ID A0A3B5A655_9TELE Unreviewed; 1127 AA.
AC A0A3B5A655;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Elongation factor Tu GTP-binding domain-containing protein 1 {ECO:0000313|RefSeq:XP_008288511.1};
DE SubName: Full=Elongation factor like GTPase 1 {ECO:0000313|Ensembl:ENSSPAP00000015796.1};
GN Name=EFL1 {ECO:0000313|Ensembl:ENSSPAP00000015796.1};
GN Synonyms=eftud1 {ECO:0000313|RefSeq:XP_008288511.1};
OS Stegastes partitus (bicolor damselfish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Stegastes.
OX NCBI_TaxID=144197 {ECO:0000313|Ensembl:ENSSPAP00000015796.1, ECO:0000313|Proteomes:UP000261400};
RN [1] {ECO:0000313|Ensembl:ENSSPAP00000015796.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_008288511.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_008288511.1; XM_008290289.1.
DR AlphaFoldDB; A0A3B5A655; -.
DR STRING; 144197.ENSSPAP00000015796; -.
DR Ensembl; ENSSPAT00000016050.1; ENSSPAP00000015796.1; ENSSPAG00000011885.1.
DR GeneID; 103363503; -.
DR CTD; 79631; -.
DR GeneTree; ENSGT00550000074806; -.
DR OrthoDB; 166721at2759; -.
DR Proteomes; UP000261400; Unplaced.
DR Proteomes; UP000694891; Unplaced.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR CDD; cd01681; aeEF2_snRNP_like_IV; 1.
DR CDD; cd04096; eEF2_snRNP_like_C; 1.
DR CDD; cd01885; EF2; 1.
DR CDD; cd16268; EF2_II; 1.
DR CDD; cd16261; EF2_snRNP_III; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.70.240; -; 1.
DR Gene3D; 3.30.70.870; Elongation Factor G (Translational Gtpase), domain 3; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 3.90.1430.10; Yeast translation eEF2 (G' domain); 1.
DR InterPro; IPR041095; EFG_II.
DR InterPro; IPR035647; EFG_III/V.
DR InterPro; IPR000640; EFG_V-like.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR42908:SF3; ELONGATION FACTOR-LIKE GTPASE 1; 1.
DR PANTHER; PTHR42908; TRANSLATION ELONGATION FACTOR-RELATED; 1.
DR Pfam; PF00679; EFG_C; 1.
DR Pfam; PF14492; EFG_III; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SMART; SM00838; EFG_C; 1.
DR SUPFAM; SSF54980; EF-G C-terminal domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Elongation factor {ECO:0000313|RefSeq:XP_008288511.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000313|RefSeq:XP_008288511.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000694891}.
FT DOMAIN 17..368
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT REGION 445..483
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 930..959
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 445..464
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 465..483
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1127 AA; 125023 MW; 490208437797686A CRC64;
MGHTSLEKII ALQRNPANIR NLCILAHVDH GKTTLADCLV ASNGIISSRL AGKLRYLDSR
EDEQIRGITM KSSAISLHYK HGDQEYLLNL IDSPGHVDFS SEVSTAVRLC DGAIVVVDAV
EGVCPQTQVV LRQAWLENIR PVLVINKIDR LIMELKFTPQ EAYTHLQKIL EQVNAVTGTL
FTSKVLEERA EKEKEEEKAS ETLSGDQVYD WSAGLEEVDD SHLYFSPDQG NVVFASAIDG
WGFSIQQFAH IYSQRMGIKA SVLLKTLWGD FYLNAKAKKI MKGAQAKGKK PLFVQFVLDN
IWSLYNAVVT SRDKEKVEKV VASLGVKVMA RDLRHSDPKV LLSAICSQWL PVSQAVLSMV
CEKLPSPLDM ASERVEKLMS VGARRFDSLP EQTQKLKTAF LQCSSDENAP VIVFVSKMFA
VDTKALPQYK QRPLTQEEIA QRRELARQRH ADRMAADQTA AESHKELSHS GNTSQESQSA
GLNTAKMESL TLKDSKPEEE AELKETFIAF ARIYSGVVKK GQRVFVLGPK YDPAQGLSMI
PEGCSASDCV SDVPHLSCCS MESLYLLMGR ELEELEEVPA GNVLGIRGLE ECVLKSATLS
TAPACPPFTP LNFEATPIVR VAIEPKHPSE MPKLVRGMRL LNQADPCAEV LIQETGEHVL
VTAGEVHLQR CLDDLRDRFA KIEISASKPI IPFRETVVRP PKVDMVNEDL GKQQKVAIIH
QVKEESSQGR SSDTLHVDPS GLVTLTTPNR LATVCVRAIP LPQEVTRLLE SNSEVIRTLE
QINMSLREGK SLDISPRTLE AIAGLKDQLD NLLQGRKWRN AVEHIWAFGP RRCGPNILLN
SVESYQRLSV WQCLGRGDKT GETGAQAAVL RDFDNSIISG FQLATLSGPM CEEPLMGVCF
CVERWDIQSS APAQHQDSFE EDSISHKAFA DSKVEGSSET SAQVEGMAAG RRPEPASSDC
YGPVSGQLIA AMKEACRHAF QAQPQRLMAA MYTCEIMATA EVLGRVYGVL GKREGRVLHE
EMKEGTDMFI IKAILPVAES FGFADEIRKR TSGLASPQLV FSHWEVISSD PYWVPTTEEE
YLHFGEKADS ANQALKYMNA VRRRKGLYVE EKIVEHAEKQ RTLSKNK
//
