note="Interleukin family protein"
FT                   /evidence="ECO:0000256|RuleBase:RU368043"
FT                   /id="PRO_5031609525"
FT   DISULFID        34..121
FT                   /evidence="ECO:0000256|PIRSR:PIRSR620443-51"
FT   DISULFID        75..123
FT                   /evidence="ECO:0000256|PIRSR:PIRSR620443-51"
FT   DISULFID        76..125
FT                   /evidence="ECO:0000256|PIRSR:PIRSR620443-51"
SQ   SEQUENCE   170 AA;  19589 MW;  7E8079C75DEE7FF6 CRC64;
     MVMKMLLGCS VSLLLLLVCL TEPVESRTLH LDSCSVNVHM HELRKYYSDI RSNAVMFGRC
     CILTFVYLFQ EGQRCCFLRL LLRFYVERVF SNYASSQPQQ QRCSSALANA FVSIRRDIHK
     CHCLCEEDTQ RKIDSVHAEF DKLQVGQAAQ KAVGELDTVL EWLEGQRTQT
//